1-(METHYLAMINO)ADAMANTANE

Product Name: 1-(METHYLAMINO)ADAMANTANE
CAS No.: 3717-38-2
Chemical Name: 1-(METHYLAMINO)ADAMANTANE
Synonyms: Mrz-2/188;N-Methyladamantine;N-Methyladamantanamine;N-Methyl AdaMantylaMine;N-Methyl-1-adamantyamine;N-Methyl-1-adamantanamine;N-METHYL-1-ADAMANTYLAMINE;N-Methyl-adamantane-1-amine;N-Methyl-1-adamantylamine;1-(adaMantan-1-yl)-N-MethylMethanaMine
CBNumber: CB61011966
Molecular Formula: C11H19N
Formula Weight: 165.28
MOL File: 3717-38-2.mol

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1-(METHYLAMINO)ADAMANTANE Property

Boiling point:: 226.8±8.0℃ (760 Torr)
Density: 1.00±0.1 g/cm3 (20 ºC 760 Torr)
Flash point:: 84.0±15.8℃
pka: 11.32±0.20(Predicted)
form: lumps
BRN: 2348926

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26
WGK Germany: 3
RTECS: AU4375400
Toxicity: mouse,LD50,intraperitoneal,175mg/kg (175mg/kg),Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. Vol. 14(3), Pg. 59, 1980.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 727547
Product name: N-Methyl-1-adamantylamine
Purity: ≥97.0%
Packaging: 1g
Price: $191
Updated: 2025/07/31

TRC

Product number: M103660
Product name: N-methyladamantan-1-amine
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 027476
Product name: N-1-Adamantyl-N-methylamine
Packaging: 500mg
Price: $129
Updated: 2021/12/16

AK Scientific

Product number: E868
Product name: 1-(Methylamino)adamantane
Packaging: 1g
Price: $405
Updated: 2021/12/16

Matrix Scientific

Product number: 027476
Product name: N-1-Adamantyl-N-methylamine
Packaging: 1g
Price: $198
Updated: 2021/12/16

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1-(METHYLAMINO)ADAMANTANE Chemical Properties,Usage,Production

Synthesis

124-38-9

768-94-5

3717-38-2

1) In a glove box, 0.25 mmol of amantadine, 6 equivalents (1.5 mmol) of diphenylsilane, 10 mol% (based on amantadine) of cesium carbonate, and 1.6 mL of acetonitrile solvent were added to 50 mL of N2-protected Schlenk tubes.2) The N2 in the Schlenk tubes was replaced by CO2 in the double-rowed tubes by a refrigeration vacuum operation to regulate the CO2 pressure to 1 bar.3) The reaction was carried out in acetonitrile solvent at 80 °C for 72 h using cesium carbonate as catalyst, CO2 as C1 source, and diphenylsilane as reductant.4) At the end of the reaction, 0.2 mmol of ferrocene was added to the Schlenk tubes as an internal standard.5) The NMR spectra of the resulting products were analyzed by Bruker NMR analysis, which showed a similarity to the NMR spectra of the products reported in the literature (P. Besenius, P. A. G. Cormack, R. F. Ludlow, S. Otto, D. C. Sherrington, Chem. Commun. 2008) for pure N-methyl-1-adamantanamine, and the product yield was >95% under the conditions of this experiment.

References

[1] Patent: CN105753715, 2016, A. Location in patent: Paragraph 0029; 0030; 0031; 0032; 0033; 0034; 0035
[2] ACS Catalysis, 2016, vol. 6, # 11, p. 7876 - 7881

1-(METHYLAMINO)ADAMANTANE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(METHYLAMINO)ADAMANTANE Suppliers

China 51 United Kingdom 1 United States 7 Global 59

Alchem Pharmtech,Inc.

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Matrix Scientific

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3B Scientific Corporation

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AK Scientific, Inc.

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View Lastest Price from 1-(METHYLAMINO)ADAMANTANE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 1-(METHYLAMINO)ADAMANTANE 3717-38-2
Price: US $1.00/Kg
Min. Order: 1Kg
Purity: 98%
Supply Ability: 20T
Release date: 2024-07-11

Career Henan Chemical Co

Product: 1-(METHYLAMINO)ADAMANTANE 3717-38-2
Price: US $1.00/kg
Min. Order: 1g
Purity: 99%
Supply Ability: 100KG
Release date: 2018-12-21

3717-38-2, 1-(METHYLAMINO)ADAMANTANERelated Search:

METHYLPYRIDIN-2-YLMETHYLAMINE DIHYDROCHLORIDE N-(1-ADAMANTYL)UREA N-(1-Adamantyl)acetamide FMOC-GLN(1-ADAMANTYL)-OH Amantadine 1-ADAMANTYLCYANAMIDE FMOC-GLN(1-ADAMANTYL)-P-ALKOXYBENZYL ALCOHOL RESIN 4-(1-ADAMANTYL)-3-THIOSEMICARBAZIDE ADAMANTAN-1-YL-(4-METHOXY-BENZYL)-AMINE 1-ADAMANTYLTHIOUREA N-(1-ADAMANTYL)HYDRAZINECARBOXAMIDE 1-(4-iodophenyl)-3-(1-adamantyl)guanidine tromantadine AKOS BC-0551 FMOC-GLN(1-AD)-ALKO RESIN SALOR-INT L130907-1EA N-(1-ADAMANTYL)ACRYLAMIDE AKOS BBS-00002356

N-Methyl-1-adamantyamine

N-METHYL-1-ADAMANTYLAMINE

N-Methyl-1-adamantanamine

Mrz-2/188

N-Methyl-adamantane-1-amine

N-Methyladamantanamine

N-Methyladamantine

1-(adaMantan-1-yl)-N-MethylMethanaMine

N-Methyl AdaMantylaMine

Tricyclo[3.3.1.13,7]decan-1-amine, N-methyl-

<i>N</i>-Methyl-1-adamantylamine

3717-38-2