ChemicalBook > CAS DataBase List > Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)

Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)

Product Name
Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)
CAS No.
176199-48-7
Chemical Name
Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)
Synonyms
LY 354740;Eglumetad;Eglumegad;(1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid;Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S...;Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid,2-amino-,(1S,2S,5R,6S)-;Bicyclo[3.1.0]hexane-2,6-dicarboxylicacid, 2-aMino-, [1S-(1a,2b,5a,6a)]-;Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)
CBNumber
CB61042715
Molecular Formula
C8H11NO4
Formula Weight
185.18
MOL File
176199-48-7.mol
More
Less

Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI) Property

Melting point:
270-271 °C
Boiling point:
376.4±32.0 °C(Predicted)
Density 
1.569
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
H2O : 6.33 mg/mL (34.18 mM; Need ultrasonic and warming)
form 
Powder
pka
2.06±0.40(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
5.04685
Product name
LY 354740 - CAS 176199-48-7 - Calbiochem
Packaging
10MG
Price
$156
Updated
2022/05/15
Cayman Chemical
Product number
24215
Product name
LY354740
Purity
≥95%
Packaging
1mg
Price
$33
Updated
2024/03/01
Cayman Chemical
Product number
24215
Product name
LY354740
Purity
≥95%
Packaging
5mg
Price
$106
Updated
2024/03/01
Cayman Chemical
Product number
24215
Product name
LY354740
Purity
≥95%
Packaging
10mg
Price
$160
Updated
2024/03/01
Tocris
Product number
3246
Product name
LY354740
Purity
≥98%(HPLC)
Packaging
10
Price
$208
Updated
2021/12/16
More
Less

Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI) Chemical Properties,Usage,Production

Uses

Treatment ofgeneral anxiety disorders and smoking cessation (metabotropic glutamate agonist).

Uses

LY 354740 is a highly selective and potent agonist of group II mGluR.

Definition

ChEBI: Eglumetad is a L-alpha-amino acid.

Biological Activity

Highly selective and potent agonist of group II mGlu receptors (EC 50 values are 5.1 and 24.3 nM at mGlu 2 and mGlu 3 receptors respectively and > 100000 nM at mGlu 4 , mGlu 7 , mGlu 1a and mGlu 5a receptors). Displays antianxiety and antiaddictive activity in vivo . Orally and systemically active.

storage

+4°C

Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI) Suppliers

China 54 Europe 1 India 1 United Kingdom 2 United States 12 USA 1 Global 71
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Shanghai Scientia Pharmaceutical Technology Co., Ltd.
Tel
21-21-54301573 13917723525
Fax
(86)21-51861981
Email
sales@scientiapharm.com
Country
China
ProdList
263
Advantage
62
Ascent Scientific
Tel
4401179829988
Fax
4402030 700 369
Email
customerservice@ascentscientific.co.uk
Country
United Kingdom
ProdList
279
Advantage
60
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7553
Advantage
61
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2867
Advantage
52
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3868
Advantage
58

176199-48-7, Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)Related Search:

DL-ALPHA-AMINOPIMELIC ACID Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI) L-Cyclopropylglycine L-2-Aminoadipic acid (S)-1-CYCLOPROPYLETHYLAMINE Cycloleucine (2S,1'S,2'S)-2-(CARBOXYCYCLOPROPYL)GLYCINE DL-2-METHYLGLUTAMIC ACID 1-Amino-1-cyclohexanecarboxylic acid AMINO-CYCLOPROPYL-ACETIC ACID DL-ALPHA-AMINOSUBERIC ACID D-ALPHA-AMINOSUBERIC ACID H-ALPHA-ME-LEU-OH CHEMBRDG-BB 6156098 cis-1,3-cyclohexanedicarboxylic acid 1-AMINO-3-METHYLCYCLOHEXANECARBOXYLIC ACID TALAGLUMETAD 2-AMINO-2-CYCLOPROPYLPROPIONIC ACID

  • Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)
  • Eglumegad
  • Eglumetad
  • LY 354740
  • (1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
  • Bicyclo[3.1.0]hexane-2,6-dicarboxylicacid, 2-aMino-, [1S-(1a,2b,5a,6a)]-
  • Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid,2-amino-,(1S,2S,5R,6S)-
  • Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S...
  • 176199-48-7
  • CYCLOPENTANE
  • Glutamate