Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)
- Product Name
- Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)
- CAS No.
- 176199-48-7
- Chemical Name
- Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)
- Synonyms
- LY 354740;Eglumetad;Eglumegad;(1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid;Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S...;Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid,2-amino-,(1S,2S,5R,6S)-;Bicyclo[3.1.0]hexane-2,6-dicarboxylicacid, 2-aMino-, [1S-(1a,2b,5a,6a)]-;Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)
- CBNumber
- CB61042715
- Molecular Formula
- C8H11NO4
- Formula Weight
- 185.18
- MOL File
- 176199-48-7.mol
Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI) Property
- Melting point:
- 270-271 °C
- Boiling point:
- 376.4±32.0 °C(Predicted)
- Density
- 1.569
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- solubility
- H2O : 6.33 mg/mL (34.18 mM; Need ultrasonic and warming)
- form
- Powder
- pka
- 2.06±0.40(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 5.04685
- Product name
- LY 354740 - CAS 176199-48-7 - Calbiochem
- Packaging
- 10MG
- Price
- $156
- Updated
- 2022/05/15
- Product number
- 24215
- Product name
- LY354740
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $33
- Updated
- 2024/03/01
- Product number
- 24215
- Product name
- LY354740
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $106
- Updated
- 2024/03/01
- Product number
- 24215
- Product name
- LY354740
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $160
- Updated
- 2024/03/01
- Product number
- 3246
- Product name
- LY354740
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $208
- Updated
- 2021/12/16
Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI) Chemical Properties,Usage,Production
Uses
Treatment ofgeneral anxiety disorders and smoking cessation (metabotropic glutamate agonist).
Uses
LY 354740 is a highly selective and potent agonist of group II mGluR.
Definition
ChEBI: Eglumetad is a L-alpha-amino acid.
Biological Activity
Highly selective and potent agonist of group II mGlu receptors (EC 50 values are 5.1 and 24.3 nM at mGlu 2 and mGlu 3 receptors respectively and > 100000 nM at mGlu 4 , mGlu 7 , mGlu 1a and mGlu 5a receptors). Displays antianxiety and antiaddictive activity in vivo . Orally and systemically active.
storage
+4°C
Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI) Suppliers
- Tel
- --
- Fax
- --
- info@chemstep.com
- Country
- Europe
- ProdList
- 6143
- Advantage
- 51