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Amubarvimab

Product Name
Amubarvimab
CAS No.
2509447-07-6
Chemical Name
Amubarvimab
Synonyms
Amubarvimab;Research Grade Amubarvimab;Amubarvimab (anti-Spike RBD);Research Grade Amubarvimab (DVV00311)
CBNumber
CB610617120
Formula Weight
0
MOL File
Mol file
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Amubarvimab Property

form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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Amubarvimab Chemical Properties,Usage,Production

Uses

Amubarvimab (BRII-196) is a human IgG1 mAb that bind to non-competing epitopes on the receptor binding domain (RBD) of spike protein, with a KD of 5.88 nM. Amubarvimab can effectively neutralize SARS-CoV-2 variants[1][2].

in vivo

Amubarvimab (10-50 mg/kg; i.p.) in combination with romlusevimab significantly decreases viral load in the lungs, and reduces lung pathology in a Syrian golden hamster model of SARS-CoV-2 infection[1].

References

[1] Ji Y, et, al. Preclinical characterization of amubarvimab and romlusevimab, a pair of non-competing neutralizing monoclonal antibody cocktail, against SARS-CoV-2. Front Immunol. 2022 Sep 14;13:980435. DOI:10.3389/fimmu.2022.980435
[2] Hoy SM. Amubarvimab/Romlusevimab: First Approval. Drug. 2022 Aug;82(12):1327-1331. DOI:10.1007/s40265-022-01759-3

Amubarvimab Preparation Products And Raw materials

Raw materials

Preparation Products

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Amubarvimab Suppliers

Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
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China
ProdList
71826
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60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
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QQ:2853530913
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2853530910@QQ.com
Country
China
ProdList
8000
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62
Guangzhou Hongyuan Chemical Co.,Ltd
Tel
15817493340
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981810490@qq.com
Country
China
ProdList
1566
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58
Wuhan Chemstan Biotechnology Co., Ltd.
Tel
027-65317797 15926423062
Fax
QQ:422450190
Email
422450190@qq.com
Country
China
ProdList
10308
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TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
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Biolab Reagents
Tel
027-65279366 18108604356
Email
products@biolabreagent.com
Country
China
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Wanxin Biotechnology (Jiaxing) Co., LTD
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0573-83568680 18057391398
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China
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Atagenix Laboratories
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027-87008169 17762441161
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info@atagenix.com
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AntibodySystem Laboratories SAS
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33175446423
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support@antibodysystem.com
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China
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Cell Sciences
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9785721070
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info@cellsciences.com
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China
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2509447-07-6, AmubarvimabRelated Search:


  • Amubarvimab
  • Research Grade Amubarvimab (DVV00311)
  • Research Grade Amubarvimab
  • Amubarvimab (anti-Spike RBD)
  • 2509447-07-6