L(+)-2-Amino-4-bromobutyric acid hydrobromide
- Product Name
- L(+)-2-Amino-4-bromobutyric acid hydrobromide
- CAS No.
- 15159-65-6
- Chemical Name
- L(+)-2-Amino-4-bromobutyric acid hydrobromide
- Synonyms
- (2S)-2-amino-4-bromobutanoic acid;Aminobromobutyricacidhydrobromide;L-2-AMINO-4-BROMOBUTYRIC ACID HBR;(S)-2-Amino-4-bromobutanoic acidHBr;(S)-2-Amino-4-bromobutyric acid HBr;(2S)?-?2-?AMMONIO-?4-?BROMOBUTANOATE;(S)-(+)-2-AMINO-4-BROMOBUTYRIC ACID HYD&;L(+)-2-AMINO-4-BROMOBUTYRIC ACID HYDROBROMIDE;(S)-2-AMino-4-broMobutanoic acid hydrobroMide;(2S)-2-amino-4-bromobutanoic acid hydrobromide
- CBNumber
- CB6107383
- Molecular Formula
- C4H9Br2NO2
- Formula Weight
- 262.93
- MOL File
- 15159-65-6.mol
L(+)-2-Amino-4-bromobutyric acid hydrobromide Property
- Melting point:
- 189 °C (dec.)(lit.)
- alpha
- 13 º (589nm, c=1, H2O)
- refractive index
- 17 ° (C=1, MeOH)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMF (Slightly), DMSO, Methanol (Slightly)
- form
- Solid
- color
- White to Light Brown
- optical activity
- [α]20/D +16°, c = 1 in methanol
- Stability:
- Unstable in Solution, Moisture Sensitive, Hygroscopic
- InChI
- 1S/C4H8BrNO2.BrH/c5-2-1-3(6)4(7)8;/h3H,1-2,6H2,(H,7,8);1H/t3-;/m0./s1
- InChIKey
- JDLMXICGDYZOJH-DFWYDOINSA-N
- SMILES
- Br.N[C@@H](CCBr)C(O)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 476986
- Product name
- (S)-(+)-2-Amino-4-bromobutyric acid hydrobromide
- Purity
- 97%
- Packaging
- 1g
- Price
- $118
- Updated
- 2026/03/19
- Product number
- A1450
- Product name
- (S)-(+)-2-Amino-4-bromobutyric Acid Hydrobromide
- Purity
- >98.0%(N)(T)
- Packaging
- 1g
- Price
- $71
- Updated
- 2026/03/19
- Product number
- A1450
- Product name
- (S)-(+)-2-Amino-4-bromobutyric Acid Hydrobromide
- Purity
- >98.0%(N)(T)
- Packaging
- 5g
- Price
- $242
- Updated
- 2026/03/19
- Product number
- A602465
- Product name
- (S)-(+)-2-Amino-4-bromobutyricAcidHydrobromide(~90%)
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- A602465
- Product name
- (S)-(+)-2-Amino-4-bromobutyricAcidHydrobromide(~90%)
- Packaging
- 2.5g
- Price
- $390
- Updated
- 2021/12/16
L(+)-2-Amino-4-bromobutyric acid hydrobromide Chemical Properties,Usage,Production
Chemical Properties
white to light beige powder
Uses
(S)-(+)-2-Amino-4-bromobutyric acid hydrobromide may be used in the synthesis of metalloaminoacids such as [34S]-enriched methionine (34S-Met), telluromethionine (TeMet) and selenohomolanthionine (SeHLan).
Synthesis
2185-03-7
15159-65-6
The general procedure for the synthesis of L(+)-2-amino-4-bromobutyric acid hydrobromide from L-homoserine lactone hydrochloride is as follows: Example 14: Compound 322 ((2R,6S,13aS,14aR,16aS,Z)-6-(tert-butoxycarbonylamino)-14a-(2,5-dichlorothiophene-3-ylsulfonylcarbamoyl)-5,16-dioxo-2,3,5,6,7,8,10,11,13a,14,14a,15,16,16a-tetradecahydro- 1H-cyclopropan[e]pyrrolo[1,2:1,6,9]oxadiazole cyclopentadien-2-yl)4-chloroisoindole-2-carboxylate) was prepared as follows: Step 1: Synthesis of (-S)-2-amino-4-bromobutyric acid hydrobromide 3-Aminodihydrofuran-2(3H)-one hydrochloride (10.30 g, 74.87 mmol) was dissolved in 58 mL of a 30% w/w HBr solution of acetic acid and the reaction was stirred at 65 °C for 30 hrs. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The resulting solid was suspended in methyl tert-butyl ether (MTBE, 200 mL) and stirred for 30 minutes. The solid was collected by filtration, washed with MTBE (200 mL) and dried to give the target product (98% yield). Product characterization: 1H NMR (400 MHz, DMSO-d6) δ 8.37 (s, 3H), 4.01 (m, 1H), 3.65 (m, 2H), 2.33 (m, 2H).
References
[1] Journal of Medicinal Chemistry, 2014, vol. 57, # 5, p. 1753 - 1769
[2] Patent: WO2008/137779, 2008, A2. Location in patent: Page/Page column 158-160
[3] Organic Letters, 2008, vol. 10, # 24, p. 5521 - 5524
[4] Tetrahedron, 1985, vol. 41, # 10, p. 1833 - 1845
[5] Journal of Organic Chemistry, 2008, vol. 73, # 1, p. 168 - 176
L(+)-2-Amino-4-bromobutyric acid hydrobromide Preparation Products And Raw materials
Raw materials
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View Lastest Price from L(+)-2-Amino-4-bromobutyric acid hydrobromide manufacturers
- Product
- (S)-(+)-2-AMino-4-broMobutyric Acid HydrobroMide 15159-65-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- 50kgs/month
- Release date
- 2021-11-20
- Product
- (S)-(+)-2-Amino-4-bromobutyric acid hydrobromide 15159-65-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.5%
- Supply Ability
- 100 tons
- Release date
- 2022-02-08
- Product
- L(+)-2-Amino-4-bromobutyric acid hydrobromide 15159-65-6
- Price
- US $1.00/g
- Min. Order
- 100g
- Purity
- 99%
- Supply Ability
- G/KG/T
- Release date
- 2019-12-20