Miltrione

Product Name: Miltrione
CAS No.: 27210-57-7
Chemical Name: Miltrione
Synonyms: Rosmariquinone;C13715;Miltiron;NSC 639662;minestrone;Miltrione USP/EP/BP;8,8-DIMETHYL-2-PROPAN-2-YL-6,7-DIHYDRO-5H-PHENANTHRENE-3,4-DIONE;5,6,7,8-Tetrahydro-2-isopropyl-8,8-diMethyl-3,4-phenanthrenedione;5,6,7,8-Tetrahydro-8,8-dimethyl-2-isopropyl-3,4-phenanthrenedione;2-Isopropyl-5,6,7,8-tetrahydro-8,8-dimethylphenanthrene-3,4-dione
CBNumber: CB61074910
Molecular Formula: C19H22O2
Formula Weight: 282.38
MOL File: 27210-57-7.mol

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Miltrione Property

Melting point:: 98-100℃ (hexane )
Boiling point:: 421.6±45.0 °C(Predicted)
Density: 1.094±0.06 g/cm3 (20 ºC 760 Torr)
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: powder
color: Red
LogP: 4.916 (est)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: M344500
Product name: Miltirone
Packaging: 2.5mg
Price: $145
Updated: 2021/12/16

TRC

Product number: M344500
Product name: Miltirone
Packaging: 25mg
Price: $1205
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FM26008
Product name: Miltirone
Packaging: 1mg
Price: $120
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FM26008
Product name: Miltirone
Packaging: 2mg
Price: $200
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0026123
Product name: MILTIRONE
Purity: 95.00%
Packaging: 10MG
Price: $367.5
Updated: 2021/12/16

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Miltrione Chemical Properties,Usage,Production

Chemical Properties

Orange granular crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Salvia miltiorrhiza.

Uses

An active component in Salvia miltiorrhiza that has been shown to inhibit the increase in the abundance of the mRNA for the α4 subunit of the GABAA receptor induced by ethanol withdrawal in cultured hippocampal neurons. A potential phytotherapeutic agent in the treatment of alcohol dependence.

Definition

ChEBI: Miltirone is an abietane diterpenoid.

in vivo

Miltirone (10-60 mg/kg, p.o.; one hour before test) increases the number of punished crossings in the four-plate test in mice^[1].

Animal Model:	Mice^[1]
Dosage:	10, 30, 60 mg/kg
Administration:	Oral gavage (p.o.); an hour before test
Result:	Increased the number of punished crossings of mice in the 'Four-Plate Test'. Showed some reversal of the effect of diazepam as expected for a partial agonist. Produced no muscle relaxant effect and did not impair the performance of mice in the Julou-Courvoisier horizontal wire test.

IC 50

CES2: 0.04 μM (Ki)

Miltrione Preparation Products And Raw materials

Raw materials

Preparation Products

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Miltrione Suppliers

Canada 2 China 121 Germany 1 India 2 United Kingdom 2 United States 8 USA 1 Global 137

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Shanghai Winherb Medical Technology Co., Ltd.

Tel: 021-38218169 13341702378
Fax: QQ：190129269
Email: winherb@126.com
Country: China
ProdList: 1245
Advantage: 58

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9546
Advantage: 55

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

Cheng Du Pufeide Biotechnology Co., Ltd.

Tel: 028-82610909 13388174823
Fax: 8171-1798
Email: scglp@glp-china.com
Country: China
ProdList: 1064
Advantage: 58

Shanghai BeiZhuo Biotech Co., Ltd.

Tel: 021-61119791,13386096464
Fax: 021-50190009
Email: bzswkf@foxmail.com
Country: China
ProdList: 3921
Advantage: 50

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

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View Lastest Price from Miltrione manufacturers

Career Henan Chemical Co

Product: Miltrione 27210-57-7
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-16

27210-57-7, MiltrioneRelated Search:

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5,6,7,8-Tetrahydro-2-isopropyl-8,8-diMethyl-3,4-phenanthrenedione

5,6,7,8-Tetrahydro-8,8-diMethyl-2-(1-Methylethyl)-3,4-phenanthrenedione

2-Isopropyl-5,6,7,8-tetrahydro-8,8-dimethylphenanthrene-3,4-dione

5,6,7,8-Tetrahydro-8,8-dimethyl-2-isopropyl-3,4-phenanthrenedione

Rosmariquinone

C13715

Miltiron

NSC 639662

3,4-Phenanthrenedione,5,6,7,8-tetrahydro-8,8-dimethyl-2-(1-methylethyl)-

8,8-DIMETHYL-2-PROPAN-2-YL-6,7-DIHYDRO-5H-PHENANTHRENE-3,4-DIONE

Miltrione USP/EP/BP

minestrone

2-Isopropyl-8,8-dimethyl-5,6,7,8-tetrahydrophenanthrene-3,4-dione

Gamma-aminobutyric acid Receptor,inhibit,acid,γ-Aminobutyric acid Receptor,GABA Receptor,neurotransmission,Miltirone,GABA,γ-aminobutyric,Inhibitor

27210-57-7

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