2-HYDROXY-3-AMINO-5-PICOLINE
- Product Name
- 2-HYDROXY-3-AMINO-5-PICOLINE
- CAS No.
- 52334-51-7
- Chemical Name
- 2-HYDROXY-3-AMINO-5-PICOLINE
- Synonyms
- Finerenone SM3-03;Guaiacol Impurity 30;3-Amino-5-methyl-2-pyridone;3-amino-5-methylpyridin-2-ol;2-HYDROXY-3-AMINO-5-PICOLINE;3-AMino-5-Methylpyridin-2(1H)-one;3-AMino-2-hydroxy-5-Methylpyridine;2(1H)-Pyridinone, 3-amino-5-methyl-;2-HYDROXY-3-AMINO-5-PICOLINE ISO 9001：2015 REACH
- CBNumber
- CB61076101
- Molecular Formula
- C6H8N2O
- Formula Weight
- 124.14
- MOL File
- 52334-51-7.mol
2-HYDROXY-3-AMINO-5-PICOLINE Property
- Melting point:
- 119-120℃
- Boiling point:
- 337℃
- Density
- 1.137
- Flash point:
- 158℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 14.28±0.10(Predicted)
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A576773
- Product name
- 3-Amino-2-hydroxy-5-methylpyridine
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 081264
- Product name
- 3-Amino-5-methylpyridin-2-ol
- Purity
- 95%
- Packaging
- 1g
- Price
- $19
- Updated
- 2021/12/16
- Product number
- 081264
- Product name
- 3-Amino-5-methylpyridin-2-ol
- Purity
- 95%
- Packaging
- 5g
- Price
- $49
- Updated
- 2021/12/16
- Product number
- J56686
- Product name
- 3-Amino-2-hydroxy-5-methylpyridine
- Packaging
- 100g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- CHM0078926
- Product name
- 3-AMINO-2-HYDROXY-5-PICOLINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $788.29
- Updated
- 2021/12/16
2-HYDROXY-3-AMINO-5-PICOLINE Chemical Properties,Usage,Production
Synthesis
7464-14-4
52334-51-7
Example 102A. Synthesis of 3-amino-5-methylpyridin-2-ol: 5-methyl-3-nitropyridin-2-ol (50 mg, 0.32 mmol) was dissolved in methanol (5 mL) and ammonium chloride (174 mg, 3.24 mmol) and zinc powder (106 mg, 1.62 mmol) were added sequentially. The reaction mixture was stirred at room temperature for 1 h, during which a color change was observed. After completion of the reaction, the suspension was removed by filtration and the filter cake was washed with methanol. The filtrates were combined and concentrated under reduced pressure to remove the solvent. The crude product was purified by grinding with a solvent mixture of methanol and ethyl acetate (1:1, v/v). After filtration, the solvent was removed under reduced pressure to afford the target compound 3-amino-5-methylpyridin-2-ol (16 mg, 0.13 mmol, 40% yield). The product was characterized by NMR hydrogen spectroscopy (400 MHz, MeOD): δ 2.03 (s, 3H), 6.56 (s, 1H), 6.63 (s, 1H).
References
[1] Patent: WO2014/22343, 2014, A1. Location in patent: Paragraph 00265
[2] Journal of the American Chemical Society, 1950, vol. 72, p. 2806
[3] Journal of the American Chemical Society, 1957, vol. 79, p. 3552
[4] Patent: EP2471792, 2012, A1. Location in patent: Page/Page column 43
2-HYDROXY-3-AMINO-5-PICOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-HYDROXY-3-AMINO-5-PICOLINE manufacturers
- Product
- 2-HYDROXY-3-AMINO-5-PICOLINE 52334-51-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-30
- Product
- 2-HYDROXY-3-AMINO-5-PICOLINE 52334-51-7
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 2-HYDROXY-3-AMINO-5-PICOLINE 52334-51-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-09-26