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Omethoate

Product Name
Omethoate
CAS No.
1113-02-6
Chemical Name
Omethoate
Synonyms
S6876;s-6876;MODERN;B-45432;FOLIMAT;OMETHOAT;ent25,776;P=O-Rogor;bay 45432;OMETHOATE
CBNumber
CB6109938
Molecular Formula
C5H12NO4PS
Formula Weight
213.19
MOL File
1113-02-6.mol
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Omethoate Property

Melting point:
-27.9°C
Boiling point:
135°C
Density 
1.3200
vapor pressure 
3.3×10-3Pa (20 °C)
Flash point:
100 °C
storage temp. 
0-6°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Water Solubility 
Miscible
pka
14.40±0.46(Predicted)
form 
liquid
BRN 
1785256
Stability:
Hygroscopic
CAS DataBase Reference
1113-02-6(CAS DataBase Reference)
NIST Chemistry Reference
Omethoate(1113-02-6)
EPA Substance Registry System
Omethoate (1113-02-6)
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Safety

Hazard Codes 
T+;N,N,T+,T
Risk Statements 
21-25-50
Safety Statements 
1/2-23-36/37-45-61
RIDADR 
3018
WGK Germany 
3
RTECS 
TF8050000
HazardClass 
6.1(a)
PackingGroup 
II
HS Code 
29309090
Hazardous Substances Data
1113-02-6(Hazardous Substances Data)
Toxicity
LD50 oral in rabbit: 50mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H311Toxic in contact with skin

H400Very toxic to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
36181
Product name
Omethoate
Purity
PESTANAL
Packaging
100mg
Price
$72.3
Updated
2024/03/01
TRC
Product number
O635500
Product name
Omethoate
Packaging
100mg
Price
$55
Updated
2021/12/16
TRC
Product number
O635500
Product name
Omethoate
Packaging
1g
Price
$385
Updated
2021/12/16
AHH
Product number
MT-57501
Product name
Omethoate
Purity
98%
Packaging
1g
Price
$470
Updated
2021/12/16
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Omethoate Chemical Properties,Usage,Production

Uses

Omethoate is a systemic insecticide used for the control of (mostly) sucking insects and mites in a wide variety of crops.

Uses

Insecticidal, acaricidal, and fungicidal combinations of carboxamides and other pesticides.

Definition

ChEBI: Omethoate is an organic thiophosphate and an organothiophosphate insecticide. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an acaricide and an agrochemical. It is functionally related to a N-methyl-2-sulfanylacetamide.

Contact allergens

Contact dermatitis from omethoate-dimethoxon is rare.

Metabolic pathway

Omethoate is the P=O analogue (oxon) of dimethoate. Dimethoate is metabolised via oxidative desulfuration to omethoate which is the active anti-acetylcholinesterase metabolite. This biotransformation occurs in all media: hence the metabolic pathways of both compounds have much in common. However, degradative pathways acting directly on dimethoate such as O-demethylation, N-demethylation and hydrolysis of the amide function mean that the balance between activation and degradative metabolism will influence their respective selective toxicities. In mammals there are two main routes of degradation: (i) glutathione transferase mediated O-demethylation (ii) hydrolysis to N-methylthioglycolamide which is S-methylated by S-adenosylmethionine and subsequently thiooxidised. In soil and plants the N-methylthioglycolamide moiety formed from the hydrolysis of omethoate undergoes a complex series of C1, C2 and C3 biotransformations ultimately leading to oxalate and citrate respectively and total degradation to C02. The information reported below is derived largely from an evaluation prepared by the UK MAFF Pesticide Safety Directorate (PSD, 1993).

Metabolism

Orally administered omethoate to rats is rapidly metabolized and excreted in the urine; the main metabolites are O-demethylomethoate and N-methyl-2- methylsulfinylacetamide. O-Demethylation and hydrolysis of the P?S bond are main degradation routes both in mammals and plants. Omethoate is rapidly degraded in soils with DT50 of a few days.

Degradation

Omethoate was slowly hydrolysed in acidic media but more rapidly under alkaline conditions. The half-lives for hydrolysis at pH 4,7, and 9 were 102 days, 17 days and 28 hours, respectively (PM). Omethoate does not absorb light at wavelengths above 250 nm and it is thus unlikely to be subject to photodecomposition. An aqueous solution of omethoate was irradiated for 14 hours with a high pressure filtered mercury vapour lamp without detectable photolysis occurring (PSD, 1993).

Toxicity evaluation

The acute oral LD50 for rats is about 25 mg/kg. Inhalation LC50 (4 h) for rats is 0.3 mg/L air. ADI is 0.3 μg/kg b.w.

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Omethoate Suppliers

1113-02-6, OmethoateRelated Search:


  • Omethoate E.C.,penetrating
  • omethoatge
  • B-45432
  • O,O-dimethyl S-methylcarbamoylmethyl phosphorothioate,omethoate (ISO)
  • Omethoate Standard
  • 2-(dimethoxyphosphorylthio)-N-methyl-acetamide
  • 2-dimethoxyphosphorylsulfanyl-N-methylacetamide
  • 2-dimethoxyphosphorylsulfanyl-N-methyl-ethanamide
  • Folimat Dimethoate-met
  • Omethoate Solution, 1000ppm
  • Omethoate Solution, 100ppm
  • 2-dimethoxyphosphinoylthio-n-methylacetamide
  • Acetamide, 2-mercapto-N-methyl-, S-ester with O,O-dimethyl phosphorothioate
  • acetamide,2-mercapto-n-methyl-,s-esterwitho,o-dimethylphosphorothioate
  • BAYER 45,432
  • Bayer 45432
  • bayer45,432
  • bayers-6876
  • Dimethoate Oxygen analog
  • Dimethoate PO isologue
  • Dimethoate-met
  • dimethoateoxygenanalog
  • dimethoatepoisologue
  • dimethoxane(omethoate)
  • Dimethyl-S-(N-methyl-carbamoyl-methyl)phosphorothiolate
  • ENT 25,776
  • ent25,776
  • Folimat 4E
  • imethoate oxon
  • O,O-Dimethyl S-(2-(methylamino)-2-oxoethyl)phosphorothioate
  • O,O-Dimethyl S-(N-methylcarbamoylmethyl) phosphorothiolate
  • O,O-Dimethyl S-(N-methylcarbamoylmethyl) thiophosphate
  • o,o-Dimethyl S-[2-(methylamino)-2-oxoethyl] thiophosphate
  • o,o-dimethylphosphorothioates-esterwith2-mercapto-n-methylacetamide
  • O,O-Dimethyl-S-((N-methyl-carbamoyl)-methyl)-monothiofosfaat
  • o,o-dimethyls-(2-(methylamino)-2-oxoethyl)phosphorothioate
  • O,O-Dimethyl-S-(2-oxo-3-azabutyl)-monothiophosphate
  • O,O-Dimethyl-S-(N-methylaminoformylmethyl)phosphorothioate
  • o,o-dimethyl-s-(n-methyl-carbamoyl)-methyl-monothiophosphat
  • O,O-Dimethyl-S-(N-methyl-carbamoyl)-methyl-monothiophosphate
  • o,o-dimethyls-(n-methylcarbamoylmethyl)phosphorothiolate
  • o,o-dimethyl-s-(n-methyl-carbamoyl-methyl)-thiolphosphat
  • O,O-Dimethyl-S-(N-methyl-carbamoyl-methyl)-thiolphosphate
  • o,o-dimethyls-(n-methylcarbamoylmethyl)thiophosphate
  • O,O-Dimethyl-S-[2-(methylamino)-2-oxoethyl]phosphorothioate
  • O,O-Dimetil-S-(N-metil-carbamoil)-metil-monotiofosfato
  • O-Analog of dimethoate
  • o-analogofdimethoate
  • P=O-Rogor
  • Phosphorothioic acid, O,O-dimethyl ester, S-ester with 2-mercapto-N-methylacetamide
  • Phosphorothioicacid,esters,O,O-dimethyl-S-[2(methylamino)-2-oxoethyl]ester
  • phosphorothioicacid,o,o-dimethylester,s-esterwith2-mercapto-n-methylaceta
  • PO-Dimethoate
  • S6876
  • s-6876
  • Thiophosphate de O,O-dimethyle et de S-(N-methylcarbamoyl) methyle
  • thiophosphatedeo,o-dimethyleetdes-(n-methylcarbamoyl)methyle
  • bay 45432