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Sodium orthovanadate

Product Name
Sodium orthovanadate
CAS No.
13721-39-6
Chemical Name
Sodium orthovanadate
Synonyms
SODIUM VANADATE;Sodium orthavanadium;Sodium Orthovanadate(Ⅴ);sodiumvanadate(v)(na3vo4);trisodium tetraoxovanadate;DECAVANDATE;trisodiumvanadate;SODIUM O-VANADATE;Is sodium vanadate;Pervanadate(100mM)
CBNumber
CB6111122
Molecular Formula
Na3VO4
Formula Weight
183.91
MOL File
13721-39-6.mol
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Sodium orthovanadate Property

Melting point:
850-866 °C(lit.)
storage temp. 
Sealed in dry,Room Temperature
solubility 
H2O: soluble
form 
Solid
color 
off-white
biological source
synthetic (organic)
Water Solubility 
soluble
Exposure limits
NIOSH: Ceiling 0.05 mg/m3
Stability:
Stable. Incompatible with strong oxidizing agents.
InChI
InChI=1S/3Na.4O.V
InChIKey
HQHUIUQMQXUPHI-UHFFFAOYSA-N
SMILES
[V](=O)(O[Na])(O[Na])O[Na]
CAS DataBase Reference
13721-39-6(CAS DataBase Reference)
EPA Substance Registry System
Sodium vanadium oxide (Na3VO4) (13721-39-6)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
Safety Statements 
22-36
RIDADR 
UN3285
WGK Germany 
3
RTECS 
YW1120000
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
28419030
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
567540
Product name
Sodium Orthovanadate - CAS 13721-39-6 - Calbiochem
Purity
A broad spectrum potent inhibitor of protein tyrosine phosphatases.
Packaging
5G
Price
$73.3
Updated
2025/07/31
Sigma-Aldrich
Product number
450243
Product name
Sodium orthovanadate
Purity
99.98% trace metals basis
Packaging
10g
Price
$77.4
Updated
2025/07/31
Sigma-Aldrich
Product number
450243
Product name
Sodium orthovanadate
Purity
99.98% trace metals basis
Packaging
50g
Price
$207
Updated
2025/07/31
Sigma-Aldrich
Product number
S6508
Product name
Sodium orthovanadate
Purity
≥90% (titration)
Packaging
10g
Price
$40.4
Updated
2025/07/31
Sigma-Aldrich
Product number
S6508
Product name
Sodium orthovanadate
Purity
≥90% (titration)
Packaging
50g
Price
$138
Updated
2025/07/31
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Sodium orthovanadate Chemical Properties,Usage,Production

Chemical Properties

It forms colourless hexagonal columnar crystals that are soluble in water but insoluble in ethanol.

Uses

Sodium orthovanadate (Na3VO4) can be used as a metal precursor in the synthesis of:
Vanadium-MCM-48 (V-MCM-48) by anion-exchange method. V-MCM-48 is used as a catalyst in oxidation of styrene to benzaldehyde.
Nanorods of vanadium oxide particles by glycothermal method.
Yttrium vanadate (YVO4) doped with colloidal europium.

Uses

Sodium Orthovanadate is an inhibitor of several phosphatases and kinases. General inhibitor of tyrosine phosphatases, a large family of enzymes that catalyze the removal of phosphate groups from tyrosine residues.

Definition

ChEBI: Trisodium vanadate is an inorganic sodium salt of formula Na3VO4 containing the tetrahedral VO4(3-) It has a role as an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor, a radiation protective agent, an apoptosis inducer and an antineoplastic agent. It contains a vanadate(3-).

Preparation

Sodium orthovanadate is produced by dissolving vanadium(V) oxide in a solution of sodium hydroxide:
V2O5 + 6 NaOH → 2 Na3VO4 + 3 H2O
The salt features tetrahedral VO3-4 anion centers linked to octahedral Na+ cation sites.

Hazard

Poison by ingestion.

reaction suitability

reagent type: catalyst
core: vanadium

Biological Activity

Inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases.

Biochem/physiol Actions

Sodium orthovandate suppresses the activation of p53-mediated apoptosis triggered in response to radiation. It reduces the detrimental effects of hematopoietic syndrome, hematopoiesis and delayed genotoxic effects of induced by total body irradiation of mice.24 In combination with menadione, orthovandate prevents the migration of detached human glioma cells in response to anti-cancer drugs.25

Safety Profile

Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of VOx and NazO. See also VANADIUM COMPOUNDS.

storage

Store at RT

Sodium orthovanadate Preparation Products And Raw materials

Raw materials

Preparation Products

Ammonium metavanadate
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View Lastest Price from Sodium orthovanadate manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Sodium orthovanadate 13721-39-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-12-03
Hebei Yanxi Chemical Co., Ltd.
Product
Sodium Orthovanadate 13721-39-6
Price
US $50.00/Kg/Drum
Min. Order
25KG
Purity
99%min
Supply Ability
100tons/month
Release date
2020-07-06
Zhuozhou Wenxi import and Export Co., Ltd
Product
Sodium orthovanadate 13721-39-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

13721-39-6, Sodium orthovanadateRelated Search:

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  • 13721-39-6
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  • Kinase/Phosphatase Biology
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