Darunavir-D9

Product Name: Darunavir-D9
CAS No.: 1133378-37-6
Chemical Name: Darunavir-D9
Synonyms: TMC-114-d9;UIC-94017-d9;Darunavir-D9;[2H9]-Darunavir;Nebramine Impurity 2;Darunavir-d9;Darunavir-d9 (iso-butyl-d9);[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl-d9)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester;[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl-d9)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-β]-furan-3-yl Ester;Darunavir D9Q: What is Darunavir D9 Q: What is the CAS Number of Darunavir D9 Q: What is the storage condition of Darunavir D9 Q: What are the applications of Darunavir D9
CBNumber: CB61121362
Molecular Formula: C27H37N3O7S
Formula Weight: 547.66358
MOL File: 1133378-37-6.mol

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Darunavir-D9 Property

Melting point:: 74-760C
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
color: Off-White to Pale Beige

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 25220
Product name: Darunavir-d9
Purity: ≥99% deuterated forms (d1-d9)
Packaging: 1mg
Price: $517
Updated: 2024/03/01

TRC

Product number: D193502
Product name: Darunavir-d9
Packaging: 1mg
Price: $275
Updated: 2021/12/16

Usbiological

Product number: D1078-05
Product name: Darunavir-d9
Packaging: 1mg
Price: $566
Updated: 2021/12/16

TRC

Product number: D193502
Product name: Darunavir-d9
Packaging: 10mg
Price: $2180
Updated: 2021/12/16

AK Scientific

Product number: 5497DC
Product name: Darunavir-d9
Packaging: 1mg
Price: $673
Updated: 2021/12/16

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Darunavir-D9 Chemical Properties,Usage,Production

Description

Darunavir-d₉ is intended for use as an internal standard for the quantification of darunavir (Item Nos. 15866 | 31083) by GC- or LC-MS. Darunavir is an HIV-1 protease inhibitor. It is active against HIV-1_LAI in MT-2 cells (IC₅₀ = 3 nM) with a cytotoxic concentration (CC₅₀) of 74.4 μM. Darunavir is also active against wild-type and multidrug-resistant clinical isolates of HIV-1 in phytohemagglutinin-activated peripheral blood mononuclear cells (PHA-PBMCs; IC₅₀s = 3 and 3-29 nM, respectively). It inhibits cell-free diffusion and cell-to-cell spread of HIV-1 in Jurkat cell populations (IC₅₀s = 2.5 and 2.8 nM, respectively). Formulations containing darunavir have been used in combination therapy for the treatment of HIV.

Chemical Properties

Off-White Amorphous Solid

Uses

Second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. It is a COVID19-related research product.

Uses

Darunavir-D9 can be intended for use as an internal standard for the quantification of Darunavir by GC- or LC-mass spectrometry.

Uses

Darunavir-D9 can be used as second generation HIV-1-protease inhibitor; structurally similar to amprenavir.

Darunavir-D9 Preparation Products And Raw materials

Raw materials

Preparation Products

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Darunavir-D9 Suppliers

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1133378-37-6, Darunavir-D9Related Search:

Darunavir

Darunavir-d<sub>9</sub>

Darunavir-D9

[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl-d9)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester

TMC-114-d9

UIC-94017-d9

[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl-d9)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-β]-furan-3-yl Ester

Darunavir-d9 (iso-butyl-d9)

[2H9]-Darunavir

Darunavir D9Q: What is Darunavir D9 Q: What is the CAS Number of Darunavir D9 Q: What is the storage condition of Darunavir D9 Q: What are the applications of Darunavir D9

Nebramine Impurity 2

1133378-37-6

Intermediates & Fine Chemicals

Isotope Labeled Compounds

Pharmaceuticals

Aromatics

Heterocycles

Inhibitors

Isotope Labelled Compounds