Darunavir-D9
- Product Name
- Darunavir-D9
- CAS No.
- 1133378-37-6
- Chemical Name
- Darunavir-D9
- Synonyms
- TMC-114-d9;UIC-94017-d9;Darunavir-D9;[2H9]-Darunavir;Nebramine Impurity 2;Darunavir-d9;Darunavir-d9 (iso-butyl-d9);[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl-d9)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester;[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl-d9)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-β]-furan-3-yl Ester;Darunavir D9Q: What is Darunavir D9 Q: What is the CAS Number of Darunavir D9 Q: What is the storage condition of Darunavir D9 Q: What are the applications of Darunavir D9
- CBNumber
- CB61121362
- Molecular Formula
- C27H37N3O7S
- Formula Weight
- 547.66358
- MOL File
- 1133378-37-6.mol
Darunavir-D9 Property
- Melting point:
- 74-760C
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- color
- Off-White to Pale Beige
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 25220
- Product name
- Darunavir-d9
- Purity
- ≥99% deuterated forms (d1-d9)
- Packaging
- 1mg
- Price
- $517
- Updated
- 2024/03/01
- Product number
- D193502
- Product name
- Darunavir-d9
- Packaging
- 1mg
- Price
- $275
- Updated
- 2021/12/16
- Product number
- D1078-05
- Product name
- Darunavir-d9
- Packaging
- 1mg
- Price
- $566
- Updated
- 2021/12/16
- Product number
- D193502
- Product name
- Darunavir-d9
- Packaging
- 10mg
- Price
- $2180
- Updated
- 2021/12/16
- Product number
- 5497DC
- Product name
- Darunavir-d9
- Packaging
- 1mg
- Price
- $673
- Updated
- 2021/12/16
Darunavir-D9 Chemical Properties,Usage,Production
Description
Darunavir-d9 is intended for use as an internal standard for the quantification of darunavir (Item Nos. 15866 | 31083) by GC- or LC-MS. Darunavir is an HIV-1 protease inhibitor. It is active against HIV-1LAI in MT-2 cells (IC50 = 3 nM) with a cytotoxic concentration (CC50) of 74.4 μM. Darunavir is also active against wild-type and multidrug-resistant clinical isolates of HIV-1 in phytohemagglutinin-activated peripheral blood mononuclear cells (PHA-PBMCs; IC50s = 3 and 3-29 nM, respectively). It inhibits cell-free diffusion and cell-to-cell spread of HIV-1 in Jurkat cell populations (IC50s = 2.5 and 2.8 nM, respectively). Formulations containing darunavir have been used in combination therapy for the treatment of HIV.
Chemical Properties
Off-White Amorphous Solid
Uses
Second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. It is a COVID19-related research product.
Uses
Darunavir-D9 can be intended for use as an internal standard for the quantification of Darunavir by GC- or LC-mass spectrometry.
Uses
Darunavir-D9 can be used as second generation HIV-1-protease inhibitor; structurally similar to amprenavir.
Darunavir-D9 Preparation Products And Raw materials
Raw materials
Preparation Products
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