Pimonidazole

Product Name: Pimonidazole
CAS No.: 70132-50-2
Chemical Name: Pimonidazole
Synonyms: NSC 380540;Pimonidazole;Pimonidazole USP/EP/BP;inhibit,Pimonidazole,Inhibitor;1-(2-nitroimidazol-1-yl)-3-piperidin-1-ylpropan-2-ol;alpha-((2-Nitroimidazol-1-yl)methyl)-1-piperidineethanol;α-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol;1-(2-Nitro-1H-imidazol-1-yl)-3-(piperidin-1-yl)propan-2-ol;1-Piperidineethanol, α-[(2-nitro-1H-imidazol-1-yl)methyl]-;1-(2-Nitro-1H-imidazol-1-yl)-3-(piperidin-1-yl)-2-propanol
CBNumber: CB61179505
Molecular Formula: C11H18N4O3
Formula Weight: 254.29
MOL File: 70132-50-2.mol

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Pimonidazole Property

Melting point:: 110-113°C
Boiling point:: 490.5±55.0 °C(Predicted)
Density: 1.39±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: >20mg/mL
pka: 14.06±0.20(Predicted)
form: powder
color: yellow

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Safety

Hazard Codes: Xn
Risk Statements: 22

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N1165
Product name: Pimonidazole
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $168
Updated: 2024/03/01

Sigma-Aldrich

Product number: N1165
Product name: Pimonidazole
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $405
Updated: 2024/03/01

Cayman Chemical

Product number: 89130
Product name: Pimonidazole
Purity: ≥98%
Packaging: 5mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 89130
Product name: Pimonidazole
Purity: ≥98%
Packaging: 10mg
Price: $61
Updated: 2024/03/01

Cayman Chemical

Product number: 89130
Product name: Pimonidazole
Purity: ≥98%
Packaging: 50mg
Price: $243
Updated: 2024/03/01

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Pimonidazole Chemical Properties,Usage,Production

Description

Hypoxic cells are low oxygen cells that when present in tumors are radioresistant and chemoresistant. Pimonidazole is a small molecule radiosensitizer that has proven to be an effective and nontoxic hypoxia marker for human squamous cell carcinomas of the cervix, head, and neck. This immunochemical hypoxia marker has been widely used in experimental and clinical studies due to its chemical stability, water solubility, and wide tissue distribution. It is generally administered in aqueous solution by injection.

Uses

Pimonidazole is an effective and nontoxic hypoxia detection reagent. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids. It labels hypoxic tumor cells in vivo. Also labels hypoxic mesenchymal stem cells in mouse bone marrow.

Biochem/physiol Actions

Pimonidazole is an effective and nontoxic exogenous 2-nitroimidazole hypoxia marker. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids.

storage

Store at -20°C

Pimonidazole Preparation Products And Raw materials

Raw materials

Preparation Products

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Pimonidazole Suppliers

China 25 United Kingdom 1 United States 5 Global 31

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 4602
Advantage: 55

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-029-89586680 +86-18192503167
Fax: +86-29-88380327
Email: 1026@dideu.com
Country: China
ProdList: 7724
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30240
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11217
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

Hubei Wande Chemical Co., Ltd

Tel: 027-59210159 15377098680
Fax: 027-59210159
Email: 1148280011@qq.com
Country: China
ProdList: 9961
Advantage: 58

70132-50-2, PimonidazoleRelated Search:

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Pimonidazole

1-(2-Nitro-1H-imidazol-1-yl)-3-(piperidin-1-yl)-2-propanol

α-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol

alpha-((2-Nitroimidazol-1-yl)methyl)-1-piperidineethanol

alpha-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol

NSC 380540

1-(2-nitroimidazol-1-yl)-3-piperidin-1-ylpropan-2-ol

1-Piperidineethanol, α-[(2-nitro-1H-imidazol-1-yl)methyl]-

Pimonidazole USP/EP/BP

inhibit,Pimonidazole,Inhibitor

1-(2-Nitro-1H-imidazol-1-yl)-3-(piperidin-1-yl)propan-2-ol

70132-50-2