ChemicalBook > CAS DataBase List > Tolimidone

Tolimidone

Product Name
Tolimidone
CAS No.
41964-07-2
Chemical Name
Tolimidone
Synonyms
MLR 1023;100568;CP-26154;CID-39065;NSC 314335;Tolimidone;Tolimidone (MLR-1023);MLR 1023 - Tolimidone | CP 26154;5-(m-Tolyloxy)pyrimidin-2(1H)-one;5-(3-Methylphenoxy)-2(1H)-pyrimidinone
CBNumber
CB61179954
Molecular Formula
C11H10N2O2
Formula Weight
202.21
MOL File
41964-07-2.mol
More
Less

Tolimidone Property

Melting point:
163-164℃
Density 
1.22
storage temp. 
room temp
solubility 
DMSO: soluble15mg/mL (clear solution)
form 
powder
pka
8.14±0.10(Predicted)
color 
white to beige
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0371
Product name
MLR-1023
Purity
≥98% (HPLC)
Packaging
5mg
Price
$97.9
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0371
Product name
MLR-1023
Purity
≥98% (HPLC)
Packaging
25mg
Price
$380
Updated
2024/03/01
Cayman Chemical
Product number
21496
Product name
MLR-1023
Purity
≥95%
Packaging
5mg
Price
$50
Updated
2024/03/01
Cayman Chemical
Product number
21496
Product name
MLR-1023
Purity
≥95%
Packaging
10mg
Price
$89
Updated
2024/03/01
Cayman Chemical
Product number
21496
Product name
MLR-1023
Purity
≥95%
Packaging
25mg
Price
$209
Updated
2024/03/01
More
Less

Tolimidone Chemical Properties,Usage,Production

Description

MLR-1023 is an allosteric activator of Lyn kinase (EC50 = 63 nM). It has no significant activity against a panel of related kinases. MLR-1023 is orally bioavailable and reduces blood glucose levels in mice subjected to an oral glucose tolerance test. This effect is insulin-dependent, with MLR-1023 increasing insulin receptor sensitivity. MLR-1023 produces a dose-dependent and durable glucose-lowering effect in chronically treated db/db mice without causing weight gain.

Uses

Tolimidone (MLR-1023) is an allosteric Lyn kinase activator that has been shown to reduce blood glucose levels in mice. Studies show that Tolimidone is an effective insulin receptor-potentiating agent that is potentially capable of producing durable blood glucose-lowering activity in diabetics. Tolimidone is a candidate for the treatment of type 2 diabetes.

storage

Store at +4°C

Tolimidone Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Tolimidone Suppliers

Canada 1 China 79 Germany 1 India 2 United Kingdom 2 United States 14 Global 99
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
ChemShuttle, Inc.
Tel
0510-83588313-802 18800520310;
Email
sales@chemshuttle.com
Country
China
ProdList
3002
Advantage
62
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2782
Advantage
58
CEG Chemical Science&Technology Co., Ltd.
Tel
Mobile:13665161512
Fax
+86-510-68873513
Country
China
ProdList
1785
Advantage
58
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2990
Advantage
60
Nanjing Chempioneer Pharmaceutical Co., Ltd.
Tel
18068075658
Fax
-
Email
sales@chempioneer.com
Country
China
ProdList
1811
Advantage
58
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7979
Advantage
55
Pharmacodia (Beijing) Co.,Ltd
Tel
+86-400-851-9921
Fax
+86-10-82826195
Email
sales@pharmacodia.com
Country
China
ProdList
2317
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
More
Less

View Lastest Price from Tolimidone manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Tolimidone 41964-07-2
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2020-04-24
Shaanxi Dideu Medichem Co. Ltd
Product
Tolimidone 41964-07-2
Price
US $1.00-1.00/KG
Min. Order
1KG
Purity
99%+
Supply Ability
100 tons
Release date
2019-12-26
Shaanxi Dideu Medichem Co. Ltd
Product
Tolimidone 41964-07-2
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%+
Supply Ability
100 tons
Release date
2020-01-14

41964-07-2, TolimidoneRelated Search:

Mifepristone Tolimidone 2(1H)-Pyrimidinone, 5-methoxy- (9CI)

  • Tolimidone
  • 5-(m-Tolyloxy)pyrimidin-2(1H)-one
  • CP-26154
  • 2(1H)-Pyrimidinone, 5-(3-methylphenoxy)-
  • 5-(3-methylphenoxy)-1H-pyrimidin-2-one
  • 5-(3-Methylphenoxy)-2(1H)-pyrimidinone
  • NSC 314335
  • MLR 1023
  • CID-39065
  • 100568
  • MLR 1023 - Tolimidone | CP 26154
  • 5-(3-Methylphenoxy)-2(1H)-pyrimidinone, 95+%
  • Tolimidone (MLR-1023)
  • 41964-07-2