4-CHLORO-6-METHYLTHIOPYRIMIDINE

Product Name: 4-CHLORO-6-METHYLTHIOPYRIMIDINE
CAS No.: 89283-48-7
Chemical Name: 4-CHLORO-6-METHYLTHIOPYRIMIDINE
Synonyms: 4-CHLORO-6-METHYLTHIOPYRIMIDINE;4-chloro-6-MethylpyriMidine-1-thiol;Pyrimidine, 4-chloro-6-(methylthio)-;4-Chloro-6-methylsulfanyl-pyrimidine;4-CHLORO-6-METHYLTHIOPYRIMIDINE ISO 9001：2015 REACH
CBNumber: CB61215962
Molecular Formula: C5H5ClN2S
Formula Weight: 160.62
MOL File: 89283-48-7.mol

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4-CHLORO-6-METHYLTHIOPYRIMIDINE Property

Melting point:: 50-51 °C
Boiling point:: 260 ºC
Density: 1.37
Flash point:: 111 ºC
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: solid
pka: -1.50±0.17(Predicted)
Appearance: Light yellow to yellow Solid
InChIKey: BMQSAIGMUNXTKZ-UHFFFAOYSA-N

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Safety

Risk Statements: 43
Safety Statements: 36/37
WGK Germany: 3
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SYX00015
Product name: 4-Chloro-6-methylthiopyrimidine
Purity: Aldrich
Packaging: 1g
Price: $179
Updated: 2025/07/31

TRC

Product number: C381670
Product name: 4-Chloro-6-methylthiopyrimidine
Packaging: 100mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC144175
Product name: 4-Chloro-6-methylthiopyrimidine
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Matrix Scientific

Product number: 069649
Product name: 4-Chloro-6-methylthiopyrimidine
Purity: 95%
Packaging: 1g
Price: $87
Updated: 2021/12/16

AK Scientific

Product number: W9220
Product name: 4-Chloro-6-methylthiopyrimidine
Packaging: 1g
Price: $104
Updated: 2021/12/16

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4-CHLORO-6-METHYLTHIOPYRIMIDINE Chemical Properties,Usage,Production

Synthesis

1193-21-1

5188-07-8

89283-48-7

Example 12: Synthesis of 4-chloro-6-(methylthio)pyrimidine. 4,6-Dichloropyrimidine (15.4 g, 0.10 mol) was dissolved in THF (120 mL) at room temperature, followed by the addition of solid sodium methanethiol (NaSMe, 8.5 g, 0.12 mol). The reaction mixture was heated to 60 °C and maintained for 16 hours. After completion of the reaction, the mixture was cooled to room temperature and diluted with ethyl acetate (300 mL) and water (300 mL). The organic layer was separated, washed with brine, dried over anhydrous sodium sulfate and concentrated to give an orange colored oil. Recrystallization by hexane gave the light yellow solid product 4-chloro-6-(methylthio)pyrimidine (9.85 g, 0.061 mol, 61% yield).1H NMR (500 MHz, CDCl3) δ: 8.74 (s, 1H), 7.23 (s, 1H), 2.58 (s, 3H).

References

[1] Patent: WO2006/52913, 2006, A1. Location in patent: Page/Page column 236-237
[2] Patent: WO2008/77548, 2008, A1. Location in patent: Page/Page column 46
[3] Patent: WO2009/85913, 2009, A1. Location in patent: Page/Page column 64-65
[4] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 23, p. 6529 - 6533
[5] Patent: WO2011/45353, 2011, A1. Location in patent: Page/Page column 42-43

4-CHLORO-6-METHYLTHIOPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLORO-6-METHYLTHIOPYRIMIDINE Suppliers

China 75 Germany 1 India 2 United Kingdom 1 United States 9 Global 88

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Bide Pharmatech Ltd.

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View Lastest Price from 4-CHLORO-6-METHYLTHIOPYRIMIDINE manufacturers

Dideu Industries Group Limited

Product: 4-CHLORO-6-METHYLTHIOPYRIMIDINE 89283-48-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-15

89283-48-7, 4-CHLORO-6-METHYLTHIOPYRIMIDINERelated Search:

2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate CHLOROMETHYL METHYL SULFIDE Epichlorohydrin Chlorantraniliprole Chloroacetic acid Difluorochloromethane 4-CHLORO-6-(METHYLSULFANYL)-2-PHENYL-5-PYRIMIDINECARBONITRILE 4-CHLORO-6-(2-THIENYLSULFANYL)-2-PYRIMIDINAMINE 4-CHLORO-5-CYANO-2-METHYL-6-(METHYLTHIO)PYRIMIDINE 4-CHLORO-6-[(4-FLUOROPHENYL)SULFANYL]-2-PYRIMIDINAMINE 4-CHLORO-6-(PHENYLSULFANYL)-2-PYRIMIDINAMINE 4-CHLORO-6-METHYLTHIOPYRIMIDINE BUTTPARK 16\06-46 4-CHLORO-2-(METHYLTHIO)-6-[(5-PHENYL-4H-1,2,4-TRIAZOL-3-YL)THIO]PYRIMIDINE METHYL 3-[(2-AMINO-6-CHLORO-4-PYRIMIDINYL)SULFANYL]PROPANOATE 4-CHLORO-6-([5-(4-CHLOROPHENYL)-4H-1,2,4-TRIAZOL-3-YL]THIO)-2-(METHYLTHIO)PYRIMIDINE BUTTPARK 16\06-47 4-CHLORO-6-[(4-METHYLPHENYL)SULFANYL]-2-PHENYLPYRIMIDINE

4-CHLORO-6-METHYLTHIOPYRIMIDINE

4-chloro-6-MethylpyriMidine-1-thiol

4-Chloro-6-methylsulfanyl-pyrimidine

Pyrimidine, 4-chloro-6-(methylthio)-

4-CHLORO-6-METHYLTHIOPYRIMIDINE ISO 9001：2015 REACH

89283-48-7

Heterocycle-Pyrimidine series