Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monoh ydrochloride

Product Name: Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monoh ydrochloride
CAS No.: 101526-62-9
Chemical Name: Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monoh ydrochloride
Synonyms: CK-1752;Ck 1752a;Sematilide HCl;Sematilide (CK-1752);Sematilide hydrochloride;Sematilide monohydrochloride;Sematilide monohydrochloride monohydrate;Sematilide monohydrate monohydrochloride;N-[2-(diethylamino)ethyl]-4-(methanesulfonamido)benzamide,hydrochloride;N-(2-(Diethylamino)ethyl)-4-((methylsulfonyl)amino)benzamide monohydrochloride
CBNumber: CB61245219
Molecular Formula: C14H23N3O3SHClH2O
Formula Weight: 0
MOL File: 101526-62-9.mol

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Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monoh ydrochloride Property

Melting point:: 141-142° (Lumma); mp 137° and mp 142° (Argentieri)
storage temp.: 2-8°C
solubility: H2O: ≥16mg/mL
pka: pKa1 7.60; pKa2 9.51(at 25℃)
form: powder
color: white to beige

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Safety

WGK Germany: 3
Toxicity: LD50 i.p. in mice: 250-300 mg/kg (Lumma); LD50 in mice, rats, dogs (mg/kg): 96, 92, 143-175 i.v.; 1,800, 3,200, 500-1,000 orally (Argentieri)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S0323
Product name: Sematilide monohydrochloride monohydrate
Purity: ≥98% (HPLC), powder
Packaging: 50mg
Price: $620
Updated: 2023/01/07

Sigma-Aldrich

Product number: S0323
Product name: Sematilide monohydrochloride monohydrate
Purity: ≥99% (HPLC), white solid
Packaging: 10mg
Price: $136
Updated: 2022/05/15

Cayman Chemical

Product number: 28272
Product name: Sematilide (hydrochloride)
Packaging: 10mg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 28272
Product name: Sematilide (hydrochloride)
Packaging: 50mg
Price: $469
Updated: 2024/03/01

Cayman Chemical

Product number: 28272
Product name: Sematilide (hydrochloride)
Packaging: 5mg
Price: $68
Updated: 2024/03/01

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Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monoh ydrochloride Chemical Properties,Usage,Production

Uses

Cardiac depressant (anti-arrhythmic).

Uses

Sematilide, also known as CK-1752, is a class III antiarrhythmic. It is a selective delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of action potential duration and refractoriness.

Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monoh ydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monoh ydrochloride Suppliers

China 18 Switzerland 1 United Kingdom 1 United States 11 Global 31

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101526-62-9, Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monoh ydrochlorideRelated Search:

Semaglutide N-(DIETHYLAMINOETHYL)-4-METHYLSULFOAMINOBENZAMIDE Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monoh ydrochloride 4-(Methylsulfonylamino)benzylamine 4-(METHYLSULFONYLAMINO)BENZYLAMINEHYDROCHLORIDE

Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monoh ydrochloride

CK-1752A, N-[2-(Diethylamino)ethyl]-4μ-[(methylsulfonyl)amino]benzamide monohydrate monohydrochloride

Sematilide monohydrate monohydrochloride

Ck 1752a

N-(2-(Diethylamino)ethyl)-4-((methylsulfonyl)amino)benzamide monohydrochloride

Sematilide HCl

Sematilide hydrochloride

Sematilide monohydrochloride

N-(2-(Diethylamino)ethyl)-4-((methylsulfonyl)amino)benzamide monohydrochloride monohydrate

Sematilide monohydrochloride monohydrate

CK-1752

Benzamide,N-[2-(diethylamino)ethyl]-4-[(methylsulfonyl)amino]-, hydrochloride (1:1)

Sematilide (CK-1752)

SEMATILIDE HYDROCHLORIDE; SEMATILIDE HCL; SEMATILIDE HYDROCHLORIDE; SEMATILIDE; CK-1752A; CK1752A; CK 1752A; CK-1752; CK1752; CK 1752.

N-[2-(diethylamino)ethyl]-4-(methanesulfonamido)benzamide,hydrochloride

CK 1752,Potassium Channel,antiarrhythmic,channel,blocker,Sematilide,Inhibitor,KcsA,inhibit,current,CK1752,Sematilide hydrochloride,IKr

101526-62-9

C14H23N3O3SHClH2O