MONASCIN

Product Name: MONASCIN
CAS No.: 21516-68-7
Chemical Name: MONASCIN
Synonyms: Moscin;MONASCIN;Ccris 9138;Monascoflavin;MONASCINMONASCIN;Monascin >=97.0% (HPLC);(3S,3aR,9aR)-3-Hexanoyl-9a-methyl-6-((E)-propenyl)-3a,4,8,9a-tetrahydro-3H-furo[3,2-g]isochromene-2,9-dione;(3S)-3aα,4,8,9a-Tetrahydro-9aβ-methyl-3-(1-oxohexyl)-6-[(E)-1-propenyl]-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione;(3S,3aR,9aR)-3-Hexanoyl-9a-methyl-6-((E)-prop-1-en-1-yl)-3a,4,8,9a-tetrahydro-2H-furo[3,2-g]isochromen-2,9(3H)-dione;(3S,3aR,9aR)-3-hexanoyl-9a-methyl-6-((E)-prop-1-en-1-yl)-3a,4,8,9a-tetrahydro-2H-furo[3,2-g]isochromene-2,9(3H)-dione
CBNumber: CB61267981
Molecular Formula: C21H26O5
Formula Weight: 358.43
MOL File: 21516-68-7.mol

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MONASCIN Property

Melting point:: 145 °C
Boiling point:: 574.6±50.0 °C(Predicted)
Density: 1.18±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Acetonitrile: Soluble
Chloroform: Soluble
form: Solid
pka: 10.59±0.60(Predicted)
color: Light yellow to yellow
BRN: 51355
InChI: InChI=1S/C21H26O5/c1-4-6-7-9-17(22)18-16-11-13-10-14(8-5-2)25-12-15(13)19(23)21(16,3)26-20(18)24/h5,8,10,16,18H,4,6-7,9,11-12H2,1-3H3/b8-5+/t16-,18+,21-/m1/s1
InChIKey: XXKNHBAFFJINCK-RVEJDSBJSA-N
SMILES: C1(/C=C/C)OCC2C(=O)[C@]3(C)OC(=O)[C@H](C(=O)CCCCC)[C@@]3([H])CC=2C=1

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Safety

WGK Germany: 2

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 52442
Product name: Monascin
Purity: ≥97.0% (HPLC)
Packaging: 1mg
Price: $414.4
Updated: 2025/07/31

Biorbyt Ltd

Product number: orb594585
Product name: Monascin
Packaging: 5mg
Price: $778.6
Updated: 2021/12/16

ChemScene

Product number: CS-0062869
Product name: Monascin
Purity: 99.79%
Packaging: 5mg
Price: $1000
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb594585
Product name: Monascin
Packaging: 10mg
Price: $1356.6
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: DYE0003576
Product name: MONASCIN
Purity: 95.00%
Packaging: 5MG
Price: $4503.69
Updated: 2021/12/16

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MONASCIN Chemical Properties,Usage,Production

Uses

Monascin is an azaphilonoid pigment extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration.

Definition

ChEBI: An organic heterotricyclic compound that is 3a,4,8,9a-tetrahydro-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione that is substituted at positions 3, 6, and 9a by hexanoyl, (1E)-prop-1-en-1-yl an methyl groups, respectively (the 3S,3aR,9aR diastereoisomer). One of the azaphilonoid pigments in extracts of Monascus pilosus-fermented rice (red-mould rice), it is a potent inhibitor of car inogenesis measured against chemical- or UV-initiated, phorbol-promoted mouse skin tumours.

Biochem/physiol Actions

Monascin is one of the azaphilonoid pigments in extracts of Monascus pilosus-fermented rice (red-mold rice). It is a potent inhibitor of carcinogenesis measured against chemical or UV initiated, phorbol-promoted mouse skin tumors.

References

[1] WEI-HSUAN HSU . Monascin and ankaflavin act as natural AMPK activators with PPARα agonist activity to down-regulate nonalcoholic steatohepatitis in high-fat diet-fed C57BL/6 mice[J]. Food and Chemical Toxicology, 2014, 64: Pages 94-103. DOI: 10.1016/j.fct.2013.11.015
[2] TOSHIHIRO AKIHISA. Anti-Tumor-Initiating Effects of Monascin, an Azaphilonoid Pigment from the Extract of Monascus pilosus Fermented Rice (Red-Mold Rice)[J]. Chemistry & Biodiversity, 2005, 2 10: 1305-1309. DOI: 10.1002/cbdv.200590101
[3] YEU-CHING SHI Tzu M P Vivian Hsiu Chuan Liao. Monascin from red mold dioscorea as a novel antidiabetic and antioxidative stress agent in rats and Caenorhabditis elegans[J]. Free Radical Biology and Medicine, 2012, 52 1: Pages 109-117. DOI: 10.1016/j.freeradbiomed.2011.09.034

MONASCIN Preparation Products And Raw materials

Raw materials

Preparation Products

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MONASCIN Suppliers

China 70 India 1 Switzerland 1 United Kingdom 1 United States 6 Global 79

Chengdu Greenpure Biopharma CO.,Ltd

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Chengdu Biopurify Phytochemicals Ltd.

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ShangHai YuanYe Biotechnology Co., Ltd.

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Sigma-Aldrich

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Watson Biotechnology Co.,Ltd

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Alta Scientific Co., Ltd.

Tel: 022-6537-8550 15522853686
Fax: 022-2532-9655
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Wuhan ChemFaces Biochemical Co., Ltd.

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21516-68-7, MONASCINRelated Search:

TURMERIC 1G [R] Muscone Xanthiazone 4-Methoxybenzoic acid 2-(4-hydroxyphenyl)ethyl ester menisdaurin ALPHA-CARYOPHYLLENE Hydroxycitric acid GLUCOTROPAEOLIN ANKAFLAVIN Z-LIGUSTILIDE Camphene Xanthiside 2-Acetylbutyrolactone CIS-3-HEXENYL CAPRYLATE MONASCIN 5-ACETYLTETRAHYDROFURAN-2-ONE (+)-P-MENTH-1-EN-9-OL ACETIC ACID 2-OXO-CYCLOHEX-3-ENYL ESTER

MONASCIN

(3S)-3aα,4,8,9a-Tetrahydro-9aβ-methyl-3-(1-oxohexyl)-6-[(E)-1-propenyl]-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione

Monascoflavin

Ccris 9138

(3S,3aR,9aR)-3a,4,8,9a-Tetrahydro-9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propenyl-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione

(3S,3aR,9aR)-3-Hexanoyl-9a-methyl-6-((E)-propenyl)-3a,4,8,9a-tetrahydro-3H-furo[3,2-g]isochromene-2,9-dione

2H-Furo[3,2-g][2]benzopyran-2,9(3H)-dione, 3a,4,8,9a-tetrahydro-9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propen-1-yl-, (3S,3aR,9aR)-

Monascin >=97.0% (HPLC)

MONASCINMONASCIN

(3S,3aR,9aR)-3-hexanoyl-9a-methyl-6-((E)-prop-1-en-1-yl)-3a,4,8,9a-tetrahydro-2H-furo[3,2-g]isochromene-2,9(3H)-dione

Moscin

(3S,3aR,9aR)-3-Hexanoyl-9a-methyl-6-((E)-prop-1-en-1-yl)-3a,4,8,9a-tetrahydro-2H-furo[3,2-g]isochromen-2,9(3H)-dione

21516-68-7