PG 501
- Product Name
- PG 501
- CAS No.
- 32891-29-5
- Chemical Name
- PG 501
- Synonyms
- PG 501;Pentona;KAO 264;mazaticol hydrochloride;9-Azabicyclo[3.3.1]nonane, 2-thiopheneacetic acid deriv.;6,6,9-Trimethyl-9-azabicyclo[3.3.1]non-3b-yl a,a-di(2-thienyl)glycolate hydrochloride;6,6,9-Trimethyl-9-azabicyclo[3.3.1]nonan-3b-ol a,a-di-2-thienylglycolate (ester) hydrochloride;Glycolic acid, di-2-thienyl-, 6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester hydrochloride, exo- (8CI);2-Thiopheneacetic acid, a-hydroxy-a-2-thienyl-, 6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester, hydrochloride, exo-;2-Thiopheneacetic acid, a-hydroxy-a-2-thienyl-, (1R,3R,5R)-6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester, hydrochloride, rel- (9CI)
- CBNumber
- CB61269985
- Molecular Formula
- C21H27NO3S2.HCl
- Formula Weight
- 0
- MOL File
- 32891-29-5.mol
N-Bromosuccinimide Price
- Product number
- API0003264
- Product name
- PG 501
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.87
- Updated
- 2021/12/16
PG 501 Chemical Properties,Usage,Production
Originator
Pentona, Tanabe ,Japan ,1978
Definition
ChEBI: Mazaticol hydrochloride is an organic molecular entity.
Manufacturing Process
A mixture of 1.0 g of 6,6,9-trimethyl-9-azabicyclo[3.3.1]nonan-3β-ol, methyl α,α-di-(2-thienyl)-glycolate and 30 mg of metallic sodium is heated at 80°C to 90°C for about 2 hours under reduced pressure. After cooling, ether is added to the reaction mixture. The mixture is extracted with 10% hydrochloric acid. The aqueous layer is alkalified with sodium carbonate and reextracted with ethyl acetate. The extract is washed with water, dried and concentrated to dryness. The residue thus obtained is treated with hydrogen chloride by conventional manner. 2.0 g of the α,α-di-(2-thienyl)glycolate of 6,6,9- trimethyl-9-azabicyclo[3.3.1]nonan-3β-ol hydrochloride are obtained. Yield 83%.
Therapeutic Function
Antiparkinsonian
PG 501 Preparation Products And Raw materials
Raw materials
Preparation Products
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