ChemicalBook > CAS DataBase List > 2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID

2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID

Product Name
2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID
CAS No.
4746-63-8
Chemical Name
2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID
Synonyms
Aclidinium Impurity 3;Dithienylglycolic acid;Di-2-thienylglycolic Acid;Titropium bromide EP impurity A;Tiotropium Bromide EP Impurity A;2-HYDROXY-2,2-DITHIOPHEN-2-YLACETICACID;2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID;2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-;Tiotropium Bromide EP Impurity B (Aclidinium Impurity 3);Tiotropium Bromide Impurity 1(Tiotropium Bromide EP Impurity A)
CBNumber
CB3749100
Molecular Formula
C10H8O3S2
Formula Weight
240.29
MOL File
4746-63-8.mol
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2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID Property

Melting point:
93 °C
Boiling point:
436.5±40.0 °C(Predicted)
Density 
1.527±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Sparingly), Methanol (Slightly, Sonicated)
form 
Solid
pka
2.79±0.25(Predicted)
color 
Light Grey to Black
Stability:
Light Sensitive
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D493915
Product name
Di-2-thienylglycolicAcid
Packaging
250mg
Price
$185
Updated
2021/12/16
Biosynth Carbosynth
Product number
IH41893
Product name
2-Hydroxy-2,2-bis(2-thienyl) acetic acid
Packaging
5G
Price
$300
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
106176
Product name
2-Hydroxy-2-2-bis(2-thienyl)aceticacid
Packaging
25mg
Price
$350
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0149604
Product name
2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID
Purity
95.00%
Packaging
5MG
Price
$497.86
Updated
2021/12/16
Biosynth Carbosynth
Product number
IH41893
Product name
2-Hydroxy-2,2-bis(2-thienyl) acetic acid
Packaging
10g
Price
$500
Updated
2021/12/16
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2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID Chemical Properties,Usage,Production

Uses

Di-2-thienylglycolic Acid is an analog of Methyl Di(2-thienylglycolate) (M303765), an intermediate in the production of Tiotropium Bromide (T444850), a long-acting bronchodilator.

2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID Suppliers

China 64 India 4 United Kingdom 3 United States 6 Global 77
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4746-63-8, 2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACIDRelated Search:

2-HYDROXY-2,2-BIS(2-THIENYL)ACETIC ACID METHYL ESTER Scopine-2,2-dithienyl glycolate Tiotropium bromide (2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid BIS(2-THIENYL) KETONE Salbutamol LCZ 696 Impurity C LCZ 696 Impurity B rac-Lipoic Acid Impurity 1 (S-Oxide) 3-(3-fluorobenzyl)-4-(3-fluoro-benzyloxy)benzaldehyde 4-Benzyl Albuterol [R(R*,R*]-2-amino-1-[p-(methylsulphonyl)phenyl]propane-1,3-diol Tiotropium bromide Impurity 16 (1α,2β,4β,5α)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7α-ol 2,3-Dibromothiophene Teloidine Ethanedioic acid,1-methyl ester, potassium salt (1:1) TiotropiuM BroMide IMpurity I

  • 2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID
  • Di-2-thienylglycolic Acid
  • 2-HYDROXY-2,2-DITHIOPHEN-2-YLACETICACID
  • Aclidinium Impurity 3
  • Tiotropium Bromide Impurity 1(Tiotropium Bromide EP Impurity A)
  • Tiotropium Bromide EP Impurity A
  • 2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-
  • Tiotropium Bromide EP Impurity B (Aclidinium Impurity 3)
  • Dithienylglycolic acid
  • Titropium bromide EP impurity A
  • 4746-63-8
  • C10H8O3S2
  • Sulphur Derivatives
  • Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals