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marinobufagenin

Product Name
marinobufagenin
CAS No.
470-42-8
Chemical Name
marinobufagenin
Synonyms
Marinobufagin;Marinobufogenin;marinobufagenin;Marinobufagin(Marinobufagenin);3β,5β-Dihydroxy-14β,15β-epoxybufa-20,22-dienolide;3β,5-Dihydroxy-14,15β-epoxy-5β-bufa-20,22-dienolide;14,15β-Epoxy-3β,5-dihydroxy-5β-bufa-20,22-dienolide;(3β,5β,15β)-3,5-Dihydroxy-14,15-epoxybufa-20,22-dienolide;Bufa-20,22-dienolide, 14,15-epoxy-3,5-dihydroxy-, (3β,5β,15β)-;5-((1R,2aR,3aS,3bR,5aS,7S,9aR,9bS,11aR)-5a,7-dihydroxy-9a,11a-dimethylhexadecahydronaphtho[1',2':6,7]indeno[1,7a-b]oxiren-1-yl)-2H-pyran-2-one
CBNumber
CB61360037
Molecular Formula
C24H32O5
Formula Weight
400.52
MOL File
470-42-8.mol
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marinobufagenin Property

Melting point:
224-225 °C
Boiling point:
589.0±50.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 3 mg/ml; DMF:PBS (pH 7.2) (1:8): 0.1 mg/ml; Ethanol: 1 mg/ml
form 
A crystalline solid
pka
14.77±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20798
Product name
Marinobufagenin
Purity
≥98%
Packaging
500μg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
20798
Product name
Marinobufagenin
Purity
≥98%
Packaging
1mg
Price
$107
Updated
2024/03/01
Cayman Chemical
Product number
20798
Product name
Marinobufagenin
Purity
≥98%
Packaging
5mg
Price
$467
Updated
2024/03/01
Biosynth Carbosynth
Product number
FM167440
Product name
Marinobufagenin
Packaging
5mg
Price
$550
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
73875
Product name
Marinobufagin
Purity
98%
Packaging
5mg
Price
$590
Updated
2021/12/16
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marinobufagenin Chemical Properties,Usage,Production

Uses

Marinobufagin is a bufadienolide with anti-gastric cancer effect. A bioactive steroid that also functions as an endogenous Na/K-ATPase bufadienolide inhibitor that plays a major role in human cardiovascular diseases.

Definition

ChEBI: Marinobufagenin is a cardiotonic steroid secreted by the toad Bufo rubescens and other related species such as Bufo marinus. An endogenous Na/K-ATPase inhibitor, it is a vasoconstrictor with effects similar to digitalis. It has a role as an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor and an epitope. It is a steroid hormone and an epoxy steroid. It is functionally related to a (5beta)-bufadienolide.

marinobufagenin Preparation Products And Raw materials

Raw materials

Preparation Products

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470-42-8, marinobufageninRelated Search:


  • marinobufagenin
  • 14,15β-Epoxy-3β,5-dihydroxy-5β-bufa-20,22-dienolide
  • 3β,5-Dihydroxy-14,15β-epoxy-5β-bufa-20,22-dienolide
  • 3β,5β-Dihydroxy-14β,15β-epoxybufa-20,22-dienolide
  • Marinobufagin
  • Marinobufogenin
  • (3β,5β,15β)-3,5-Dihydroxy-14,15-epoxybufa-20,22-dienolide
  • Bufa-20,22-dienolide, 14,15-epoxy-3,5-dihydroxy-, (3β,5β,15β)-
  • Marinobufagin(Marinobufagenin)
  • 5-((1R,2aR,3aS,3bR,5aS,7S,9aR,9bS,11aR)-5a,7-dihydroxy-9a,11a-dimethylhexadecahydronaphtho[1',2':6,7]indeno[1,7a-b]oxiren-1-yl)-2H-pyran-2-one
  • 470-42-8
  • Vasoconstrictor Agents
  • Enzyme Inhibitors