PKSI 527

Product Name
PKSI 527
CAS No.
128837-71-8
Chemical Name
PKSI 527
Synonyms
PKSI 527,PKSI527;2-[4-[[(2S)-2-[[4-(aminomethyl)cyclohexanecarbonyl]amino]-3-phenylpropanoyl]amino]phenyl]aceticacid,hydrochloride;2-(4-((S)-2-(trans-4-(Aminomethyl)cyclohexane-1-carboxamido)-3-phenylpropanamido)phenyl)acetic acid hydrochloride;Benzeneacetic acid, 4-[[(2S)-2-[[[trans-4-(aminomethyl)cyclohexyl]carbonyl]amino]-1-oxo-3-phenylpropyl]amino]-, hydrochloride (1:1)
CBNumber
CB61393901
Molecular Formula
C25H31N3O4.ClH
Formula Weight
473.998
MOL File
128837-71-8.mol
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PKSI 527 Property

storage temp. 
-20°C
solubility 
Soluble in Water (5 mg/ml)
form 
White solid.
color 
White
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in water may be stored at -20°C for up to 3 months.
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23974
Product name
PKSI-527
Purity
≥95%
Packaging
5mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
23974
Product name
PKSI-527
Purity
≥95%
Packaging
25mg
Price
$505
Updated
2024/03/01
AK Scientific
Product number
6192CJ
Product name
2-[4-[[(2S)-2-[[4-(Aminomethyl)cyclohexanecarbonyl]amino]-3-phenylpropanoyl]amino]phenyl]aceticacid;hydrochloride
Packaging
5mg
Price
$233
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000084
Product name
PKSI-527
Purity
95.00%
Packaging
5MG
Price
$503.38
Updated
2021/12/16
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PKSI 527 Chemical Properties,Usage,Production

Description

PKSI-527 (128837-71-8) is a selective plasma kallikrein inhibitor (Ki = 0.81 μM)1 that can be used for affinity purification of kallikrein2.? Synergizes with NO donors to produce antithrombic effects ex-vivo.3? Suppresses collagen-induced arthritis in mouse models.4

References

Wanaka et al. (1992), Synthesis of trans-4-aminomethylcyclohexanecarbonyl-L- and –D-phenylalanine-4-carboxymethylanilide and examination of their inhibitory activity against plasma kallikrein;? ?Chem. Pharm. Bull., 40 1814 Tada et al. (2001), Isolation of plasma kallikrein by high efficiency affinity chromatography and its characterization; Chem. Pharm. Bull., 24 520 Ikarugi et al. (2005), Synergistic antithrombotic effect of a combination of NO donor and plasma kallikrein inhibitor; Thromb. Res., 116 403 Fujimori et al. (1993), Effects of a highly selective plasma kallikrein inhibitor on collagen-induced arthritis in mice; Agents Actions, 39 42

PKSI 527 Preparation Products And Raw materials

Raw materials

Preparation Products

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PKSI 527 Suppliers

China 6 South Korea 1 United States 4 Global 11
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
62075
Advantage
58
Shanghai Jieshikai Biotechnology Co. , Ltd.
Tel
021-57520305 15221441005
Email
wangkang@jskchem.com
Country
China
ProdList
49234
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
19704
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58

128837-71-8, PKSI 527Related Search:

1-[4-[(2,3,3-Trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid Nitrendipine Cilostazol IWP-2 CHEMBRDG-BB 9070456 PKSI 527 1,4-Cyclohexanebis(methylamine) Actarit

  • 2-[4-[[(2S)-2-[[4-(aminomethyl)cyclohexanecarbonyl]amino]-3-phenylpropanoyl]amino]phenyl]aceticacid,hydrochloride
  • PKSI 527,PKSI527
  • 2-(4-((S)-2-(trans-4-(Aminomethyl)cyclohexane-1-carboxamido)-3-phenylpropanamido)phenyl)acetic acid hydrochloride
  • Benzeneacetic acid, 4-[[(2S)-2-[[[trans-4-(aminomethyl)cyclohexyl]carbonyl]amino]-1-oxo-3-phenylpropyl]amino]-, hydrochloride (1:1)
  • 128837-71-8