Trimethylamine N-oxide

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Trimethylamine N-oxide

Product Name: Trimethylamine N-oxide
CAS No.: 1184-78-7
Chemical Name: Trimethylamine N-oxide
Synonyms: TMAO;Trimethylamine oxide;N,N-dimethylmethanamine oxide;trimethyloxamine;Trimetlylamine Oxide;Triox;TMANO Anhydrous;TRIMETHYLAMINOXIDE;rimethylamineN-oxide;TRIMETHYLAMINE N-OXIDE
CBNumber: CB6140124
Molecular Formula: C3H9NO
Formula Weight: 75.11
MOL File: 1184-78-7.mol

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Trimethylamine N-oxide Property

Melting point:: 220-222 °C (lit.)
Boiling point:: 133.8°C (rough estimate)
Density: 0.9301 (rough estimate)
vapor pressure: 23.5Pa at 20℃
refractive index: 1.4698 (estimate)
FEMA: 4245 | TRIMETHYLAMINE OXIDE
storage temp.: Hygroscopic, Room Temperature, under inert atmosphere
solubility: Chloroform, DMSO, Methanol (Slightly)
pka: 4.65(at 25℃)
form: Solid
color: Pale Yellow
Odor: odorless
Water Solubility: 793g/L at 24.5℃
Merck: 14,9711
JECFA Number: 1614
Stability:: Hygroscopic
LogP: -2.79
EPA Substance Registry System: Methanamine, N,N-dimethyl-, N-oxide (1184-78-7)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
WGK Germany: 3
HS Code: 2904.20.5000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 317594
Product name: Trimethylamine N-oxide
Purity: 95%
Packaging: 1g
Price: $76.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: 317594
Product name: Trimethylamine N-oxide
Purity: 95%
Packaging: 5g
Price: $163
Updated: 2024/03/01

TCI Chemical

Product number: T1362
Product name: Trimethylamine N-Oxide Anhydrous
Purity: >95.0%(T)
Packaging: 1g
Price: $43
Updated: 2024/03/01

TCI Chemical

Product number: T1362
Product name: Trimethylamine N-Oxide Anhydrous
Purity: >95.0%(T)
Packaging: 5g
Price: $143
Updated: 2024/03/01

Cayman Chemical

Product number: 17354
Product name: Trimethylamine N-oxide
Purity: ≥95%
Packaging: 500mg
Price: $32
Updated: 2024/03/01

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Trimethylamine N-oxide Chemical Properties,Usage,Production

Description

Trimethylamine N-oxide (TMAO) is a metabolite of choline, phosphatidylcholine, and L-carnitine . It is formed by gut microbiota-mediated metabolism of choline, phosphatidylcholine, and L-carnitine to TMA followed by oxidation of TMA by flavin-containing monooxygenase 3 (FMO3) in the liver. Dietary administration of TMAO (0.12% w/w) increases renal tubulointerstitial fibrosis, collagen deposition, and Smad3 phosphorylation in mice and increases aortic lesion area in atherosclerosis-prone ApoE^-/- mice. Plasma levels of TMAO are elevated in patients with chronic kidney disease and decreased in patients with active, compared with inactive, ulcerative colitis. Elevated plasma levels of TMAO are associated with increased risk of cardiovascular disease.

Chemical Properties

White crystalline powder

Chemical Properties

Colorless to yellow solid; odorless.

Uses

Trimethylamine?N-oxide can be used:

As a demetallation?and decarbonylation?reagent for organometallic compounds.
To prepare azomethine ylide by reaction with lithium di-isopropylamide. This, in turn, may be reacted with simple alkenes to obtain corresponding pyrrolidines.
To mediate the conversion of thiols to disulfides.

Definition

ChEBI: An N-oxide derived from triethylamine.

General Description

Trimethylamine?N-oxide is an organic compound that belongs to the class of amine oxides. It is generally found in the tissues of marine organisms, wherein it helps protect them from harsh conditions like salinity, hydrostatic pressure, temperature, and high urea.

Flammability and Explosibility

Not classified

Trimethylamine N-oxide Preparation Products And Raw materials

Raw materials

Hydrogen peroxide Toluene Trimethylamine

Preparation Products

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View Lastest Price from Trimethylamine N-oxide manufacturers

Hebei Kingfiner Technology Development Co.Ltd

Product: Trimethylamine N-oxide 1184-78-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500000kg
Release date: 2023-12-26

Career Henan Chemical Co

Product: TRIMETHYLAMINE N-OXIDE HYDROCHLORIDE 1184-78-7
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-07-04

1184-78-7, Trimethylamine N-oxideRelated Search:

TRIMETHYLAMINE OXIDE DIHYDRATE Ammothamnine CLOZAPINE N-OXIDE Trimethylamine N-oxide N,N-DIMETHYLOCTYLAMINE-N-OXIDE 4-Methylmorpholine N-oxide LDAO DDAO 4-Methylmorpholine N-oxide monohydrate SCOPOLAMINE N-OXIDE HYDROBROMIDE DIMETHYLSTEARYLAMINE OXIDE MYRISTYL DIMETHYLAMINE OXIDE Trimethylamine isatidine ATROPINE N-OXIDE HYDROCHLORIDE 2,2'-(BENZYLIMINO)-DIETHANOL N-OXIDE TRIETHYLAMINE N-OXIDE CODEINE N-OXIDE

n,n-dimethyl-methanaminn-oxide

TMAO

Trimethylamine oxide

trimethyloxamine

Triox

TRIMETHYLAMINE N-OXIDE

TRIMETHYLAMINE OXIDE HYDROCHLORIDE

TRIMETHYLAMINE N-OXIDE HYDROCHLORIDE

trimethyl-oxido-ammonium

TRIMETHYLAMINOXIDE

Trimethylamine N-Oxide Anhydrous

Trimethylamine N-oxide,98%

Trimethylamine N-oxide,TMANO

TriMethylaMine N-oxide 98%

Trimethylamine <i>N</i>-Oxide Anhydrous

Trimetlylamine Oxide

N,N-Dimethylmethanamine N-oxide

Methanamine,N,N-dimethyl-,N-oxide

N,N-dimethylmethanamine oxide

TMANO Anhydrous

rimethylamineN-oxide

Trimethylamine N-oxide ISO 9001：2015 REACH

Trimethylamine Oxide (TMAO)

trimethylamine N-oxide(1184-78-7)

1184-78-7

Others

Synthetic Reagents

Oxidation

Synthetic Organic Chemistry