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4-Methylmorpholine N-oxide

Product Name
4-Methylmorpholine N-oxide
CAS No.
7529-22-8
Chemical Name
4-Methylmorpholine N-oxide
Synonyms
NMO;4-METHYLMORPHOLINE 4-OXIDE;N-Methylmorpholine oxide;Morpholine, 4-methyl-, 4-oxide;4-methyl-morpholin4-oxide;MMNO;NSC 73198;NSC 82153;ine N-oxide;nmo solution
CBNumber
CB7305470
Molecular Formula
C5H11NO2
Formula Weight
117.15
MOL File
7529-22-8.mol
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4-Methylmorpholine N-oxide Property

Melting point:
180-184 °C(lit.)
Boiling point:
118-119°C
Density 
1,14 g/cm3
vapor pressure 
1.41hPa at 20℃
refractive index 
n20/D 1.43
Flash point:
118-119°C
storage temp. 
2-8°C
solubility 
DMSO (Soluble), Methanol (Slightly)
form 
Liquid
pka
4.93±0.20(Predicted)
color 
Clear colorless to yellow
PH
9.00 ( in neat)
Water Solubility 
Soluble in water, methanol, ethanol, acetone, ethers and dimethylsulfoxide.
BRN 
507437
Stability:
Hygroscopic
LogP
-1.2 at 25℃
CAS DataBase Reference
7529-22-8(CAS DataBase Reference)
NIST Chemistry Reference
N-Methylmorpholine-N-oxide(7529-22-8)
EPA Substance Registry System
Morpholine, 4-methyl-, 4-oxide (7529-22-8)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37
WGK Germany 
1
TSCA 
Yes
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H228Flammable solid

H272May intensify fire; oxidizer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P220Keep/Store away from clothing/…/combustible materials.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.14779
Product name
4-Methylmorpholine 4-oxide
Purity
(50% solution in water) for synthesis
Packaging
250ML
Price
$53.7
Updated
2024/03/01
Sigma-Aldrich
Product number
8.14779
Product name
4-Methylmorpholine 4-oxide
Purity
(50% solution in water) for synthesis
Packaging
1L
Price
$168
Updated
2024/03/01
Sigma-Aldrich
Product number
224286
Product name
4-Methylmorpholine N-oxide
Purity
97%
Packaging
5g
Price
$55.3
Updated
2024/03/01
Sigma-Aldrich
Product number
224286
Product name
4-Methylmorpholine N-oxide
Purity
97%
Packaging
25g
Price
$149
Updated
2024/03/01
TCI Chemical
Product number
M0981
Product name
4-Methylmorpholine N-Oxide (50% in Water, ca. 4.8mol/L)
Packaging
25mL
Price
$18
Updated
2024/03/01
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4-Methylmorpholine N-oxide Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to yellow solution

Uses

4-Methylmorpholine N-Oxide is a metabolite of Morpholine (M723725). N-Methylmorpholine N-Oxide is commonly used to dissolve cellulose as well as in the dissolution of of scleroproteins.

Uses

4-Methylmorpholine N-oxide acts as a non-metallic catalyst for the cyanosilylation of ketones. It is also employed as a co-oxidant for Sharpless asymmetric dihydroxylation in ionic liquids. It serves as a solvent in the Lyocell process to produce tencel fiber. Further, it is used in the preparation of aldehydes from primary alcohols in the presence of tetrapropylammonium perruthenate.

Uses

Non-metallic catalyst for the cyanosilylation of ketones. Co-oxidant for Sharpless asymmetric dihydroxylation in ionic liquids.

Definition

ChEBI: N-methylmorpholine N-oxide is a morpholine N-oxide resulting from the oxidation of the amino group of N-methylmorpholine.

General Description

4-Methylmorpholine?N-oxide is an organic compound used as a co-oxidant along with OsO4 and ruthenates in organic synthesis. In recent studies, it has been used as a catalyst in silylcyanation of aldehydes and ketones. Lyocell, a regenerated cellulose fiber, can be prepared using 4-methylmorpholine?N-oxide in an eco-friendly manner.

Flammability and Explosibility

Flammable

Purification Methods

When the oxide is dried for 2-3hours at high vacuum, it dehydrates. Add MeOH to the oxide and distil off the solvent under vacuum until the temperature is ca 95o. Then add Me2CO at reflux and cool to 20o. The crystals are filtered off, washed with Me2CO and dried. The degree of hydration may vary and may be important for the desired reactions. [van Rheenan et al. Tetrahedron Lett 1973 1076, Schneider & Hanze US Pat 2 769 823; see also Sharpless et al. Tetrahedron Lett 2503 1976.]

4-Methylmorpholine N-oxide Preparation Products And Raw materials

Raw materials

Preparation Products

4-METHYL-2-OXO-2 H-CHROMENE-7-CARBALDEHYDE 4-Methylmorpholine N-oxide monohydrate
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4-Methylmorpholine N-oxide Suppliers

Americas 1 Belgium 1 Canada 2 China 339 Europe 4 Germany 8 India 31 Japan 4 South Korea 1 Switzerland 1 United Kingdom 15 United States 33 Global 440
Jiangsu lianrun chemical co. LTD
Tel
0517-85322222 17625179812
Email
sales@lianrunchem.com
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China
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Jiaxing Deyi Chemical Co., Ltd.
Tel
86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
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China
ProdList
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Shanghai TongYuan Chemical Co., Ltd.
Tel
021-021-69182866 13701855675
Fax
021-69182022
Email
tongyuanchem@126.com
Country
China
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Shanghai Witofly Chemical Co. ,Ltd.
Tel
021-021-50630626 18964684208
Email
sales@witofly.com
Country
China
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Nanjing XiLang Chemical Products Co., Ltd.
Tel
025-5276156 18936048580
Email
chemxilang@163.com
Country
China
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Shanghai demo pharmaceutical technology co., LTD
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400-0217337 13341686687
Fax
021-50182339
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2355568894@qq.com
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China
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Ningbo Hua Tuo Chemical Co., Ltd.
Tel
+86-0574-88237971 +86-15267895909
Fax
0574-88237323
Email
mia@sinotopchem.com
Country
China
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Nanjing Taihehua Electronics Co., Ltd
Tel
18852048848
Email
943629434@qq.com
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China
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Tianjinshi Haydn Science &Technology Development Co.,Ltd
Tel
022-88294560 13642153692
Email
313878807@qq.com
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China
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Wuhan EnTai Technology Development Co,.Ltd
Tel
86-27-82330560
Fax
86-27-82330547
Email
2536851935@qq.com
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China
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View Lastest Price from 4-Methylmorpholine N-oxide manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
4-Methylmorpholine N-oxide 7529-22-8
Price
US $20.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
200000kg
Release date
2024-04-26
Henan Fengda Chemical Co., Ltd
Product
4-Methylmorpholine N-oxide 7529-22-8
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09
Hebei Kingfiner Technology Development Co.Ltd
Product
4-Methylmorpholine N-oxide 7529-22-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000kg
Release date
2024-03-27

7529-22-8, 4-Methylmorpholine N-oxideRelated Search:

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  • 4-Methylmorpholine N-oxide, 50% w/w aq. soln.
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