ChemicalBook > CAS DataBase List > L-KYNURENINE

L-KYNURENINE

Product Name
L-KYNURENINE
CAS No.
2922-83-0
Chemical Name
L-KYNURENINE
Synonyms
CCRIS 4425;L-KYNURENINE;JACS-2922-83-0;(S)-Kynurenine;Kynurenine (L);L-Kynurenine L-Kynurenine Hydrate;L-kynurenine free base;L-KynurenineHydrate>L-KYNURENINE USP/EP/BP
CBNumber
CB6142966
Molecular Formula
C10H12N2O3
Formula Weight
208.21
MOL File
2922-83-0.mol
More
Less

L-KYNURENINE Property

Melting point:
219 °C
Boiling point:
466.6±45.0 °C(Predicted)
Density 
1.343±0.06 g/cm3(Predicted)
refractive index 
-33 ° (C=0.4, H2O)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Soluble in DMSO (up to 2 mg/ml) or in Water (up to 2 mg/ml).
pka
2.21±0.23(Predicted)
form 
crystalline
color 
light yellow
optical activity
-30.525 (H2O)
Merck 
14,5328
Stability:
Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
InChIKey
YGPSJZOEDVAXAB-QMMMGPOBSA-N
CAS DataBase Reference
2922-83-0(CAS DataBase Reference)
More
Less

Safety

WGK Germany 
3
RTECS 
CY9049700
HS Code 
2922500090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
K8625
Product name
L-Kynurenine
Purity
≥98% (HPLC)
Packaging
25mg
Price
$72.7
Updated
2024/03/01
Sigma-Aldrich
Product number
K8625
Product name
L-Kynurenine
Purity
≥98% (HPLC)
Packaging
1g
Price
$518
Updated
2024/03/01
TCI Chemical
Product number
K0016
Product name
L-Kynurenine Hydrate
Purity
>98.0%(T)
Packaging
100mg
Price
$127
Updated
2024/03/01
Alfa Aesar
Product number
J60199
Product name
L-Kynurenine
Packaging
50mg
Price
$79.7
Updated
2024/03/01
Cayman Chemical
Product number
11305
Product name
Kynurenine
Purity
≥98%
Packaging
50mg
Price
$37
Updated
2024/03/01
More
Less

L-KYNURENINE Chemical Properties,Usage,Production

Description

Kynurenine (2922-83-0) is a tryptophan catabolite.1?Endogenous tumor-promoting ligand of the human aryl hydrocarbon receptor (AhR). Constitutively generated by human tumor cells via the action of the tryptophan degrading enzyme, tryptophan-2,3-dioxygenase (TDO). Kynurenine suppresses antitumor immune responses and promotes tumor cell survival and motility.2

Uses

L-Kynurenine has been used as a standard for indoleamine-2,3-dioxygenase (IDO) assay. It has also been used as a standard to extract and quantify kynurenine from cultured cells and media.

Definition

ChEBI: A kynurenine that has L configuration.

Biochem/physiol Actions

Key intermediate in the breakdown pathway of tryptophan.

storage

Store at RT

References

References/Citations 1) Ibana?et al. (2011),?Inhibition of indoleamine 2,3-dioxygenase activity by levo-1-methyl tryptophan blocks gamma interferon-induced Chlaydia trachomatis persistence in human epithelial cells; Infect. Immun.,?79?4425 2) Opitz?et al. (2011),?An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor; Nature,?478?197

L-KYNURENINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

L-KYNURENINE Suppliers

Americas 1 China 172 Europe 1 France 2 Germany 4 India 5 Japan 1 Switzerland 4 United Kingdom 6 United States 29 Global 225
Nanjing Derno Pharmaceutical Technology Co., Ltd.
Tel
025-86957866 13952093866
Fax
025-68661287
Email
sales@dernopharm.com
Country
China
ProdList
924
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4727
Advantage
58
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5047
Advantage
50
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8065
Advantage
58
Nanjing Redwood Fine Chemical Co., Ltd.
Tel
13851620508 13851620508
Fax
86-025-58905816
Email
shirly@redwood.com.cn
Country
China
ProdList
218
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18070
Advantage
56
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
Country
China
ProdList
4511
Advantage
55
Shanghai Synchem Pharma Co., ltd
Tel
21-619849051-1 18521059765
Email
synchempharma@aliyun.com
Country
China
ProdList
6464
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29764
Advantage
68
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Guangzhou Jhd Chemical Reagent Co., Ltd.
Tel
020-84383047
Fax
020-84380294
Email
sales@jhd.com.cn
Country
China
ProdList
9186
Advantage
65
Shenzhen SUNGENING Bio-Medical Co., Ltd.
Tel
0755-28967200 13631290199
Fax
0755-28967200
Email
wxf@sungening.com
Country
China
ProdList
9578
Advantage
60
JinJin Le Chemical Co., Ltd
Tel
10106090
Email
jjlchem2@163.com
Country
China
ProdList
9981
Advantage
58
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
10007
Advantage
58
Shanghai BaiShun Biological Technology Co., Ltd
Tel
021-37581181
Fax
021-57456066
Email
sales@chem-mall.com
Country
China
ProdList
10330
Advantage
58
Aikon International Limited
Tel
025-66028182 18112977050
Fax
(3)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
15818
Advantage
58
Shanghai alkynechem Co., Ltd.
Tel
086-021-15821262312 15821262312
Email
info@alkynechem.com
Country
China
ProdList
1981
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 18016230971
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25004
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6037 18920794737
Email
sales@heowns.com
Country
China
ProdList
23016
Advantage
60
3A Chemicals
Tel
400-668-9898
Fax
010-51582189
Email
service@3achem.com
Country
China
ProdList
20557
Advantage
58
Shanghai neon biological technology co., LTD
Tel
021-54252912-8903
Email
leona.xin@forneeds.cn
Country
China
ProdList
4759
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Beijing OKA biological technology co., LTD
Tel
010-010-010-62971590 18548936886
Fax
010-62340519
Email
jack@oka-vip.com
Country
China
ProdList
6897
Advantage
58
Shanghai silk sail pharmaceutical technology co., LTD
Tel
18916696128
Email
service@snowpharm.com
Country
China
ProdList
1369
Advantage
58
Beijing Minruida Technology Co., Ltd.
Tel
010-82387566 18001021521;
Fax
82387566-801
Email
sales@mreda.com.cn
Country
China
ProdList
10789
Advantage
58
Chengdu MassCale Pharmaceutical Co., Ltd.
Tel
028-84552636 18084815636
Email
chensfsc@126.com
Country
China
ProdList
1445
Advantage
58
More
Less

View Lastest Price from L-KYNURENINE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
L-kynurenine 2922-83-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26
Career Henan Chemical Co
Product
L-KYNURENINE 2922-83-0
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-12-30
Career Henan Chemical Co
Product
L-KYNURENINE 2922-83-0
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-12-30

2922-83-0, L-KYNURENINERelated Search:

3-HYDROXY-L-KYNURENINE 2-(3-INDOLYLMETHYL)-L-TRYPTOPHAN 2-Hydroxy-DL-tryptophan 2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-3-CARBOXYLIC ACID HARMANE-1,2,3,4-TETRAHYDRO-3-CARBOXYLIC ACID Tryptophan EP Impurity L Tryptophan EP Impurity F PEAK E Tryptophan EP Impurity D Tryptophan EP Impurity J N'-formyl-L-Kynurenine Dioxindolyl-L-alanine 5-Hydroxytryptophan 3-(phenylamino)alanine D-1,2,3,4-tetrahydronorharmane-3-carboxylic acid N-formylkynurenine H-PHE-TRP-OH L-Isovaline

  • Tryptophan Impurity 3（Tryptophan EP Impurity C）
  • JACS-2922-83-0
  • L-2-AMINO-3-(2-AMINOBENZOYL)PROPIONIC ACID
  • L-2-AMINO-4-[2-AMINOPHENYL]-4-OXOBUTANOIC ACID
  • L-KYNURENINE
  • L-kynurenine free base
  • β-Anthraniloyl-L-alanine
  • β-Anthraniloyl-L-alanine, L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
  • L-Kynurenine Hydrate
  • (S)-2-Amino-4-oxo-4-(2-aminophenyl)butanoic acid
  • (S)-α,2-Diamino-γ-oxobenzenebutanoic acid
  • 3-(2-Aminobenzoyl)alanine
  • 3-(2-Aminobenzoyl)-L-alanine
  • (2S)-2-amino-4-(2-aminophenyl)-4-keto-butyric acid
  • (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid
  • (2S)-2-azanyl-4-(2-azanylphenyl)-4-oxo-butanoic acid
  • Benzenebutanoic acid, a,2-diaMino-g-oxo-, (aS)-
  • (S)-2-AMino-4-(2-aMinophenyl)-4-oxobutanoic acid
  • L-3-(o-Aminobenzoyl)alanine
  • L-Kynurenine&nbsp
  • <small>L</small>-Kynurenine Hydrate
  • L-KYNURENINE, >=98% (HPLC)
  • Tryptophan EP Impurity C
  • L-KynurenineHydrate&gt
  • (S)-Kynurenine
  • Benzenebutanoic acid, α,2-diamino-γ-oxo-, (αS)-
  • L-KYNURENINE USP/EP/BP
  • N-Acetyltryptophan EP Impurity C
  • Benzenebutanoic acid, α,2-diamino-γ-oxo-, (αS)-
  • Kynurenine (L)
  • c.?(S)-2-amino-4-(2-aminophenyl)-4-oxobutanoicacid(kynurenine),
  • L-Kynurenine (Tryptophan Impurity)
  • CCRIS 4425
  • β-Anthraniloyl-L-alanine
  • Tryptophan - Impurity C
  • L-Kynurenine, Endogenous AhR agonist
  • 2922-83-0
  • C10H12N2O313H2O
  • C10H12N2O3xH2O
  • Amino Acid
  • BioChemical
  • Metabolomics
  • Metabolites and Cofactors on the Metabolic Pathways Chart
  • Metabolic Pathways
  • Amino Acids
  • Amino Acids
  • Biochemistry
  • non-Proteinorganic Amino Acids