4-Methoxycyclohexanon
- Product Name
- 4-Methoxycyclohexanon
- CAS No.
- 13482-23-0
- Chemical Name
- 4-Methoxycyclohexanon
- Synonyms
- 4-Methoxycyclohexano;4-Methoxycyclohexanon;p-Methoxycyclohexanone;4-Metho×ycyclohe×anone;Cyclohexanone, 4-methoxy-;4-Methoxycyclohexan-1-one;4-methoxycyclohexanone, 98%min;4-methoxycyclohexan-1-one - [M82414]
- CBNumber
- CB61448450
- Molecular Formula
- C7H12O2
- Formula Weight
- 128.17
- MOL File
- 13482-23-0.mol
4-Methoxycyclohexanon Property
- Boiling point:
- 189 ºC
- Density
- 0.98
- refractive index
- 1.4560
- Flash point:
- 69 ºC
- storage temp.
- 2-8°C
- solubility
- soluble in Chloroform, Ethyl Acetate, Methanol
- form
- liquid
- color
- Clear, pale yellow
- InChI
- InChI=1S/C7H12O2/c1-9-7-4-2-6(8)3-5-7/h7H,2-5H2,1H3
- InChIKey
- XADCKKKOYZJNAR-UHFFFAOYSA-N
- SMILES
- C1(=O)CCC(OC)CC1
Safety
- HS Code
- 2914500090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M262380
- Product name
- 4-Methoxycyclohexanone
- Packaging
- 1g
- Price
- $80
- Updated
- 2021/12/16
- Product number
- M15675
- Product name
- 4-Methoxycyclohexanone
- Purity
- 97%
- Packaging
- 5g
- Price
- $98
- Updated
- 2021/12/16
- Product number
- M15675
- Product name
- 4-Methoxycyclohexanone
- Purity
- 97%
- Packaging
- 1g
- Price
- $24
- Updated
- 2021/12/16
- Product number
- 075943
- Product name
- 4-Methoxycyclohexanone
- Purity
- 95+%
- Packaging
- 1g
- Price
- $138
- Updated
- 2021/12/16
- Product number
- OR480813
- Product name
- 4-Methoxycyclohexanone
- Purity
- 95%
- Packaging
- 1g
- Price
- $151
- Updated
- 2021/12/16
4-Methoxycyclohexanon Chemical Properties,Usage,Production
Uses
4-Methoxycyclohexanone is a substituted cyclohexanone used in the preparation of various organic compounds such as antitumor agents.
Synthesis
150-76-5
13482-23-0
The general procedure for the synthesis of p-methoxycyclohexanone from p-hydroxyanisole is as follows: 7 g of palladium-carbon catalyst and 1 g of borax were added to an autoclave, followed by 150 g of methylcyclohexane and 100 g of p-hydroxyanisole. The reaction was slowly heated to 100 °C and hydrogen was introduced into the system until the pressure reached 1.0 MPa, and stirring was started. When the pressure dropped to 0.5 MPa, hydrogen was supplemented to 1.0 MPa, keeping the reaction pressure in the range of 0.7-1.0 MPa. Continuously monitor the hydrogen consumption, and after the hydrogen consumption stops for a period of time, take samples for reaction process monitoring. When the remaining amount of raw material is less than 1%, the reaction is judged to be complete. The reaction mixture was cooled to 30°C and filtered to remove the catalyst. The filtrate was evaporated to remove the solvent and subsequently distilled under reduced pressure to give 92 g of p-methoxycyclohexanone in 90% yield.
References
[1] Patent: CN107827881, 2018, A. Location in patent: Paragraph 0034; 0035
[2] Patent: US5886232, 1999, A
[3] Tetrahedron Letters, 1994, vol. 35, # 39, p. 7151 - 7154
[4] Journal of Organic Chemistry, 1961, vol. 26, p. 2633 - 2640
[5] Tetrahedron, 1976, vol. 32, p. 2589 - 2594
4-Methoxycyclohexanon Preparation Products And Raw materials
Raw materials
Preparation Products
4-Methoxycyclohexanon Suppliers
- Tel
- --
- Fax
- --
- mark.witterholt@minakem.com
- Country
- France
- ProdList
- 200
- Advantage
- 30
View Lastest Price from 4-Methoxycyclohexanon manufacturers
- Product
- 4-Methoxycyclohexanone 13482-23-0
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-24
- Product
- 4-Methoxycyclohexanone 13482-23-0
- Price
- US $0.00/kg
- Min. Order
- 100kg
- Purity
- 96%min
- Supply Ability
- 1 tons
- Release date
- 2024-09-10
- Product
- 4-Methoxycyclohexanon 13482-23-0
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99.9%
- Supply Ability
- 10000tons
- Release date
- 2023-08-23