ChemicalBook > CAS DataBase List > 1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane

1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane

Product Name: 1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane
CAS No.: 175854-39-4
Chemical Name: 1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane
Synonyms: TriBoc-Cyclen;Cyclen Derivatives 1;N,N',N''-tris-Boc-cyclen;1,4,7-Tri-Boc-1,4,7,10-tetraazacyclododecane;1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane;1,4,7-tris-Boc-1,4,7,11-tetraaza-cyclododecane;1,4,7-tert butoxycarbonyl-1,4,7,10-tetraazacyclododecane;1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane (TriBOC-Cyclen);Tri-tert-Butyl 1,4,7,10-tetraazacyclododecane-1,4,7-tricarboxylate;Tri-tert-butyl 1,4,7,10-tetraazacyclotetradecane-1,4,7-tricarboxylate
CBNumber: CB61466593
Molecular Formula: C23H44N4O6
Formula Weight: 472.62
MOL File: 175854-39-4.mol

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1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane Property

Melting point:: 72-73℃
Boiling point:: 542.8±35.0 °C(Predicted)
Density: 1.065
storage temp.: 2-8°C
pka: 9.52±0.20(Predicted)
form: powder
Sensitive: Hygroscopic
InChI: InChI=1S/C23H44N4O6/c1-21(2,3)31-18(28)25-12-10-24-11-13-26(19(29)32-22(4,5)6)15-17-27(16-14-25)20(30)33-23(7,8)9/h24H,10-17H2,1-9H3
InChIKey: ZXASHTYJQJMCQR-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCNCCN(C(OC(C)(C)C)=O)CCN(C(OC(C)(C)C)=O)CC1

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 711683
Product name: 1,4,7-Tri-Boc-1,4,7,10-tetraazacyclododecane
Purity: 98%
Packaging: 250mg
Price: $495
Updated: 2022/05/15

Usbiological

Product number: 291462
Product name: 1,4,7-tri-Boc-1,4,7,10-tetraaza-cyclododecane
Packaging: 250mg
Price: $372
Updated: 2021/12/16

TRC

Product number: B662085
Product name: Tris-BOC-Cyclen
Packaging: 1g
Price: $580
Updated: 2021/12/16

Ark Pharm

Product number: AK103030
Product name: Tri-tert-Butyl1,4,7,10-tetraazacyclododecane-1,4,7-tricarboxylate
Purity: 97%
Packaging: 250mg
Price: $26
Updated: 2021/12/16

Ark Pharm

Product number: AK103030
Product name: Tri-tert-Butyl1,4,7,10-tetraazacyclododecane-1,4,7-tricarboxylate
Purity: 97%
Packaging: 1g
Price: $86
Updated: 2021/12/16

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1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

Building block used to attach the Cyclen azacrown to a molecular scaffold, building block for a trifold cyclen Zn complex as phosphate dianion receptor in aqueous solution

Synthesis

24424-99-5

294-90-6

175854-39-4

A solution of chloroform (10 mL) of di-tert-butyl dicarbonate (1.77 g, 8.12 mmol) was slowly added dropwise through a constant pressure dropping funnel to a solution of chloroform (40 mL) containing rotundin (0.51 g, 2.90 mmol) and triethylamine (1.25 mL, 8.99 mmol). The reaction mixture was stirred at room temperature overnight and then concentrated by rotary evaporator. The resulting crude product was purified by silica gel column chromatography using gradient elution from ethyl acetate to 5% methanol/dichloromethane to afford the target compound 1,4,7-tri-tert-butoxycarbonyl-1,4,7,10-tetraazacyclododecane as a white solid (1.02 g, 80% yield). The product characterization data were in agreement with literature reports.

References

[1] Journal of Materials Chemistry, 2012, vol. 22, # 36, p. 18784 - 18787
[2] Journal of the American Chemical Society, 2004, vol. 126, # 30, p. 9248 - 9256
[3] RSC Advances, 2016, vol. 6, # 28, p. 23645 - 23652
[4] Journal of Organic Chemistry, 2005, vol. 70, # 1, p. 115 - 123
[5] Chemical Communications, 2011, vol. 47, # 21, p. 6036 - 6038

1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 1,4,7-tri-Boc-1,4,7,10-Tetraazacyclododecane 175854-39-4
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-06-27

Xian confluore Biological Technology Co., Ltd.

Product: Tris-BOC-Cyclen 175854-39-4
Price: US $0.00/g
Min. Order: 5g
Purity: >95.00%
Supply Ability: 5g
Release date: 2024-04-01

Honest Joy Holdings Limited

Product: 1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane 175854-39-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.7%
Supply Ability: 100 tons
Release date: 2022-01-14

175854-39-4, 1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecaneRelated Search:

Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetate HydrobroMide TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD CYCLODODECANE 1,4-BIS-BOC-1,4,7-TRIAZAHEPTANE 1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane

1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane

1,4,7-Tri-Boc-1,4,7,10-tetraazacyclododecane

N,N',N''-tris-Boc-cyclen

1,4,7,10-Tetraazacyclododecane-1,4,7-tricarboxylic acid, tris(1,1-diMethylethyl) ester

TriBoc-Cyclen

Tri-tert-butyl 1,4,7,10-tetraazacyclotetradecane-1,4,7-tricarboxylate

Tri-tert-Butyl 1,4,7,10-tetraazacyclododecane-1,4,7-tricarboxylate

1,4,7,10-Tetraazacyclododecane-1,4,7-tricarboxylic acid, 1,4,7-tris(1,1-dimethylethyl) ester

1,4,7-tris-Boc-1,4,7,11-tetraaza-cyclododecane

Cyclen Derivatives 1

1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane (TriBOC-Cyclen)

1,4,7-tert butoxycarbonyl-1,4,7,10-tetraazacyclododecane

175854-39-4

C23H44N4O6