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CORTICOTROPIN RELEASING FACTOR ANTAGONIST

Product Name
CORTICOTROPIN RELEASING FACTOR ANTAGONIST
CAS No.
90880-23-2
Chemical Name
CORTICOTROPIN RELEASING FACTOR ANTAGONIST
CBNumber
CB61472927
Molecular Formula
C166H274N46O53S2
Formula Weight
0
MOL File
Mol file
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CORTICOTROPIN RELEASING FACTOR ANTAGONIST Property

storage temp. 
Desiccate at -20°C
solubility 
Soluble to 1 mg/ml in 0.1% TFA
form 
Powder
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology
Product number
B5076
Product name
α-helicalCRF9-41
Packaging
500ug
Price
$448
Updated
2021/12/16
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CORTICOTROPIN RELEASING FACTOR ANTAGONIST Chemical Properties,Usage,Production

Uses

α-Helical CRF(9-41) is a competitive CRF2 receptor antagonist with KB of ~100 nM. α-Helical CRF(9-41) is also a partial agonist of CRF1 receptor with an EC50 of 140 nM[1][2].

References

[1] Sonia Tucci, et al. Corticotropin releasing factor antagonist, alpha-helical CRF(9-41), reverses nicotine-induced conditioned, but not unconditioned, anxiety. Psychopharmacology (Berl). 2003 May;167(3):251-6. DOI:10.1007/s00213-003-1403-4
[2] Smart D, et al. Characterisation using microphysiometry of CRF receptor pharmacology. Eur J Pharmacol. 1999 Aug 27;379(2-3):229-35. DOI:10.1016/s0014-2999(99)00506-3

CORTICOTROPIN RELEASING FACTOR ANTAGONIST Preparation Products And Raw materials

Raw materials

Preparation Products

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CORTICOTROPIN RELEASING FACTOR ANTAGONIST Suppliers

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