Clinafloxacin

Product Name: Clinafloxacin
CAS No.: 105956-97-6
Chemical Name: Clinafloxacin
Synonyms: CI-960;PD-127391;Aids007759;Aids-007759;Clinfloxacin;CLINAFLOXACIN;Colinflosaxin;Clinofloxacin;Clinafloxacin (AM-1091;Clinafloxacin USP/EP/BP
CBNumber: CB6148236
Molecular Formula: C17H17ClFN3O3
Formula Weight: 365.79
MOL File: 105956-97-6.mol

More

Less

Clinafloxacin Property

Melting point:: 253-258 C
Boiling point:: 592.3±50.0 °C(Predicted)
Density: 1.573±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: Acetic Acid (Slightly), DMSO (Slightly)
form: Solid
pka: 6.39±0.50(Predicted)
color: Pale Beige
InChI: InChI=1S/C17H17ClFN3O3/c18-13-14-10(5-12(19)15(13)21-4-3-8(20)6-21)16(23)11(17(24)25)7-22(14)9-1-2-9/h5,7-9H,1-4,6,20H2,(H,24,25)
InChIKey: QGPKADBNRMWEQR-UHFFFAOYSA-N
SMILES: N1(C2CC2)C2=C(C=C(F)C(N3CCC(N)C3)=C2Cl)C(=O)C(C(O)=O)=C1
CAS DataBase Reference: 105956-97-6(CAS DataBase Reference)
EPA Substance Registry System: Clinafloxacin (105956-97-6)

More

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-63
Safety Statements: 26-36-36/37
RTECS: VB1800600

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Precautionary statements: P281Use personal protective equipment as required.

More

Less

N-Bromosuccinimide Price

TRC

Product number: C579003
Product name: Clinafloxacin
Packaging: 50mg
Price: $165
Updated: 2021/12/16

ApexBio Technology

Product number: A8400
Product name: ClinafloxacinCI96AM1091
Packaging: 50mg
Price: $100
Updated: 2021/12/16

ChemScene

Product number: CS-2633
Product name: Clinafloxacin
Purity: 98.53%
Packaging: 25mg
Price: $130
Updated: 2021/12/16

ChemScene

Product number: CS-2633
Product name: Clinafloxacin
Purity: 98.53%
Packaging: 50mg
Price: $220
Updated: 2021/12/16

Matrix Scientific

Product number: 091183
Product name: 7-(3-Aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Purity: 95+%
Packaging: 1g
Price: $240
Updated: 2021/12/16

More

Less

Clinafloxacin Chemical Properties,Usage,Production

Uses

Antibacterial.

Uses

Clinafloxacin is a fluoroquinolone that inhibits both DNA gyrase and topoisomerase IV.

Definition

ChEBI: 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-3-quinolinecarboxylic acid is a member of quinolines.

in vivo

Clinafloxacin is very effective for the therapy of penicillin-resistant, ciprofloxacin-susceptible pneumococcal meningitis in the rabbit model. With the CS strain (2349)(Clinafloxacin MIC=0.12 μg/ml), at a dose of 10 mg/kg and 20 mg/kg per day Clinafloxacin achieves an initial reduction at 6 hr. Both are bactericidal at this point but presents regrowth at 24 hr, and the final reduction at 24 hr in mean log cfu/ml is 22.30 and 23.83, respectively. However, With the CR strain (4371)(Clinafloxacin MIC=0.5 μg/ml), Clinafloxacin even at 20 mg/kg per day does not decrease bacterial titers at any time point in this rabbit model of meningitis^[3].

IC 50

Quinolone

Clinafloxacin Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Clinafloxacin Suppliers

China 160 Europe 4 Germany 1 India 3 South Korea 1 United Kingdom 5 United States 19 Global 193

Leancare Ltd.

Tel: --
Fax: --
Email: enquiry@leancare.co.uk
Country: United Kingdom
ProdList: 6446
Advantage: 42

CARBONE SCIENTIFIC CO.,LTD

Tel: --
Fax: --
Email: sales@carbonesci.com
Country: United Kingdom
ProdList: 6666
Advantage: 30

MOLEKULA Ltd.

Tel: --
Fax: --
Email: kevinbanks@molekula.com
Country: United Kingdom
ProdList: 6140
Advantage: 66

UK GREEN SCIENTIFIC CO.,LIMITED

Tel: --
Fax: --
Email: sales@gs-chem.com
Country: United Kingdom
ProdList: 6098
Advantage: 47

Sequoia Research Products Ltd.

Tel: --
Fax: --
Email: sales@seqchem.com
Country: United Kingdom
ProdList: 3113
Advantage: 69

More

Less

View Lastest Price from Clinafloxacin manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Clinafloxacin 105956-97-6
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-25

Shanghai Biolang Biotechnology Co., Ltd.

Product: Clinafloxacin 105956-97-6
Price: US $9.90-7.70/g
Min. Order: 10g
Purity: 99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets，Customiz
Supply Ability: 1000kgs
Release date: 2022-02-22

Dideu Industries Group Limited

Product: Clinafloxacin 105956-97-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-19

105956-97-6, ClinafloxacinRelated Search:

Povidone iodine N-Vinyl-2-pyrrolidone Quinclorac ALTRENOGEST Glycine Clindamycin Polyvinylpyrrolidone 6-Aminocaproic acid Quinhydrone Clindamycin hydrochloride N-Methyl-2-pyrrolidone Ethoxyquin Clindamycin phosphate TROVAFLOXACIN Gatifloxacin Gemifioxacin Tris(hydroxymethyl)aminomethane Sparfloxacin

3-Quinolinecarboxylic acid, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-

6-Fluoro-8-chloro-1-cyclopropyl-7-(3-aminopyrrolidin-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

7-(3-Aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

CI-960

PD-127391

105956-99-8 (Hydrochloride)

7-(3-Amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-8-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, monohydrochloride

Aids007759

Aids-007759

7-(3-AMinopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

CLINAFLOXACIN

7-(3-Aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxyli

7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-8-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-3-quinolinecarboxylic acid

Clinafloxacin CI96 AM1091

7-(3-Aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carbox

7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-Quinolin-3-carboxylic acid

7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydroxy-4-oxo-3-quinolinecarboxylic acid

Colinflosaxin

Clindamycin hydrochloride`Clinafloxacin

Clinafloxacin USP/EP/BP

Clinafloxacin (AM-1091

Clinfloxacin

ClinafloxacinQ: What is Clinafloxacin Q: What is the CAS Number of Clinafloxacin

Clinofloxacin

Clinafloxacin in MeOH with 0.04M NaOH

105956-97-6

C17H17ClFN3O3