ChemicalBook > CAS DataBase List > LAZABEMIDE

LAZABEMIDE

Product Name: LAZABEMIDE
CAS No.: 103878-84-8
Chemical Name: LAZABEMIDE
Synonyms: Ro-19-6327;LAZABEMIDE;Ro 19-6327/000;Lazabemide hydrate;Ro 19-6327 hydrate;LAZABEMIDE HYDROCHLORIDE;N-(2-Aminoethyl)-5-chloropicolinamide;N-(2-aminoethyl)-5-chloropyridine-2-carboxamide;N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide;2-PyridinecarboxaMide, N-(2-aMinoethyl)-5-chloro-
CBNumber: CB6149051
Molecular Formula: C8H10ClN3O
Formula Weight: 199.64
MOL File: 103878-84-8.mol

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LAZABEMIDE Property

Boiling point:: 397.4±37.0 °C(Predicted)
Density: 1.286±0.06 g/cm3(Predicted)
storage temp.: room temp
solubility: DMSO: ≥22mg/mL
pka: 12.90±0.46(Predicted)
form: powder
color: white to tan

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Safety

Hazard Codes: Xn
Risk Statements: 22-36
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0042
Product name: Lazabemide hydrate
Purity: ≥97% (HPLC)
Packaging: 10mg
Price: $67.9
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML0042
Product name: Lazabemide hydrate
Purity: ≥97% (HPLC)
Packaging: 50mg
Price: $387
Updated: 2025/07/31

Cayman Chemical

Product number: 11640
Product name: Lazabemide
Purity: ≥98%
Packaging: 5mg
Price: $33
Updated: 2024/03/01

Cayman Chemical

Product number: 11640
Product name: Lazabemide
Purity: ≥98%
Packaging: 10mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 11640
Product name: Lazabemide
Purity: ≥98%
Packaging: 50mg
Price: $254
Updated: 2024/03/01

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LAZABEMIDE Chemical Properties,Usage,Production

Chemical Properties

Lazabemide Monohydrochloride: C8Hl0ClN3O?HCl.[103878-83-7]. Crystallized from methanol-ether, melting point 193-195°C. Partition coefficient (n-octanol pulse): about 0.1. pKa 8.9. acute toxicity LD50 mice (mg/kg): 1000~2000 orally.

Uses

Treatment of Alzheimer’s disease.

Uses

Lazabemide hydrate may be used in cell signaling studies.

brand name

Tempium (Hoffmann-LaRoche).

Biochem/physiol Actions

Lazabemide is effective in treatment of Alzheimer′s disease and in combination with nicotine replacement therapy aids in smoking cessation.

LAZABEMIDE Preparation Products And Raw materials

Raw materials

N-Boc-Ethylenediamine Trifluoroacetic acid 5-Chloropyridine-2-carboxylic acid

Preparation Products

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View Lastest Price from LAZABEMIDE manufacturers

Career Henan Chemical Co

Product: LAZABEMIDE 103878-84-8
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KG
Release date: 2018-08-15

103878-84-8, LAZABEMIDERelated Search:

PHENYLENDIAMINE Tetramethrin Lenalidomide LAZABEMIDE 5-Chloropyridine-2-carboxamide PYRIDINE-2-CARBOXYLIC ACID (2-AMINO-ETHYL)-AMIDE N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid 1-(5-CHLOROPYRIDIN-2-YL)METHANAMINE 5-CHLORO-2-FORMYLPYRIDINE

LAZABEMIDE

LAZABEMIDE HYDROCHLORIDE

N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide

N-(2-aminoethyl)-5-chloropyridine-2-carboxamide

Ro-19-6327

2-PyridinecarboxaMide, N-(2-aMinoethyl)-5-chloro-

Ro 19-6327/000

Lazabemide hydrate

N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrate

Ro 19-6327 hydrate

N-(2-Aminoethyl)-5-chloropicolinamide

103878-84-8