N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid

Product Name: N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
CAS No.: 103878-83-7
Chemical Name: N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
Synonyms: TeMpiuM;Ro 19-6327/001;JMFKTFLARGGXCC-UHFFFAOYSA-N;N-(2-Aminoethyl)-5-chlor-2-pyridincarbox;N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid;N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride;2-PyridinecarboxaMide, N-(2-aMinoethyl)-5-chloro-, Monohydrochloride;ichemia,Lazabemide,DOPAC,MAO,radical generation,Ro 19-6327,disease,alzheimer′s,Inhibitor,inhibit,Lazabemide hydrochloride,Monoamine Oxidase,smoking cessation,parkinson
CBNumber: CB11448718
Molecular Formula: C8H10ClN3O.HCl
Formula Weight: 0
MOL File: 103878-83-7.mol

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N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Property

Melting point:: 193-195°
storage temp.: Desiccate at RT
solubility: Soluble to 100 mM in water and to 100 mM in DMSO
form: Powder
pka: 8.9(at 25℃)

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Safety

Toxicity: LD50 orally in mice: 1000-2000 mg/kg (Imhof, Kyburz, 1986)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: L215258
Product name: LazabemideHydrochloride
Packaging: 50mg
Price: $305
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003133
Product name: LAZABEMIDE HYDROCHLORIDE
Purity: 95.00%
Packaging: 10MG
Price: $648.83
Updated: 2021/12/16

ApexBio Technology

Product number: B7064
Product name: Lazabemidehydrochloride
Packaging: 50mg
Price: $795
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003133
Product name: LAZABEMIDE HYDROCHLORIDE
Purity: 95.00%
Packaging: 50MG
Price: $976.27
Updated: 2021/12/16

ApexBio Technology

Product number: B7064
Product name: Lazabemidehydrochloride
Packaging: 10mg
Price: $196
Updated: 2021/12/16

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N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Chemical Properties,Usage,Production

Uses

Treatment of Alzheimer’s disease.

Uses

Lazabemide Hydrochloride is a reversible and selective inhibitor of MAO-A and MAO-B, both of which oxidatively deaminate neurotransmitter and xenobiotic amines.

Definition

ChEBI: Lazabemide hydrochloride is a pyridinecarboxamide.

brand name

Tempium (Hoffmann-LaRoche).

Biological Activity

Selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC 50 values are 0.03 and > 100 μ M for MAO-B and MAO-A respectively). Inhibits monoamine uptake at high concentrations (IC 50 values are 86, 123 and > 500 μ M for noradrenalin, serotonin and dopamine uptake respectively).

storage

Desiccate at RT

N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Suppliers

China 17 United Kingdom 1 United States 4 USA 1 Global 23

3B Pharmachem (Wuhan) International Co.,Ltd.

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103878-83-7, N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochloridRelated Search:

Methylamine hydrochloride Cysteamine hydrochloride 1-(5-CHLOROPYRIDIN-2-YL)METHANAMINE METHYLPYRIDIN-2-YLMETHYLAMINE DIHYDROCHLORIDE 5-CHLORO-2-FORMYLPYRIDINE LAZABEMIDE 5-Chloropyridine-2-carboxamide PYRIDINE-2-CARBOXYLIC ACID (2-AMINO-ETHYL)-AMIDE N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid

N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid

2-PyridinecarboxaMide, N-(2-aMinoethyl)-5-chloro-, Monohydrochloride

Ro 19-6327/001

TeMpiuM

JMFKTFLARGGXCC-UHFFFAOYSA-N

N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride

N-(2-Aminoethyl)-5-chlor-2-pyridincarbox

ichemia,Lazabemide,DOPAC,MAO,radical generation,Ro 19-6327,disease,alzheimer′s,Inhibitor,inhibit,Lazabemide hydrochloride,Monoamine Oxidase,smoking cessation,parkinson

103878-83-7

C8H10ClN3OHCl

Monoamine Oxidase