6-aminotetralin-2,3-diol
- Product Name
- 6-aminotetralin-2,3-diol
- CAS No.
- 13575-86-5
- Chemical Name
- 6-aminotetralin-2,3-diol
- Synonyms
- ADTN hydrobromide;6-aminotetralin-2,3-diol;6,7-Dihydroxy-2-aminotetraline hydrobromide;Aminotetraline hydrobromide, 6,7-Dihydroxy-2-;6-Amino-5,6,7,8-tetrahydro-2,3-naphthalenediolhydrobromide;(+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthaleneHydrobromide
- CBNumber
- CB61513738
- Molecular Formula
- C10H13NO2
- Formula Weight
- 0
- MOL File
- 13575-86-5.mol
6-aminotetralin-2,3-diol Property
- Melting point:
- 270-271 °C
- storage temp.
- 2-8°C
- solubility
- Soluble in Water (up to 25 mg/ml)
- form
- solid
- color
- Tan
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 week.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 23866
- Product name
- (±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (hydrobromide)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $40
- Updated
- 2024/03/01
- Product number
- 23866
- Product name
- (±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (hydrobromide)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $74
- Updated
- 2024/03/01
- Product number
- 23866
- Product name
- (±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (hydrobromide)
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $177
- Updated
- 2024/03/01
- Product number
- 23866
- Product name
- (±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (hydrobromide)
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $311
- Updated
- 2024/03/01
- Product number
- A610023
- Product name
- (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthaleneHydrobromide
- Packaging
- 1mg
- Price
- $90
- Updated
- 2021/12/16
6-aminotetralin-2,3-diol Chemical Properties,Usage,Production
Description
6,7-ADTN HBr (13575-86-5) is a broad spectrum dopamine receptor agonist.1,2? Demonstrates a marked selectivity for the human dopamine D3 receptor.3 6,7-ADTN and psychostimulants such as cocaine and amphetamine reduce excitatory synaptic transmission in the nucleus accumbens by activating presynaptic dopamine receptors.4
Uses
(+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide is a dopamine receptor agonist in Tribolium castaneum.
References
1) List et al. (1982), Striatal binding of 2-amino-6,7-[3H]dihydroxy-1,2,3,4-tetrahydronaphthalene to two dopaminergic sites distinguished by their low and high affinity for neuroleptics; J. Neurosci., 2 895 2) Templeton et al. (1982), Binding of [3H]ADTN to rat striatal membranes; Biochem. Pharmacol., 31 1629 3) Freedman et al. (1994), Expression and pharmacological characterization of the human D3 dopamine receptor; Curr. J. Pharmacol. Exp. Ther., 268 417 4) Nicola et al. (1996), Psychostimulants depress excitatory synaptic transmission in the nucleus accumbens via presynaptic D1-like dopamine receptors; J. Neurosci., 16 1591