6-chloro-1H-pyrazolo[3,4-b]pyridine
- Product Name
- 6-chloro-1H-pyrazolo[3,4-b]pyridine
- CAS No.
- 63725-51-9
- Chemical Name
- 6-chloro-1H-pyrazolo[3,4-b]pyridine
- Synonyms
- 6-chloro-1H-pyrazolo[3;7-Aza-6-chloro-1H-indazole;6-Chloro-1H-pyrazolo[3,4-...;6-Chlor-1H-pyrazolo<3,4-b>pyridin;6-Chloro-1H-Pyrazol[3,4-b]pyridine;6-chloro-1H-pyrazolo[3,4-b]pyridine;1H-Pyrazolo[3,4-b]pyridine, 6-chloro-;6-Chloro-1H-pyrazolo[3,4-b]pyridine 98%
- CBNumber
- CB61515828
- Molecular Formula
- C6H4ClN3
- Formula Weight
- 153.57
- MOL File
- 63725-51-9.mol
6-chloro-1H-pyrazolo[3,4-b]pyridine Property
- Boiling point:
- 262℃
- Density
- 1.61
- Flash point:
- 113℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 5.20±0.40(Predicted)
- form
- solid
- color
- Yellow-brown
- InChI
- InChI=1S/C6H4ClN3/c7-5-2-1-4-3-8-10-6(4)9-5/h1-3H,(H,8,9,10)
- InChIKey
- NWYLBGYCSAJFCB-UHFFFAOYSA-N
- SMILES
- C12NN=CC1=CC=C(Cl)N=2
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- W7557
- Product name
- 6-Chloro-1H-pyrazolo[3,4-b]pyridine
- Packaging
- 250mg
- Price
- $108
- Updated
- 2021/12/16
- Product number
- W7557
- Product name
- 6-Chloro-1H-pyrazolo[3,4-b]pyridine
- Packaging
- 1g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 3H32-5-A5
- Product name
- 6-Chloro-1H-pyrazolo[3,4-b]pyridine
- Packaging
- 1g
- Price
- $180
- Updated
- 2021/12/16
- Product number
- W7557
- Product name
- 6-Chloro-1H-pyrazolo[3,4-b]pyridine
- Packaging
- 5g
- Price
- $378
- Updated
- 2021/12/16
- Product number
- 3H32-5-A5
- Product name
- 6-Chloro-1H-pyrazolo[3,4-b]pyridine
- Packaging
- 5G
- Price
- $600
- Updated
- 2021/12/16
6-chloro-1H-pyrazolo[3,4-b]pyridine Chemical Properties,Usage,Production
Synthesis
1093880-37-5
63725-51-9
GENERAL STEPS: To a solution of tetrahydrofuran (THF, 30 mL) containing 6-chloro-2-fluoropyridine-3-carbaldehyde (4.0 g, 25.1 mmol) was added hydrazine hydrate (2.515 g, 56.3 mmol). The reaction mixture was heated at 60 °C with stirring for 5 hours. Upon completion of the reaction, the mixture was concentrated and quenched with ice water. The solid formed was collected by filtration and dried under vacuum to afford 6-chloro-1hydro-pyrazolo[3,4-B]pyridine (3.5 g, 92% yield). The product was characterized by 1H NMR (DMSO-d6, 300 MHz): δ 13.8 (s, 1H), 8.32-8.29 (d, 1H), 8.20 (s, 1H), 7.27-7.24 (d, 1H). the LCMS analysis showed a purity of 89.96%, m/z = 153.9 (M + 1).
References
[1] Patent: WO2017/9798, 2017, A1. Location in patent: Page/Page column 66
6-chloro-1H-pyrazolo[3,4-b]pyridine Preparation Products And Raw materials
Raw materials
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View Lastest Price from 6-chloro-1H-pyrazolo[3,4-b]pyridine manufacturers
- Product
- 6-Chloro-1H-pyrazolo[3,4-b]pyridine 63725-51-9
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-25
- Product
- 6-chloro-1H-pyrazolo[3,4-b]pyridine 63725-51-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-17