ChemicalBook > CAS DataBase List > 6-chloro-1H-pyrazolo[3,4-b]pyridine

6-chloro-1H-pyrazolo[3,4-b]pyridine

Product Name
6-chloro-1H-pyrazolo[3,4-b]pyridine
CAS No.
63725-51-9
Chemical Name
6-chloro-1H-pyrazolo[3,4-b]pyridine
Synonyms
6-chloro-1H-pyrazolo[3;7-Aza-6-chloro-1H-indazole;6-Chloro-1H-pyrazolo[3,4-...;6-Chlor-1H-pyrazolo<3,4-b>pyridin;6-Chloro-1H-Pyrazol[3,4-b]pyridine;6-chloro-1H-pyrazolo[3,4-b]pyridine;1H-Pyrazolo[3,4-b]pyridine, 6-chloro-;6-Chloro-1H-pyrazolo[3,4-b]pyridine 98%
CBNumber
CB61515828
Molecular Formula
C6H4ClN3
Formula Weight
153.57
MOL File
63725-51-9.mol
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6-chloro-1H-pyrazolo[3,4-b]pyridine Property

Boiling point:
262℃
Density 
1.61
Flash point:
113℃
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
5.20±0.40(Predicted)
form 
solid
color 
Yellow-brown
InChI
InChI=1S/C6H4ClN3/c7-5-2-1-4-3-8-10-6(4)9-5/h1-3H,(H,8,9,10)
InChIKey
NWYLBGYCSAJFCB-UHFFFAOYSA-N
SMILES
C12NN=CC1=CC=C(Cl)N=2
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
W7557
Product name
6-Chloro-1H-pyrazolo[3,4-b]pyridine
Packaging
250mg
Price
$108
Updated
2021/12/16
AK Scientific
Product number
W7557
Product name
6-Chloro-1H-pyrazolo[3,4-b]pyridine
Packaging
1g
Price
$150
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-5-A5
Product name
6-Chloro-1H-pyrazolo[3,4-b]pyridine
Packaging
1g
Price
$180
Updated
2021/12/16
AK Scientific
Product number
W7557
Product name
6-Chloro-1H-pyrazolo[3,4-b]pyridine
Packaging
5g
Price
$378
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-5-A5
Product name
6-Chloro-1H-pyrazolo[3,4-b]pyridine
Packaging
5G
Price
$600
Updated
2021/12/16
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6-chloro-1H-pyrazolo[3,4-b]pyridine Chemical Properties,Usage,Production

Synthesis

1093880-37-5

63725-51-9

GENERAL STEPS: To a solution of tetrahydrofuran (THF, 30 mL) containing 6-chloro-2-fluoropyridine-3-carbaldehyde (4.0 g, 25.1 mmol) was added hydrazine hydrate (2.515 g, 56.3 mmol). The reaction mixture was heated at 60 °C with stirring for 5 hours. Upon completion of the reaction, the mixture was concentrated and quenched with ice water. The solid formed was collected by filtration and dried under vacuum to afford 6-chloro-1hydro-pyrazolo[3,4-B]pyridine (3.5 g, 92% yield). The product was characterized by 1H NMR (DMSO-d6, 300 MHz): δ 13.8 (s, 1H), 8.32-8.29 (d, 1H), 8.20 (s, 1H), 7.27-7.24 (d, 1H). the LCMS analysis showed a purity of 89.96%, m/z = 153.9 (M + 1).

References

[1] Patent: WO2017/9798, 2017, A1. Location in patent: Page/Page column 66

6-chloro-1H-pyrazolo[3,4-b]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-chloro-1H-pyrazolo[3,4-b]pyridine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
6-Chloro-1H-pyrazolo[3,4-b]pyridine 63725-51-9
Price
US $3.00-9.00/KG
Min. Order
0.1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2025-06-25
Career Henan Chemical Co
Product
6-chloro-1H-pyrazolo[3,4-b]pyridine 63725-51-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KGS
Release date
2019-12-17