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Eprotirome

Product Name
Eprotirome
CAS No.
355129-15-6
Chemical Name
Eprotirome
Synonyms
Kb-2115;eprotirome;Unii-958aq7B6R1;Eprotirome(KB-2115);KB2115 Exclusive;VPCSYAVXDAUHLT-UHFFFAOYSA-N;N-[3,5-Dibromo-4-(4-hydroxy-3-isopropylphenoxy)phenyl]malonamic acid;THR,inhibit,KB 2115,Eprotirome,Inhibitor,KB-2115,Thyroid Hormone Receptor;3-((3,5-Dibromo-4-(4-hydroxy-3-isopropylphenoxy)phenyl)amino)-3-oxopropanoic acid;3-((3,5-Dibromo-4-(4-hydroxy-3-(1-methylethyl)phenoxy)phenyl)amino)-3-oxopropanoic acid
CBNumber
CB61518511
Molecular Formula
C18H17Br2NO5
Formula Weight
487.14
MOL File
355129-15-6.mol
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Eprotirome Property

Boiling point:
596.3±50.0 °C(Predicted)
Density 
1.708
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO:84.0(Max Conc. mg/mL);172.43(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);61.58(Max Conc. mM)
Ethanol:63.5(Max Conc. mg/mL);130.35(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.03(Max Conc. mM)
form 
A crystalline solid
pka
3.16±0.32(Predicted)
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10011054
Product name
KB2115
Purity
≥98%
Packaging
25mg
Price
$190
Updated
2024/03/01
Cayman Chemical
Product number
10011054
Product name
KB2115
Purity
≥98%
Packaging
50mg
Price
$286
Updated
2024/03/01
Cayman Chemical
Product number
10011054
Product name
KB2115
Purity
≥98%
Packaging
100mg
Price
$475
Updated
2024/03/01
Cayman Chemical
Product number
10011054
Product name
KB2115
Purity
≥98%
Packaging
500μg
Price
$75
Updated
2021/12/16
Cayman Chemical
Product number
10011054
Product name
KB2115
Purity
≥98%
Packaging
1mg
Price
$143
Updated
2021/12/16
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Eprotirome Chemical Properties,Usage,Production

Uses

Eprotirome, is a liver-selective thyroid hormone receptor agonist.

in vivo

Eprotirome is a liver-selective thyroid hormone receptor agonist. Histological analysis of livers from mice treated with Eprotirome reveals that Eprotirome elicits a near complete elimination of lipid filled vacuoles that are characteristic of the livers from untreated control mice. Eprotirome treated mice also exhibit increased fasting glucose, but Eprotirome does not increase fasting insulin levels. Glucose levels of mice treated with Eprotirome continues to increase over time, leading to pronounced hyperglycemia by the end of the study. Temperature of mice treated with Eprotirome is decreased relative to untreated control mice[1].

Eprotirome Preparation Products And Raw materials

Raw materials

Preparation Products

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Eprotirome Suppliers

355129-15-6, EprotiromeRelated Search:


  • eprotirome
  • N-[3,5-Dibromo-4-(4-hydroxy-3-isopropylphenoxy)phenyl]malonamic acid
  • 3-((3,5-Dibromo-4-(4-hydroxy-3-(1-methylethyl)phenoxy)phenyl)amino)-3-oxopropanoic acid
  • Kb-2115
  • Unii-958aq7B6R1
  • Propanoic acid,3-[[3,5-dibroMo-4-[4-hydroxy-3-(1-Methylethyl)phenoxy]phenyl]aMino]-3-oxo-
  • VPCSYAVXDAUHLT-UHFFFAOYSA-N
  • KB2115 Exclusive
  • 3-((3,5-Dibromo-4-(4-hydroxy-3-isopropylphenoxy)phenyl)amino)-3-oxopropanoic acid
  • THR,inhibit,KB 2115,Eprotirome,Inhibitor,KB-2115,Thyroid Hormone Receptor
  • Eprotirome(KB-2115)
  • 355129-15-6