(+)-Taddol

Product Name: (+)-Taddol
CAS No.: 93379-49-8
Chemical Name: (+)-Taddol
Synonyms: ((4S,5S);97.0%(LC);(+)-TADDOL;(S,S)-taddol;SEEBACH REAGENT;bis(diphenylmethanol);(4S,5S)-2,2-Dimethyl-α;(+)-4,5-Bis[hydroxy(diphenyL;meso-2,3-Diphenylsuccinonitrile>(+)-2,3-O-ISOPROPYLIDENE-1,1,4,4-TE
CBNumber: CB6152969
Molecular Formula: C31H30O4
Formula Weight: 466.57
MOL File: 93379-49-8.mol

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(+)-Taddol Property

Melting point:: 193-196 °C(lit.)
alpha: -62.6 º (c=1 in chloroform)
Boiling point:: 633.2±50.0 °C(Predicted)
Density: 1.200±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
form: powder to crystal
pka: 12.28±0.29(Predicted)
color: White to Almost white
optical activity: [α]19/D +67°, c = 1 in chloroform
BRN: 4724097
InChIKey: RNSJHECWLNVNFE-LOYHVIPDSA-N
CAS DataBase Reference: 93379-49-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 264997
Product name: (4S,5S)-2,2-Dimethyl-α,α,α′,α′-tetraphenyldioxolane-4,5-dimethanol
Purity: 97%
Packaging: 1g
Price: $94.3
Updated: 2022/05/15

TCI Chemical

Product number: B2048
Product name: (+)-4,5-Bis[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolane
Purity: >97.0%(HPLC)
Packaging: 1g
Price: $95
Updated: 2024/03/01

TCI Chemical

Product number: B2048
Product name: (+)-4,5-Bis[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolane
Purity: >97.0%(HPLC)
Packaging: 5g
Price: $262
Updated: 2024/03/01

Strem Chemicals

Product number: 08-1258
Product name: (4S,5S)-2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-4,5-dimethanol, 98% (99% ee)
Packaging: 1g
Price: $46
Updated: 2024/03/01

TRC

Product number: T779313
Product name: (+)-TADDOL
Packaging: 50mg
Price: $60
Updated: 2021/12/16

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(+)-Taddol Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

Ligand for enantioselective Lewis-acid mediated Diels-Alder, allyltitanation of aldehydes, and Michael-Mukaiyama additions promoted by chiral Ti-complexes.

Preparation

Preparative Methods of (4R,5R)-2,2-Dimethyl-4,5-bis(hydroxydiphenylmethyl)-1,3-dioxolane: chiral titanates are usually prepared by mixing dichlorodiisopropoxytitanium and a chiral 1,4-diol in toluene. Other solvents such as ether and dichloromethane can also be employed. The alcohol exchange reaction takes place immediately at rt. Wherever necessary, liberated isopropyl alcohol is removed by azeotropic removal with toluene. The chiral 1,4-diols are prepared from dimethyl (or diethyl) tartrate by a two-step procedure comprising acetalization followed by the addition of an aryl Grignard reagent.

storage

Chiral titanates are usually prepared just before use under argon atmosphere. Care should be taken to avoid moisture, especially when a catalytic amount of the reagent is used.

(+)-Taddol Preparation Products And Raw materials

Raw materials

p-Toluenesulfonic acid Bromobenzene Tetrahydrofuran Ethyl acetate Dichloromethane Methanol L(+)-Tartaric acid

Preparation Products

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(+)-Taddol Suppliers

Americas 1 China 110 Europe 1 France 1 Germany 4 India 3 Japan 2 Switzerland 1 The Netherlands 1 United Kingdom 10 United States 21 Global 155

Tokyo Chemical Industry UK Ltd.

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Align Chemical Limited

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CARBONE SCIENTIFIC CO.,LTD

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MOLEKULA Ltd.

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VWR International

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View Lastest Price from (+)-Taddol manufacturers

Career Henan Chemical Co

Product: (+)-Taddol 93379-49-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%-99%
Supply Ability: 100KG
Release date: 2019-08-29

93379-49-8, (+)-TaddolRelated Search:

Dichlorodiphenylsilane Dimethyl phthalate 1,5-Diphenylcarbazide 1,3-Diphenyl-2-thiourea 3,4'-DIAMINODIPHENYLMETHANE Chlorodiphenylphosphine Diphenyldimethoxysilane Dimethyl sulfide Dimethyl fumarate N,N-Dimethylformamide Dimethyl ether Dimethyl sulfoxide 2,2-Dimethyl-1,3-dioxolane-4-methanol ETHANE 1,3-Dioxolane 2,5-Dimethyl-2,5-hexanediol 2,2,4-TRIMETHYL-1,3-DIOXOLANE (R)-(-)-4-PHENYL-2-BUTANOL

(+)-4,5-BIS[HYDROXY(DIPHENYL)METHYL]-2,2-DIMETHYL-1,3-DIOXOLANE

(4S,5S)-2,2-DIMETHYL-ALPHA,ALPHA,ALPHA',ALPHA'-TETRAPHENYLDIOXOLANE-4,5-DIMETHANOL

(4S,5S)-4,5-BIS(DIPHENYLHYDROXYMETHYL)-2,2-DIMETHYL-DIOXOLANE

(+)-2,3-O-ISOPROPYLIDENE-1,1,4,4-TETRAPHENYL-D-THREITOL

(2S,3S)-(+)-1,1,4,4-TETRAPHENYL-2,3-(2-PROPYLIDENEDIOXY)-BUTANE-1,4-DIOL

(2S,3S)-2,3-O-ISOPROPYLIDENE-1,1,4,4-TETRAPHENYL-1,2,3,4-BUTANETETROL

(2S,3S)-(+)-4,5-BIS(DIPHENYLHYDROXYMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

(+)-TADDOL

SEEBACH REAGENT

1,3-Dioxolane-4,5-dimethanol, 2,2-dimethyl-.alpha.,.alpha.,.alpha.,.alpha.-tetraphenyl-, (4S,5S)-

(4s,5s)-2,2-dimethyl-α,α,α',α'-tetraphenyldioxolane-4,5-dimethanol

(+)-Taddol (2S,3S)-(-)-4,5-Bis(diphenylhydroxymethyl)-2,2-dimethyl-1,3-dioxolane

(+)-TRANS-4,5-BIS-(DIPHENYL-HYDROXYMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

(+)-TRANS-ALPHA,ALPHA'-(2,2-DIMETHYL-1,3-DIOXOLANE-4,5-DIYL)BIS(DIPHENYLMETHANOL)

(+)-trans-A,A-(2,2-dimethyl-1,3-dioxolane -4,5-D

Bishydroxydiphenylmethyldimethyldioxolane

1,1,4,4-Tetraphenyl-2,3,0-isopropylidene-D-threitol

(4S,5S)-2,2-Dimethyl-alpha,alpha,alpha',alpha'-tetraphenyldioxolane-4,5-dimethan

(2,2-)Dimethy-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol)

(4S,5S)-2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane- 4,5-dimethanol

((4S,5S)

-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)

bis(diphenylmethanol)

(4S,5S)-2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane- 4,5-dimethanol,99%e.e.

1,1,4,4-Tetraphenyl-2,3-O-isopropylidene-L-threitol

[(4S,5S)-5-[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolan-4-yl]-diphenylmethanol

(+)-2,3-O-ISOPROPYLIDENE-1,1,4,4-TE

(4S,5S)-2,2-DIMETHYL-A,A,A'',A'',-TETRAPHENYLDIOXOLANE-4,5-DIMETHANOL

(+)-trans-α,α'-(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(diphenlmethanol)

(2,2-dimethyl)-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol

(4S,5S)-4,5-Bis(diphenylhydroxymethyl)-2,2-dimethyldioxolane, (+)-2,3-O-Isopropylidene-1,1,4,4-tetraphenyl-D-threitol, (+)-trans-α,αμ-(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol)

(4S)-α,α,α',α'-Tetraphenyl-2,2-dimethyl-1,3-dioxolane-4α,5β-dimethanol

(4S,5S)-α,α,α',α'-Tetraphenyl-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol

2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-4α,5β-dimethanol

α,α,α',α'-Tetraphenyl-2,2-dimethyl-1,3-dioxolane-4α,5β-bismethanol

2,2-Dimethyl-1,3-dioxolane-4,5-bis(α,α-diphenylmethanol)

α,α'-(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(α-phenylbenzyl alcohol)

α,α,α',α'-Tetraphenyl-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol

((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol)

(+)-trans-alpha,alpha'-(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol) (2S,3S)-2,3-O-Isopropylidene-1,1,4,4-tetraphenyl-1,2,3,4-butanetetrol (+)-2,3-O-Isopropylidene-1,1,4,4-tetraphenyl-D-threitol

(+)-4,5-Bis[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolane,97%

(4S,5S)-2,2-Dimethyl-α,α,α′,α′-tetraphenyldioxolane-4,5-dimethanol ,98%

(4S,5S)-2,2-Dimethyl-α,α,α',α'-tetra(1-naphthyl)-1,3-dioxolane-4,5-dimethanol

(S,S)-taddol

(4S,5S)-2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-4,5-dimethanol, 98% (99% ee)

97.0%(LC)

(4S,5S)-2,2-Dimethyl-α

'-tetraphenyl-1,3-dioxolane-4,5-dimethanol, 98% (99% ee)

Neu5GcAc[1Me,4789Ac]α(2-6)Gal[24Bz,3Bn]-β-MP&gt

Methyl2,3,4,6-Tetra-O-pivaloyl-D-mannopyranoside&gt

Neu5Acα(2-6)Galβ(1-3)GlcNAc-β-pNP&gt

meso-2,3-Diphenylsuccinonitrile&gt

Gal[2346Ac]β(1-3)GlcNPhth[46Bzd]-β-MP&gt

(+)-4,5-Bis[hydroxy(diphenyL

1,3-Dioxolane-4,5-dimethanol, 2,2-dimethyl-α4,α4,α5,α5-tetraphenyl-, (4S,5S)-

(-)-2,3-O-isopropylidene-1,1,4,4-tetra-phenyl-D-threitol

(4S,5S)-2,2-Dimethyl-α,α,α′,α′-tetraphenyldioxolane-4,5-dimethanol

(4S,5S)-2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-4,5-dimethanol