ChemicalBook > CAS DataBase List > 4-Methylphenylsulfonylurea

4-Methylphenylsulfonylurea

Product Name
4-Methylphenylsulfonylurea
CAS No.
1694-06-0
Chemical Name
4-Methylphenylsulfonylurea
Synonyms
P-TOLUENESULFONYLUREA;4-TOLUENESULFONYLUREA;N-(Aminocarbonyl)-4-methylbenzensulfona-mide;p-Tolysulfonylurea;4-tolylsulfonylurea;P-TOLYLSULFONYLUREA;P-TOLYLSULFONGLUREA;4-Methylphenylsulfo;4-TOLUENSULFONYLUREA;Toluenesulphonylurea
CBNumber
CB6153274
Molecular Formula
C8H10N2O3S
Formula Weight
214.24
MOL File
1694-06-0.mol
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4-Methylphenylsulfonylurea Property

Melting point:
196-198 °C
Density 
1.3844 (rough estimate)
refractive index 
1.5690 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
5.07±0.10(Predicted)
form 
Solid
color 
White to Off-White
Water Solubility 
777.9mg/L(37 ºC)
InChI
InChI=1S/C8H10N2O3S/c1-6-2-4-7(5-3-6)14(12,13)10-8(9)11/h2-5H,1H3,(H3,9,10,11)
InChIKey
RUTYWCZSEBLPAK-UHFFFAOYSA-N
SMILES
C1(S(NC(N)=O)(=O)=O)=CC=C(C)C=C1
CAS DataBase Reference
1694-06-0(CAS DataBase Reference)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
45-36/37/39-26
HS Code 
2935.90.9500
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H304May be fatal if swallowed and enters airways

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P331Do NOT induce vomiting.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS003387
Product name
4-toluenesulfonylurea
Purity
Aldrich<SUP>CPR</SUP>
Packaging
500 mg
Price
$73.1
Updated
2025/07/31
TCI Chemical
Product number
T2890
Product name
p-Toluenesulfonylurea
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$130
Updated
2025/07/31
TRC
Product number
T536040
Product name
N-(p-Toluenesulfonyl)urea
Packaging
50g
Price
$460
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
APN0000422
Product name
P-TOLYLSULFONGLUREA
Purity
95.00%
Packaging
25G
Price
$584.85
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
72691
Product name
N-(p-Toluenesulfonyl)urea
Packaging
5G
Price
$610
Updated
2021/12/16
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4-Methylphenylsulfonylurea Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

N-(p-Toluenesulfonyl)urea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.

Uses

4-Methylphenylsulfonylurea can be used as pharmaceutical intermediate.

Uses

4-Methylphenylsulfonylurea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.

4-Methylphenylsulfonylurea Preparation Products And Raw materials

Raw materials

Tosyl chloride p-Toluenesulfonamide

Preparation Products

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4-Methylphenylsulfonylurea Suppliers

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View Lastest Price from 4-Methylphenylsulfonylurea manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
4-Methylphenylsulfonylurea 1694-06-0
Price
US $100.00-45.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-07
Shouguang Nuomeng Chemical Co Ltd.
Product
p-Toluenesulfonylurea,4-toluenesulfonylurea,PTSU 1694-06-0
Price
US $0.00/KG
Min. Order
1KG
Purity
≥98.0%
Supply Ability
500tons
Release date
2025-01-24
Hebei Chuanghai Biotechnology Co,.LTD
Product
4-Methylphenylsulfonylurea 1694-06-0
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-19

1694-06-0, 4-MethylphenylsulfonylureaRelated Search:

Tosyl cyanide 4-Methylbenzenesulfonhydrazide Tosylmethyl isocyanide Tosyl chloride Toluenesulfonamide 4-Hydroxytolbutamide Tosyl azide TOLBUTAMIDE p-Toluenesulfonamide Glibenclamide TOLAZAMIDE Glipizide ACETOHEXAMIDE Gliclazide Tolpentamide 4-Methylphenylsulfonylurea 4-Carboxytolbutamide Methyl Ester 4-(4-METHYLPHENYLSULFONYL)SEMICARBAZIDE HYDROCHLORIDE

  • 4-tolylsulfonylurea
  • N-(p-Toluenesulfonyl)urea
  • BenzenesulfonaMide,N-(aMinocarbonyl)-4-Methyl-
  • 4-TOLUENSULFONYLUREA
  • Para-Toluene Sulfonyl Urea
  • Tolbutamide EP Impurity B
  • Gliclazide Impurity 12
  • N-(Aminocarbonyl)-4-methylbenzensulfona-mide
  • p-Tolysulfonylurea
  • P-TOLUENESULFONYLUREA
  • P-TOLUENESULPHONYLUREA
  • P-TOLYLSULFONYLUREA
  • P-TOLYLSULFONGLUREA
  • p-Tolune sulfonyl carbamide
  • P-TOLUENE SULFONYCARBAMIDE
  • N-(4-Toluenesulfonyl)-urea
  • P-TOLYLSULFONYLCARBAMIDE
  • N-(p-Methylphenylsulfonyl)urea
  • N-(p-Tolylsulfonyl)urea
  • p-Toluenesulfonylurea,98%
  • p-Toluenesulfonylurea4-Methylphenylsulfonylurea
  • 4-Methylphenylsulfo
  • 4-METHYLPHENYLSULFONYLURE...
  • Paratoluenesulfonylurea (PTSU)
  • p-Toluenesulfonylurea (PTSU)
  • N-CarbaMoyl-4-MethylbenzenesulfonaMide
  • [(4-Methylbenzene)sulfonyl]urea
  • 4-toluenesulphonyl urea
  • N-(aminocarbonyl)-4-methylbenzenesulphonamide
  • para-Toluenesulphonyl urea
  • 4-TOLUENESULFONYLUREA
  • 4-METHYLPHENYLSULFONYLUREA
  • Tolbutamide Impurity 2 (Tolbutamide EP Impurity B)
  • Toluenesulphonylurea
  • 1-[(4-methylphenyl)sulfonyl]urea (toluenesulfonylurea)
  • p-Toluenesulfonylurea,4-toluenesulfonylurea,PTSU
  • 1694-06-0
  • 1674-06-0
  • C8H10N2O3S
  • chemical additive
  • pharmaceutical intermediate