2'-HYDROXY-4',5'-DIMETHOXYACETOPHENONE

Product Name: 2'-HYDROXY-4',5'-DIMETHOXYACETOPHENONE
CAS No.: 20628-06-2
Chemical Name: 2'-HYDROXY-4',5'-DIMETHOXYACETOPHENONE
Synonyms: AURORA KA-3659;4,5-DIMETHOXY-2-HYDROXYACETOPHENONE;4',5'-DIMETHOXY-2'-HYDROXYACETOPHENONE;2'-HYDROXY-4',5'-DIMETHOXYACETOPHENONE;4',5'-Dimethoxyt-2'-hydroxyacetophenone;2'-Hydroxy-4',5'-dimethoxyacetophenone>4',5'- Dimethoxyt -2'- hydroxy acetophenone;Ethanone, 1-(2-hydroxy-4,5-dimethoxyphenyl)-;1-(2-HYDROXY-4,5-DIMETHOXYPHENYL)ETHAN-1-ONE
CBNumber: CB6153764
Molecular Formula: C10H12O4
Formula Weight: 196.2
MOL File: 20628-06-2.mol

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2'-HYDROXY-4',5'-DIMETHOXYACETOPHENONE Property

Melting point:: 113-114°C
Boiling point:: 332.3±37.0 °C(Predicted)
Density: 1.172±0.06 g/cm3(Predicted)
storage temp.: RT, stored under nitrogen
pka: 10.29±0.23(Predicted)
form: powder
color: White to Light yellow to Light orange
InChI: 1S/C10H12O4/c1-6(11)7-4-9(13-2)10(14-3)5-8(7)12/h4-5,12H,1-3H3
InChIKey: KEQHBVWVKYHDCS-UHFFFAOYSA-N
SMILES: COc1cc(O)c(cc1OC)C(C)=O
CAS DataBase Reference: 20628-06-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 2914500090
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H9904
Product name: 2′-Hydroxy-4′,5′-dimethoxyacetophenone
Packaging: 5g
Price: $330
Updated: 2023/06/20

TCI Chemical

Product number: H1206
Product name: 2'-Hydroxy-4',5'-dimethoxyacetophenone
Purity: >98.0%(GC)
Packaging: 5g
Price: $162
Updated: 2025/07/31

TRC

Product number: H972793
Product name: 1-(2-Hydroxy-4,5-dimethoxyphenyl)ethanone
Packaging: 500mg
Price: $60
Updated: 2021/12/16

TRC

Product number: H972793
Product name: 1-(2-Hydroxy-4,5-dimethoxyphenyl)ethanone
Packaging: 1g
Price: $105
Updated: 2021/12/16

TRC

Product number: H972793
Product name: 1-(2-Hydroxy-4,5-dimethoxyphenyl)ethanone
Packaging: 2.5g
Price: $220
Updated: 2021/12/16

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2'-HYDROXY-4',5'-DIMETHOXYACETOPHENONE Chemical Properties,Usage,Production

Uses

1-(2-Hydroxy-4,5-dimethoxyphenyl)ethanone is a useful reagent in Vilsmeier-Haack reaction.

Preparation

Preparation by partial methylation of 2,5-dihydroxy-4-methoxyacetophenone, ? with methyl iodide in the presence of potassium carbonate in refluxing acetone (81%) ; ? with dimethyl sulfate in the presence of potassium carbonate in refluxing acetone (71%), in the presence of sodium methoxide in methanol (byproduct) or in the presence of sodium hydroxide in boiling aqueous ethanol (37%) ; ? with an excess of ethereal diazomethane in methanol (93%).

2'-HYDROXY-4',5'-DIMETHOXYACETOPHENONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-HYDROXY-4',5'-DIMETHOXYACETOPHENONE Suppliers

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20628-06-2, 2'-HYDROXY-4',5'-DIMETHOXYACETOPHENONERelated Search:

3'-BENZYLOXY-4',5,6,7-TETRAMETHOXYFLAVONE EUPATORIN-5-METHYL ETHER 3',4',5',5,6,7-HEXAMETHOXYFLAVONE 2'-HYDROXY-4',5'-DIMETHOXYACETOPHENONE 3',4',5',6,7,8-HEXAMETHOXY-5-HYDROXYFLAVONE 4',6,7-Trimethoxyisoflavone 3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE 2,4,5-TRIETHOXYBENZOPHENONE 5,6,7-TRIMETHOXYFLAVONE SCUTELLAREIN TETRAMETHYL ETHER 4-HYDROXY-3,5-DIMETHOXYACETOPHENONE,4'-HYDROXY-3',5'-DIMETHOXYACETOPHENONE Rubone~2,4,5-Trimethoxybenzylidene(2-hydroxy-4,6-dimethoxyacetophenone),2,4,5-Trimethoxybenzylidene(2-hydroxy-4,6-dimethoxyacetophenone) 2-HYDROXY-4,6-DIMETHOXYACETOPHENONE,2'-HYDROXY-4',6'-DIMETHOXYACETOPHENONE,6-HYDROXY-2,4-DIMETHOXYACETOPHENONE Tangeretin MELICOPIDINE 2',4',5'-TRIMETHOXYACETOPHENONE 6,7-DIMETHOXY-2,2-DIMETHYL-4-CHLOROMANONE 2,3,4-TRIMETHOXY-6-HYDROXYACETOPHENONE

AURORA KA-3659

4',5'-DIMETHOXY-2'-HYDROXYACETOPHENONE

4,5-DIMETHOXY-2-HYDROXYACETOPHENONE

1-(2-HYDROXY-4,5-DIMETHOXYPHENYL)ETHAN-1-ONE

2'-HYDROXY-4',5'-DIMETHOXYACETOPHENONE

2'-Hydroxy-4',5'-dimethoxyacetophenone&gt

Ethanone, 1-(2-hydroxy-4,5-dimethoxyphenyl)-

4',5'- Dimethoxyt -2'- hydroxy acetophenone

4',5'-Dimethoxyt-2'-hydroxyacetophenone

20628-06-2

C10

Building Blocks

Organic Building Blocks

Ketones

Carbonyl Compounds

Aromatic Acetophenones & Derivatives (substituted)