ChemicalBook > CAS DataBase List > GYPENOSIDE-XVII

GYPENOSIDE-XVII

Product Name
GYPENOSIDE-XVII
CAS No.
80321-69-3
Chemical Name
GYPENOSIDE-XVII
Synonyms
GP-17;Gynosaponin S;Gypenoside ⅩⅦ;GYPENOSIDE-XVII;Gypenoside XVII-RM;Gypenoside XVII (Gynosaponin S);3β-(β-D-Glucopyranosyloxy)-12β-hydroxy-5α-dammar-24-en-20-yl 6-O-β-D-glucopyranosyl-β-D-glucopyranoside;β-D-Glucopyranoside, (3β,12β)-3-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-20-yl 6-O-β-D-glucopyranosyl-;(3beta,12beta)-3-(beta-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-20-yl 6-O-beta-D-glucopyranosyl-beta-D-glucopyranoside;(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(2S)-2-[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2-yl]oxyoxan-2-yl]methoxy]oxane-3,4,5-triol
CBNumber
CB61553295
Molecular Formula
C48H82O18
Formula Weight
947.15
MOL File
80321-69-3.mol
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GYPENOSIDE-XVII Property

Melting point:
>183°C (dec.)
Boiling point:
1013.5±65.0 °C(Predicted)
Density 
1.38
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
form 
Solid
pka
12.90±0.70(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
InChIKey
ZRBFCAALKKNCJG-LBKPMPSYNA-N
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
G931815
Product name
GypenosideXVII
Packaging
5mg
Price
$180
Updated
2021/12/16
Usbiological
Product number
297102
Product name
Gypenoside XVII
Packaging
5mg
Price
$359
Updated
2021/12/16
Usbiological
Product number
300394
Product name
Gypenoside XVII
Packaging
20mg
Price
$490
Updated
2021/12/16
Biosynth Carbosynth
Product number
OG32258
Product name
Gypenoside XVII
Packaging
5mg
Price
$75
Updated
2021/12/16
ChemScene
Product number
CS-4163
Product name
GypenosideXVII
Purity
99.63%
Packaging
5mg
Price
$120
Updated
2021/12/16
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GYPENOSIDE-XVII Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Fiveleaf Gynostemma Herb.

Uses

Gypenoside XVII is a major saponin abundant in ginseng and Panax notoginseng which ameliorated amyloid-(Aβ)25-35-induced apoptosis in PC12 cells by regulating autophagy.

Definition

ChEBI: Gypenoside XVII is a ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranoside and beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It has a role as a plant metabolite. It is a 12beta-hydroxy steroid, a beta-D-glucoside, a disaccharide derivative, a ginsenoside and a tetracyclic triterpenoid. It derives from a hydride of a dammarane.

in vivo

Body weights are measured as physical measures of hormone bioactivity. Mean body weights are significantly higher in every group compared to that of the control, but there is no significant difference in body weight between the different treatments during the 10-week feeding. The mouse plasma lipid levels are also measured at the end of 10 weeks of a high-fat diet. Circulating levels of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) are significantly increased in the treated groups of ApoE-/- mice compared with those of the C57BL/6J control group; Gypenoside XVII (GP-17) and Probucol treatment substantially decreases both of these parameters relative to those of the ApoE-/- model group[1].

GYPENOSIDE-XVII Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from GYPENOSIDE-XVII manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Gypenoside XVII 80321-69-3
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-11-11
Career Henan Chemical Co
Product
GYPENOSIDE-XVII 80321-69-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
25kg
Release date
2019-07-12

80321-69-3, GYPENOSIDE-XVIIRelated Search:


  • GYPENOSIDE-XVII
  • GP-17
  • 3β-(β-D-Glucopyranosyloxy)-12β-hydroxy-5α-dammar-24-en-20-yl 6-O-β-D-glucopyranosyl-β-D-glucopyranoside
  • Gypenoside ⅩⅦ
  • (3beta,12beta)-3-(beta-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-20-yl 6-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
  • Gynosaponin S
  • Gypenoside XVII (Gynosaponin S)
  • β-D-Glucopyranoside, (3β,12β)-3-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-20-yl 6-O-β-D-glucopyranosyl-
  • (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(2S)-2-[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2-yl]oxyoxan-2-yl]methoxy]oxane-3,4,5-triol
  • Gypenoside XVII-RM
  • 80321-69-3
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract