5-Bromo-1,3-difluoro-2-nitrobenzene
- Product Name
- 5-Bromo-1,3-difluoro-2-nitrobenzene
- CAS No.
- 147808-42-2
- Chemical Name
- 5-Bromo-1,3-difluoro-2-nitrobenzene
- Synonyms
- Vandetanib Impurity 12;4-BroMo-2,6-difluoronitrobenzene;1-Bromo-3,5-difluoro-4-nitrobenzene;5-bromo-1,3-difluoro-2-nitrobenzene;3,5-Difluoro-4-nitrobromobenzene 98%;Benzene, 5-bromo-1,3-difluoro-2-nitro-;5-Bromo-1,3-difluoro-2-nitrobenzene, 4-Bromo-2,6-difluoronitrobenzene
- CBNumber
- CB61563485
- Molecular Formula
- C6H2BrF2NO2
- Formula Weight
- 237.99
- MOL File
- 147808-42-2.mol
5-Bromo-1,3-difluoro-2-nitrobenzene Property
- Boiling point:
- 266 °C
- Density
- 1.890
- Flash point:
- 114 °C
- storage temp.
- 2-8°C
- form
- powder
- color
- Faint yellow to orange
Safety
- HS Code
- 2904990090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- B690333
- Product name
- 5-Bromo-1,3-difluoro-2-nitrobenzene
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 4654-9-X1
- Product name
- 3,5-Difluoro-4-nitrobromobenzene
- Packaging
- 5G
- Price
- $56
- Updated
- 2021/12/16
- Product number
- CS-W009157
- Product name
- 5-Bromo-1,3-difluoro-2-nitrobenzene
- Purity
- 99.94%
- Packaging
- 10g
- Price
- $72
- Updated
- 2021/12/16
- Product number
- PC57010
- Product name
- 3,5-Difluoro-4-nitrobromobenzene
- Purity
- 98%
- Packaging
- 10g
- Price
- $74
- Updated
- 2021/12/16
- Product number
- J94539
- Product name
- 5-Bromo-1,3-difluoro-2-nitrobenzene
- Packaging
- 10g
- Price
- $85
- Updated
- 2021/12/16
5-Bromo-1,3-difluoro-2-nitrobenzene Chemical Properties,Usage,Production
Synthesis
Sodium perborate tetrahydrate (18.5 g, 0.12 mol, 5.0 eq) was suspended in glacial acetic acid (125 mL) and heated to 65 °C. 4-Bromo-2,6-difluoroanilline(5.0 g, 24.0 mmol, 1.0 eq) dissolved in glacial acetic acid (50 mL) was added slowly through a funnel over 4 h. After the addition, the reaction mixture was heated for 3 h additional hours before a second portion of NaBO3·4H2O (6.0 g, 30.0 mmol) was added. Then, the mixture was stirred for 14 h, and a third portion of oxidating agent (9.0 g, 45.0 mmol) was added. 9 h after the third addition full consumption of the starting material was indicated by TLC. After cooling the mixture to room temperature, the formed solid was removed by filtration. The filtrate was poured into ice-cold water (300 mL). The precipitated solid was filtered off and dried to give the product 5-Bromo-1,3-difluoro-2-nitrobenzene as a yellow solid (3.40 g 60percent).
5-Bromo-1,3-difluoro-2-nitrobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
5-Bromo-1,3-difluoro-2-nitrobenzene Suppliers
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
View Lastest Price from 5-Bromo-1,3-difluoro-2-nitrobenzene manufacturers
- Product
- 5-Bromo-1,3-difluoro-2-nitrobenzene 147808-42-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-19
- Product
- 5-Bromo-1,3-difluoro-2-nitrobenzene 147808-42-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 96%-98%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-18