4-Fluoronitrobenzene

Uses

Product Name: 4-Fluoronitrobenzene
CAS No.: 350-46-9
Chemical Name: 4-Fluoronitrobenzene
Synonyms: 1-FLUORO-4-NITROBENZENE;P-FLUORONITROBENZENE;4-NITROFLUOROBENZENE;NSC 10281;4-Fluornitrobenzol;Fluoro-4-nitrobenz;Fluoronitrobenzene3;P-NITROFLUOROBENZENE;4-Fluoronitrobenzene;p-fluoromitrobenzene
CBNumber: CB1711989
Molecular Formula: C6H4FNO2
Formula Weight: 141.1
MOL File: 350-46-9.mol

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4-Fluoronitrobenzene Property

Melting point:: 21 °C (lit.)
Boiling point:: 205 °C (lit.)
Density: 1.33 g/mL at 25 °C (lit.)
vapor density: >1 (vs air)
vapor pressure: 5.5 mm Hg ( 70 °C)
refractive index: n20/D 1.531(lit.)
Flash point:: 182 °F
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Liquid After Melting
Specific Gravity: 1.330
color: deep greenish-yellow
Water Solubility: Insoluble in water.
BRN: 606923
Stability:: Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey: WFQDTOYDVUWQMS-UHFFFAOYSA-N
LogP: 1.8 at 20℃
CAS DataBase Reference: 350-46-9(CAS DataBase Reference)
NIST Chemistry Reference: Benzene, 1-fluoro-4-nitro-(350-46-9)
EPA Substance Registry System: p-Fluoronitrobenzene (350-46-9)

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Safety

Hazard Codes: Xn,T,Xi
Risk Statements: 20/21/22-33
Safety Statements: 36-36/37
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 1
RTECS: DA1400000
Hazard Note: Toxic/Irritant
TSCA: TSCA listed
HazardClass: 6.1
PackingGroup: III
HS Code: 29049085
Hazardous Substances Data: 350-46-9(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H331Toxic if inhaled

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: F11204
Product name: 1-Fluoro-4-nitrobenzene
Purity: 99%
Packaging: 5g
Price: $39.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: F11204
Product name: 1-Fluoro-4-nitrobenzene
Purity: 99%
Packaging: 100g
Price: $64.3
Updated: 2025/07/31

TCI Chemical

Product number: F0105
Product name: 4-Fluoronitrobenzene
Purity: >98.0%(GC)
Packaging: 25g
Price: $27
Updated: 2025/07/31

TCI Chemical

Product number: F0105
Product name: 4-Fluoronitrobenzene
Purity: >98.0%(GC)
Packaging: 100g
Price: $51
Updated: 2025/07/31

Sigma-Aldrich

Product number: F11204
Product name: 1-Fluoro-4-nitrobenzene
Purity: 99%
Packaging: 500g
Price: $210
Updated: 2025/07/31

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4-Fluoronitrobenzene Chemical Properties,Usage,Production

Uses

4-Nitrofluorobenzene, is an aryl fluorinated building block, and a common intermediate used for the synthesis of many industrial useful compounds. It is used for the preparation of novel soluble aromatic polyimides, such as 1,3,5-Tris(4-aminophenoxy)benzene (TAB).

Chemical Properties

yellow liquid

Uses

1-Fluoro-4-nitrobenzene used as a component of hair dyes, as pharmaceutical intermediates. It is also used for the preparation of novel soluble aromatic polyimides

Synthesis Reference(s)

Journal of the American Chemical Society, 78, p. 6034, 1956 DOI: 10.1021/ja01604a022
Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8
Tetrahedron Letters, 30, p. 7199, 1989 DOI: 10.1016/S0040-4039(01)93933-4

Flammability and Explosibility

Non flammable

Synthesis

Synthesis of 4-fluoronitrobenzene. Reagents and conditions: (a) PCl5 (1.1 equiv.), PhPOCl2 (0.11 equiv.), 160°C, 8 h (<65%); (b) KF (1.5 equiv.), bis(phosphoranylidene)ammonium chloride (0.04 equiv.), DMSO, 150°C, 8 h (51%).

Purification Methods

Crystallise it from EtOH. [Beilstein 5 H 241, 5 IV 719.]

4-Fluoronitrobenzene Preparation Products And Raw materials

Raw materials

4-Chloronitrobenzene Fluorobenzene

Preparation Products

4-Morpholinoaniline 4-(4-AMINOPHENYL)MORPHOLIN-3-ONE 4-(1H-PYRAZOL-1-YL)PHENYL ISOTHIOCYANATE 4-Fluoroaniline Pioglitazone 3-Chloro-4-fluoronitrobenzene

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4-Fluoronitrobenzene Suppliers

Americas 1 Belgium 2 China 486 Europe 4 France 2 Germany 5 India 45 Indonesia 1 Italy 1 Japan 5 Slovakia 1 South Africa 1 South Korea 1 Switzerland 3 The Netherlands 2 Ukraine 2 United Kingdom 16 United States 51 Global 629

Qi-Chem Co., Ltd.

Tel: 0411-88165951 13601035838
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Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.

Tel: 13396369453 QQ3007939906 18678026865
Fax: 0536-2101172
Email: sdfantai@163.com
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Weifang Siyuan Chemical Co., Ltd.

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Shandong Xibang Biological Technology Development Co. LTD

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Xi'an Beckman Chemical Technology Co., Ltd.

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J & K SCIENTIFIC LTD.

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Meryer (Shanghai) Chemical Technology Co., Ltd.

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INTATRADE GmbH

Tel: +49 3493/605464
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Email: sales@intatrade.de
Country: Germany
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3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
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ProdList: 15838
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View Lastest Price from 4-Fluoronitrobenzene manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4-Fluoronitrobenzene 350-46-9
Price: US $0.00/KG
Min. Order: 25KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-23

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Fluoronitrobenzene 350-46-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-18

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 4-Fluoronitrobenzene 350-46-9
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-11-29

350-46-9, 4-FluoronitrobenzeneRelated Search:

4-Nitrobenzoic acid 4-Nitrophenyl phosphate bis(cyclohexylammonium) salt 3-(4-Nitrophenyl)-beta-alanine 4-Nitrobenzaldehyde 4-Fluorothiophenol 4-Fluorobenzaldehyde 4-Fluorophenoxyacetic acid Methyl 4-fluorobenzoate Ethyl 4-fluorobenzoate 4-Fluorobenzoic acid 4-Fluorobenzonitrile 4-Fluorobenzyl chloride 4-Fluorophenylacetic acid 4-Bromofluorobenzene 3,4-Difluoronitrobenzene Nitrobenzene 4-Bromo-1-fluoro-2-nitrobenzene 1,2,3-Trifluoro-4-nitrobenzene

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P-FLUORONITROBENZENE

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p-fluoromitrobenzene

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4-NITROFLUOROBENZENE

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Valsartan Impurity 74

4-Fluoronitrobenzene&gt

4-Fluoronitrobenzene, 99%, for synthesis

4-Fluoronitrobenzene,>98%

4-Fluoronitrobenzene ISO 9001：2015 REACH

4-FLUORONITROBENZENE / 1-FLUORO-4-NITROBENZENE

42-Flouromitrobrnzene

4-Fluoronitrobenzene 350-46-9 99.%

1-Fluoro-4-Nitrobenzene extrapure, 99%

Para Fluoro Nitro Benzene (PFNB)

4-Fluoro-4-nitrobenzene

1-Fluoro-4-nitrobenzene, 98%

350-46-9

350-64-9

Building Blocks

Nitro Compounds

Nitrogen Compounds

Organic Building Blocks

Phenyls & Phenyl-Het

Nitro Compounds

Nitrogen Compounds

Organic Building Blocks

Aromatic Halides (substituted)

Halides

Phenyls & Phenyl-Het