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2-Bromo-4-(trifluoromethyl)aniline

Product Name
2-Bromo-4-(trifluoromethyl)aniline
CAS No.
57946-63-1
Chemical Name
2-Bromo-4-(trifluoromethyl)aniline
Synonyms
BUTTPARK 44\03-51;TIMTEC-BB SBB000789;4-Amino-3-bromobenzo;4-AMINO-3-BROMOBENZOTRIFLUORIDE;3-BROMO-4-AMINO BENZOTRIFLUORIDE;2-Bromo-4-(trifuoromethyl)aniline;4-Amino-3-bromobenzotrifluoride98%;4-(Trifluoromethyl)-2-bromoaniline;2-Bromo-4-(trifluoromethyl)aniline;4-Amino-3-bromobenzotrifluoride 98%
CBNumber
CB6156381
Molecular Formula
C7H5BrF3N
Formula Weight
240.02
MOL File
57946-63-1.mol
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2-Bromo-4-(trifluoromethyl)aniline Property

Melting point:
26-28°C
Boiling point:
109-110 °C10 mm Hg(lit.)
Density 
1,7 g/cm3
refractive index 
n20/D 1.524(lit.)
Flash point:
110 °C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Crystals
pka
0.70±0.10(Predicted)
color 
White
BRN 
8139978
InChI
InChI=1S/C7H5BrF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2
InChIKey
QKRJIXSZTKOFTD-UHFFFAOYSA-N
SMILES
C1(N)=CC=C(C(F)(F)F)C=C1Br
CAS DataBase Reference
57946-63-1(CAS DataBase Reference)
NIST Chemistry Reference
Benzenamine, 2-bromo-4-(trifluoromethyl)-(57946-63-1)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-36-36/37/39
RIDADR 
2810
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
6.1
HS Code 
29214990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H311Toxic in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309IF exposed or if you feel unwell:

P310Immediately call a POISON CENTER or doctor/physician.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
518700
Product name
2-Bromo-4-(trifluoromethyl)aniline
Purity
97%
Packaging
1g
Price
$34.2
Updated
2022/05/15
TCI Chemical
Product number
A1578
Product name
4-Amino-3-bromobenzotrifluoride
Purity
>98.0%(GC)
Packaging
1g
Price
$28
Updated
2025/07/31
TCI Chemical
Product number
A1578
Product name
4-Amino-3-bromobenzotrifluoride
Purity
>98.0%(GC)
Packaging
5g
Price
$99
Updated
2025/07/31
TRC
Product number
A602503
Product name
4-Amino-3-bromobenzotrifluoride
Packaging
10mg
Price
$45
Updated
2021/12/16
Oakwood
Product number
003957
Product name
4-Amino-3-bromobenzotrifluoride
Purity
95%
Packaging
5g
Price
$10
Updated
2021/12/16
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2-Bromo-4-(trifluoromethyl)aniline Chemical Properties,Usage,Production

Chemical Properties

white crystals

Uses

2-Bromo-4-(trifluoromethyl)aniline is mainly used as a raw material for organic synthesis or a reagent for chemical reactions, and can be used to prepare 2-Amino-5-trifluoromethylbenzonitrile and 2-Bromo-1-nitro-4-(trifluoromethyl) benzene among other organic heterocyclic compounds.

Synthesis

2-Bromo-4-(trifluoromethyl)aniline is prepared by reacting 4-(trifluoromethyl)aniline with N-bromosuccinimide in dichloromethane. The following is the reaction procedure:
Add 200 mL of distilled CH2Cl 2 and 4- (trifluoromethyl) aniline (20 g, 124.13 mmol) to a two neck flask. Slowly dropwise N-bromosuccinimide (24.3 g, 136.5 mmol) dissolved in CH2Cl2. When the reaction is complete, extract with CH2Cl2. Purification by column separation (EA: Hx = 1: 4) (yield: 50percent)

References

[1] Journal of Organic Chemistry, 2018, vol. 83, # 2, p. 930 - 938
[2] Patent: KR2018/50795, 2018, A. Location in patent: Paragraph 0086; 0087; 0104-0106
[3] Patent: US3946025, 1976, A
[4] Chinese Journal of Chemistry, 2018, vol. 36, # 9, p. 815 - 818
[5] Patent: US3995042, 1976, A

2-Bromo-4-(trifluoromethyl)aniline Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Bromo-4-(trifluoromethyl)aniline Suppliers

Americas 1 Belgium 2 China 190 Europe 3 France 1 Germany 3 India 11 Italy 1 Japan 3 Switzerland 2 Ukraine 2 United Kingdom 21 United States 38 Global 278
Shanghai ZhengXia Medical Technology Co., Ltd.
Tel
13585673075
Email
317388297@qq.com
Country
China
ProdList
254
Advantage
50
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
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66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
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View Lastest Price from 2-Bromo-4-(trifluoromethyl)aniline manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4-Amino-3-bromobenzotrifluoride 57946-63-1
Price
US $0.00-0.00/KG
Min. Order
50mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-08
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Amino-3-bromobenzotrifluoride 57946-63-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Amino-3-bromobenzotrifluoride 57946-63-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

57946-63-1, 2-Bromo-4-(trifluoromethyl)anilineRelated Search:

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  • C7
  • Amines
  • Building Blocks
  • Nitrogen Compounds
  • Organic Building Blocks
  • Amines
  • C7
  • Nitrogen Compounds
  • Aniline
  • Benzotrifluoride Series
  • Aromatic Halides (substituted)