ChemicalBook > CAS DataBase List > 4-Bromopyrazole

4-Bromopyrazole

Product Name
4-Bromopyrazole
CAS No.
2075-45-8
Chemical Name
4-Bromopyrazole
Synonyms
4-BROMO-1H-PYRAZOLE;DK660;93℃-96℃;NSC 522023;AKOS B001462;WLN: T5MNJ DE;4-Brompyrazole;4-BROMOPYRAZOLE;4-bromo-pyrazol;Baricitinib-001
CBNumber
CB6158239
Molecular Formula
C3H3BrN2
Formula Weight
146.97
MOL File
2075-45-8.mol
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4-Bromopyrazole Property

Melting point:
93-96 °C (lit.)
Boiling point:
250-260 °C (lit.)
Density 
1.5979 (rough estimate)
refractive index 
1.5260 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform, DMSO, Methanol
form 
Crystalline Powder
pka
12.71±0.50(Predicted)
color 
White to cream
Water Solubility 
Slightly soluble in water.
InChI
InChI=1S/C3H3BrN2/c4-3-1-5-6-2-3/h1-2H,(H,5,6)
InChIKey
FHZALEJIENDROK-UHFFFAOYSA-N
SMILES
N1C=C(Br)C=N1
CAS DataBase Reference
2075-45-8(CAS DataBase Reference)
NIST Chemistry Reference
1H-pyrazole, 4-bromo-(2075-45-8)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
RTECS 
UQ6200000
HazardClass 
IRRITANT
HS Code 
29331990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
374822
Product name
4-Bromopyrazole
Purity
99%
Packaging
1g
Price
$10.4
Updated
2024/03/01
Sigma-Aldrich
Product number
374822
Product name
4-Bromopyrazole
Purity
99%
Packaging
10g
Price
$99.2
Updated
2024/03/01
TCI Chemical
Product number
B3745
Product name
4-Bromopyrazole
Purity
>98.0%(GC)
Packaging
5g
Price
$29
Updated
2024/03/01
TCI Chemical
Product number
B3745
Product name
4-Bromopyrazole
Purity
>98.0%(GC)
Packaging
25g
Price
$83
Updated
2024/03/01
Alfa Aesar
Product number
H64673
Product name
4-Bromo-1H-pyrazole, 98+%
Packaging
25g
Price
$38.65
Updated
2024/03/01
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4-Bromopyrazole Chemical Properties,Usage,Production

Chemical Properties

White to cream crystalline powder

Uses

4-Bromopyrazole can be used as starting material employed in a synthesis of 1,4′-bipyrazoles and in suzuki reaction.

Uses

As a mono substituted pyrozole, 4-Bromopyrazole can be used as Inhibitor of human liver alcohol dehydrogenase and used in mutagenicity study with the L-arabinose resistance test of Salmonella typhimurium.

General Description

4-Bromopyrazole is a pyrazole derivative. It is reported to react with titanium tetrachloride to afford binary adducts. Mutagenicity of 4-bromopyrazole has been tested using the L-arabinose forward mutation assay of Salmonella typhimurium. It is reported to inhibit the oxidative phosphorylation, the ATP-32P exchange reaction, and energy dependent and independent calcium uptake.

References

[1] Saied M. Soliman, Ahmed M.A. Badr. “Synthesis, structure and Hirshfeld analysis of the potent antimicrobial [Ag(4-bromopyrazole)2ClO4] complex.” Polyhedron 171 (2019): Pages 323-329.
[2] Shaoling Wang , Hongkun Zhao, Cunbin Du . “Solubility, solution thermodynamics and preferential solvation for 4-bromopyrazole in mixed solvents of (methanol/ethanol+ water) from T = (283.15 to 318.15) K.” Journal of Chemical Thermodynamics 112 (2017): Pages 146-154.

4-Bromopyrazole Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Bromopyrazole Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
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View Lastest Price from 4-Bromopyrazole manufacturers

Dorne Chemical Technology co. LTD
Product
4-Bromopyrazole 2075-45-8
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2024-06-25
Hubei Lidu New Material Technology Co., Ltd
Product
4-BROMOPYRAZOLE 2075-45-8
Price
US $0.00/g
Min. Order
1g
Purity
98%
Supply Ability
20tons
Release date
2024-09-18
Hebei Weibang Biotechnology Co., Ltd
Product
4-Bromopyrazole 2075-45-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-30

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