ChemicalBook > CAS DataBase List > 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Product Name
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.
61676-62-8
Chemical Name
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Synonyms
Isopropyl pinacol borate;Isopropoxyboronic acid;sopropoxyboronic acid pinacol ester;AKOS BRN-0268;-1,3,2-dioxa-boroL;Isopropoxyboronic a;Triazolam Impurity 5;Isopropoxyboronic aci;2-Isopropoxy-4,4,5,5-;Isopropylpinacolylborate
CBNumber
CB6160988
Molecular Formula
C9H19BO3
Formula Weight
186.06
MOL File
61676-62-8.mol
More
Less

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Property

Boiling point:
73 °C15 mm Hg(lit.)
Density 
0.912 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.409(lit.)
Flash point:
109 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Liquid
Specific Gravity
0.912
color 
Colorless
Water Solubility 
Soluble in water.
Sensitive 
Moisture Sensitive
BRN 
1906370
InChI
InChI=1S/C9H19BO3/c1-7(2)11-10-12-8(3,4)9(5,6)13-10/h7H,1-6H3
InChIKey
MRWWWZLJWNIEEJ-UHFFFAOYSA-N
SMILES
O1C(C)(C)C(C)(C)OB1OC(C)C
CAS DataBase Reference
61676-62-8(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
10-36/37/38
Safety Statements 
16-26-36
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
HazardClass 
3
PackingGroup 
III
HS Code 
29209090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
417149
Product name
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Purity
98%
Packaging
5ml
Price
$56.3
Updated
2025/07/31
Sigma-Aldrich
Product number
417149
Product name
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Purity
98%
Packaging
25ml
Price
$94.5
Updated
2025/07/31
TCI Chemical
Product number
I0658
Product name
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$20
Updated
2025/07/31
TCI Chemical
Product number
I0658
Product name
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$54
Updated
2025/07/31
Sigma-Aldrich
Product number
417149
Product name
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Purity
98%
Packaging
100ml
Price
$239.2
Updated
2025/07/31
More
Less

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid

Uses

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane can be used as a reagent to borylate arenes and to prepare fluorenylborolane.

It can also be used in the synthesis of following intermediates for generating conjugated copolymers:

  • 9,9-Dioctyl-2,7-bis(4,4,5,5-tetramethyl1,3,2-dioxaborolane-2-yl)dibenzosilole.
  • 3,9-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5,11-di(1-decylundecyl)indolo[3,2-b]carbazole.
  • 2,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-dioctylfluorene.
  • 2,7-Bis(4′,4′,5′,5′-tetramethyl-1′,3′,2′-dioxaborolan-2′-yl)-N-9′′-heptadecanylcarbazole.

Uses

suzuki reaction

Synthesis

76-09-5

5419-55-6

61676-62-8

Step c) Preparation of isopropyl pinacol borate: triisopropyl borate (261.0 g, 1.388 mol) and pinacol (142.5 g, 1.207 mol) were added to a 20 L four-necked flask, and the mixture was heated to about 90 °C and maintained for 12 to 16 hours. The progress of the reaction was monitored by gas chromatography (GC), and the completion of the reaction was measured by a pinacol content of less than 4.0%. Upon completion of the reaction, a distillation operation was performed to collect fractions with boiling points between 174 and 178 °C to obtain the target product isopropanol pinacol borate as a colorless oil. Yields ranged from 80-90% in six 20 L batches of the operation.GC analysis showed a product purity of 87-96%, while 1H NMR analysis indicated an extremely high product purity. [The difference between GC purity and 1H NMR purity is attributed to the instability of the product under GC conditions].

References

[1] Journal of the American Chemical Society, 2001, vol. 123, # 19, p. 4617 - 4618
[2] Organic Letters, 2012, vol. 14, # 22, p. 5644 - 5647
[3] Patent: US2013/40984, 2013, A1. Location in patent: Paragraph 0482-0483
[4] Chemische Berichte, 1989, vol. 122, p. 1777 - 1782
[5] Organic Letters, 2013, vol. 15, # 18, p. 4666 - 4669

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Suppliers

Americas 1 Australia 1 Belgium 1 China 302 China Hong Kong 1 Europe 2 France 1 Germany 6 India 8 Japan 6 Switzerland 2 United Kingdom 9 United States 39 Global 379
Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
Advantage
58
GLR Innovations
Tel
+91 9891111994
Email
info@glrgroup.in
Country
India
ProdList
4535
Advantage
58
TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
Vidgas Science & Technologies Pvt Ltd.
Tel
--
Fax
--
Email
gsreddy@vidgastech.com
Country
India
ProdList
5
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
More
Less

View Lastest Price from 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 61676-62-8
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-11-18
ROSEWA HOLDING GROUP CO.,LIMITED
Product
Isopropoxyboronic acid pinacol ester 61676-62-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100ton
Release date
2023-02-10
Henan Aochuang Chemical Co.,Ltd.
Product
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 61676-62-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-08

61676-62-8, 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneRelated Search:

Methyltrimethoxysilane Ethyl 2-(Chlorosulfonyl)acetate Pinacol ISOPROPYL LAURATE Diethoxydimethylsilane Isopropyl alcohol Methyl acrylate BUTYL OLEATE 1,4-Dioxane Bis(pinacolato)diboron Tris(trimethylsilyl)phosphate Dimethyldimethoxysilane Pentaerythritol triacrylate Methyltriethoxysilane Rosin pentaerythrityl ester Titanium tetraisopropanolate Pinacolborane Potassium chloride

  • Isopropoxyboronic acid pinacol
  • Isopropoxyboronic acid picol ester
  • Isopropoxyboronic a
  • Isopropoxyboronic aci
  • 2-ISOPROPOXY-4,4,5,5-TETRAMETHYL-1,3,2-DIOABOROLANE
  • 2-Isopropoxyboronic acid, pinacol cyclic ester
  • sopropoxyboronic acid pinacol ester
  • Isopropoxyboronic acid pinacol ester 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 2-Isopropoxy-4,4,5,5-dimethyl-1,3,2-dioxaborolane
  • AKOS BRN-0268
  • 2-ISOPROPOXY-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE
  • ISOPROPOXYBORONIC ACID, PINACOL ESTER
  • 2-ISOPROPOXY-4,4,5,5-TETRAMETHYL-1,3,2-&
  • Isopropylpinacolylborate
  • 4,4,5,5-Tetramethyl-2-propan-2-yloxy-1,3,2-dioxaborolane
  • Isopropyl pinacol borate
  • Isopropoxyboronic acid pinacol este
  • 2-isopropxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • [(Prop-2-yl)oxy]boronic acid, pinacol ester, 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 2-Isopropoxy-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane(Isopropoxyboronic acid pinacol ester)
  • Isopropyl Pinacol Borane
  • Isopropoxydioxa boralane
  • 2-Isopropoxy-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane 98%
  • 1,3,2-Dioxaborolane, 4,4,5,5-tetraMethyl-2-(1-Methylethoxy)-
  • 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane&gt
  • 2-Isopropoxy-4,4,5,5-tetramethyL
  • -1,3,2-dioxa-boroL
  • Isopropoxyboronic acid
  • Isopropoxy 4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, ≥ 98.0%
  • Triazolam Impurity 5
  • 2-Isopropoxy-4,4,5,5-
  • 4,4,5,5-tetramethyl-2-(propan-2-yloxy)-1,3,2-dioxaborolane - [I3900]
  • 61676-62-8
  • C9H19BO3
  • Boric Acid Triesters
  • Boric Acid Esters
  • B (Classes of Boron Compounds)
  • Boric Acid| Boric Acid Ester| Potassium Trifluoroborate
  • B (Classes of Boron Compounds)
  • Boric Acid Esters
  • Boric Acid Triesters
  • Boronic Acids and Derivatives
  • Organoborates
  • Organometallic Reagents
  • Organic boronic acid
  • Boronic ester
  • Organoborons