(3,4-Dichlorobenzyl)methylamine
- Product Name
- (3,4-Dichlorobenzyl)methylamine
- CAS No.
- 5635-67-6
- Chemical Name
- (3,4-Dichlorobenzyl)methylamine
- Synonyms
- 1-(3,4-Dichlorophenyl);Olanexidine Impurity 7;(3,4-DICHLOROBENZYL)METHYLAMINE;N-Methyl-3,4-dichlorobenzylamine;3,4-DICHLORO-N-METHYLBENZYLAMINE;(3,4-DICHLOROBENZYL)METHYLAMINE 95%;N-(3,4-DICHLOROBENZYL)-N-METHYLAMINE;(3,4-dichlorophenyl)-N-methylmethanamine;N-(3,4-Dichlorobenzyl)-N-methylamine ,97%;(3,4-dichlorophenyl)methyl-methylammonium
- CBNumber
- CB6162902
- Molecular Formula
- C8H9Cl2N
- Formula Weight
- 190.07
- MOL File
- 5635-67-6.mol
(3,4-Dichlorobenzyl)methylamine Property
- Boiling point:
- 146 °C(Press: 47 Torr)
- Density
- 1.226±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light
- pka
- 8.77±0.10(Predicted)
- Appearance
- Colorless to light yellow Liquid
Safety
- HS Code
- 2921490090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P233Keep container tightly closed.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304IF INHALED:
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362Take off contaminated clothing and wash before reuse.
P403Store in a well-ventilated place.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D434725
- Product name
- (3,4-Dichlorobenzyl)methylamine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- D434725
- Product name
- (3,4-Dichlorobenzyl)methylamine
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 071758
- Product name
- (3,4-Dichlorobenzyl)methylamine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $30
- Updated
- 2021/12/16
- Product number
- W7007
- Product name
- (3,4-Dichlorobenzyl)methylamine
- Packaging
- 1g
- Price
- $34
- Updated
- 2021/12/16
- Product number
- FD140547
- Product name
- 1-(3,4-Dichlorophenyl)-N-methylmethanamine
- Packaging
- 5G
- Price
- $76
- Updated
- 2021/12/16
(3,4-Dichlorobenzyl)methylamine Chemical Properties,Usage,Production
Synthesis
6287-38-3
74-89-5
5635-67-6
General procedure for the synthesis of N-(3,4-dichlorobenzyl)-N-methylamine from 3,4-dichlorobenzaldehyde and methylamine: 3,4-dichlorobenzaldehyde (600 mg, 3.43 mmol, 1.0 eq.) was mixed with methylamine (0.64 mL, 5.14 mmol, 8.03 M in ethanol, 1.5 eq.) in anhydrous 1,2-dichloroethane (12 mL) and stirred under nitrogen protection for 3 hours. Subsequently, sodium triacetoxyborohydride (1.02 g, 4.81 mmol, 1.4 eq.) was added and the reaction mixture continued to be stirred at room temperature for 18 hours. Upon completion of the reaction, the mixture was poured into 2 M aqueous sodium carbonate solution and extracted with ethyl acetate (3 x 10 mL). The organic phases were combined, dried with anhydrous magnesium sulfate and concentrated under reduced pressure. Finally, the product was purified by silica gel column chromatography with the eluent methanol:methanol:dichloromethane containing 7N ammonia (the ratio was gradually changed from 1:5:94 to 1:10:89 and finally 1:15:84) to give a light yellow oily product (455 mg, 70% yield).
References
[1] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 11, p. 3016 - 3020
[2] Journal of Medicinal Chemistry, 1981, vol. 24, # 2, p. 140 - 145
(3,4-Dichlorobenzyl)methylamine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (3,4-Dichlorobenzyl)methylamine manufacturers
- Product
- (3,4-Dichlorobenzyl)methylamine 5635-67-6
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 380
- Release date
- 2019-09-01