ChemicalBook > CAS DataBase List > Tetrakis(triphenylphosphine)palladium

Tetrakis(triphenylphosphine)palladium

Product Name
Tetrakis(triphenylphosphine)palladium
CAS No.
14221-01-3
Chemical Name
Tetrakis(triphenylphosphine)palladium
Synonyms
PD(PPH3)4;TETRAKIS(TRIPHENYLPHOSPHINE)PALLADIUM(0);etrakis(triphenylphosphine)palladiuM;TETRAKIS(TRIPHENYLPHOSPHINE)PALLADIUM(O);PALLADIUM (0) TETRAKIS(TRIPHENYLPHOSPHINE);Tetra(triphenylphosphine) palladium;Tetrakis(triphenylphosphine)palladiu;PALLADIUM-TETRAKIS(TRIPHENYLPHOSPHINE);Tetrakis(triphenylphosphine)palladium, tech;Tetrakis(triphenylphosphine)palladium(0), 99.8% (metals basis), Pd 9% min
CBNumber
CB6163934
Molecular Formula
C72H60P4Pd
Formula Weight
1155.561844
MOL File
14221-01-3.mol
More
Less

Tetrakis(triphenylphosphine)palladium Property

Melting point:
103-107 °C
vapor pressure 
0Pa at 25℃
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Fine Powder or Platelets
color 
Bright yellow to khaki
Water Solubility 
insoluble
Sensitive 
Light Sensitive/Air Sensitive
Hydrolytic Sensitivity
7: reacts slowly with moisture/water
BRN 
6704828
Stability:
Light Sensitive, Moisture Sensitive
InChIKey
NANALCPCPBPJAB-UHFFFAOYSA-N
LogP
5.69 at 20℃
CAS DataBase Reference
14221-01-3(CAS DataBase Reference)
EPA Substance Registry System
Palladium, tetrakis(triphenylphosphine)-, (T-4)- (14221-01-3)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
20/22-40-36/37/38
Safety Statements 
22-24/25-36/37-37/39-26
WGK Germany 
3
F 
8-10-23
Hazard Note 
Air sensitive/Light sensitive/Irritant
TSCA 
No
HazardClass 
MOISTURE SENSITIVE, STORED UNDER ARGON
HS Code 
28439090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.14761
Product name
Tetrakis(triphenylphosphine)-palladium(0)
Purity
for synthesis
Packaging
500mg
Price
$109
Updated
2024/03/01
Sigma-Aldrich
Product number
8.14761
Product name
Tetrakis(triphenylphosphine)-palladium(0)
Purity
for synthesis
Packaging
1g
Price
$162
Updated
2024/03/01
Sigma-Aldrich
Product number
8.14761
Product name
Tetrakis(triphenylphosphine)-palladium(0)
Purity
for synthesis
Packaging
5G
Price
$456
Updated
2024/03/01
Sigma-Aldrich
Product number
8.14761
Product name
Tetrakis(triphenylphosphine)-palladium(0)
Purity
for synthesis
Packaging
25g
Price
$1180
Updated
2024/03/01
Sigma-Aldrich
Product number
216666
Product name
Tetrakis(triphenylphosphine)palladium(0)
Purity
99%
Packaging
1g
Price
$44.5
Updated
2024/03/01
More
Less

Tetrakis(triphenylphosphine)palladium Chemical Properties,Usage,Production

Chemical Properties

yellow crystals

Uses

suzuki reaction

Uses

Pd(PPh3)4 is widely used as a catalyst for palladium-catalyzed coupling reactions. Prominent applications include the Heck reaction, Suzuki coupling, Stille coupling, Sonogashira coupling, and Negishi coupling.

Uses

A high-yielding catalyst used in coupling reactions.

Uses

Tetrakis(triphenylphosphine)palladium(0) is widely used as a catalyst for palladium-catalyzed coupling reactions.

Application

Palladium-Catalyzed Three-Component Reaction for the Synthesis of Imidazolidinones.

Once the Schlenk tube containing K2CO3 (55 mg, 0.40 mmol) is flamed, dried, and filled with argon, Tetrakis(triphenylphosphine)palladium (12 mg, 0.010 mmol), PMB-protected 2,3-allenylamine (37 mg, 0.20 mmol), iodobenzene (58 mg, 0.28 mmol), phenyl isocyanate (36 mg, 0.30 mmol), and CH3CN (4 mL) are added sequentially. The resulting solution is heated to and stirred at 70°C. When the reaction is completed as monitored by TLC, the solvent is evaporated under reduced pressure, and the residue is purified by chromatography on silica gel (petroleum ether : ethyl acetate = 7:1) to afford the corresponding imidazolidione (72 mg, Y. 96%) as an oil.

Reactions

  1. Catalyst for Suzuki coupling of chiral secondary organoboronic esters.
  2. Palladium-catalyzed SNAr reactions for the synthesis of heteroaryl ethers.
  3. Catalyst for cross-coupling of a-diazocarbonyl compouns with arylboronic acids.
  4. Diastereoselective synthesis of trans-1,2-diazetidines.
  5. Palladium-catalyzed alkynyl iminium ion cyclization.
  6. Widely used reagent in a variety of transformations including Heck arylation, enyne and diyne cycloisomerization.
  7. Catalysts for cross-coupling.

Flammability and Explosibility

Non flammable

reaction suitability

reagent type: catalyst
reaction type: Cross Couplings

Purification Methods

The palladium complex is recrystallised from EtOH. It should not be heated excessively as it dissociates to Pd(PPh3)3 and PdPh3 and then further to Pd(PPh3)2 and PPh3. It is also air sensitive as PPh3 is oxidized to PPh3O. It is stable only for short periods because on exposure to heat or air it turns from yellow to orange and dissociates in solution so the solutions should be used directly. However it can always be prepared freshly by mixing Pd(NO3)2 (2mmols) and PPh3(2mmols) in hot *C6H6 when vigorous evolution of nitric oxide occurs and a solid mass separates. This is collected and crystallised from EtOH. Its cryoscopic constant in *C6H6 (at 0.601g/20mL) corresponds to M 1156 [Malatesta & Angoletti J Chem Soc 1186 1957]. It is a useful catalyst for Suzuki coupling reactions [Trost Tetrahedron 33 2615 1977]. [Beilstein 16 IV 954.] This palladium catalyst bound to a polymer support (~0.06mmol/g) is also commercially available [cf Fenger & LeDrain Tetrahedron Lett 39 4287 1998]. [Beilstein 16 IV 954.]

Tetrakis(triphenylphosphine)palladium Preparation Products And Raw materials

Raw materials

Hydrazinium hydroxide solution Acetonitrile Ethanol tert-Butyl methyl ether Toluene Hydrazine hydrate Diethyl ether Palladium chloride Ethyl acetate Dimethyl sulfoxide Triphenylphosphine

Preparation Products

3-AMINOBIPHENYL 3-(6-FORMYL-PYRIDIN-2-YL)-BENZONITRILE 6-(3-NITROPHENYL)-2-PYRIDINECARBOXALDEHYDE 6-(4-METHYLSULFANYLPHENYL)PYRIDINE-2-CARBALDEHYDE 6-(4-METHOXYPHENYL)PYRIDINE-2-CARBALDEHYDE PLUMBAGIN 6-(THIOPHEN-3-YL)PYRIDINE-2-CARBALDEHYDE Dimidium bromide 3-AMINO-6-PHENYLPYRIDAZINE 4-PHENYLETHYNYLPHTHALIC ANHYDRIDE 2-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE 6-(4-FLUOROPHENYL)PYRIDINE-2-CARBALDEHYDE 4-(6-FORMYLPYRIDIN-2-YL)BENZONITRILE 3-(3-PYRIDINYL)BENZOIC ACID 1-(3-AMINO-PYRIDIN-2-YL)-ETHANONE 6-(2-THIENYL)-2-PYRIDINECARBOXALDEHYDE 4-Hex-1-ynylbenzaldehyde 4-BENZYLOXY-3-INDOLEACETONITRILE 6-(4-CHLOROPHENYL)PYRIDINE-2-CARBALDEHYDE 3-(4-METHYLPHENYL)BENZALDEHYDE
More
Less

Tetrakis(triphenylphosphine)palladium Suppliers

Australia 2 Belgium 5 Canada 2 China 559 Europe 2 France 3 Germany 13 India 41 Italy 2 Japan 12 Norway 1 Poland 1 Russia 1 Singapore 1 South Korea 2 Sweden 1 Switzerland 3 Ukraine 1 United Kingdom 15 United States 64 Global 731
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
18478
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
AB PharmaTech,LLC
Tel
323-480-4688
Fax
323-480-4688
Email
sales@acrospharmatech.com
Country
United States
ProdList
989
Advantage
55
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Aceschem Inc.
Tel
+1-817863-6948 +1-（817）863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19632
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
Beantown Chemical Corporation
Tel
--
Fax
--
Country
United States
ProdList
396
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
MilliporeSigma (Sigma-Aldrich Corp.)
Tel
--
Fax
--
Email
@sial.com
Country
United States
ProdList
5414
Advantage
58
SynQuest Laboratories, Inc.,
Tel
--
Fax
--
Country
United States
ProdList
2301
Advantage
58
Stanford Advanced Materials (SAM)
Tel
--
Fax
--
Email
sales@SAMaterials.com
Country
United States
ProdList
102
Advantage
58
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United States
ProdList
4583
Advantage
58
Chem-Impex International, Inc. (CII)
Tel
--
Fax
--
Email
Customer@chemimpex.com
Country
United States
ProdList
893
Advantage
58
Redox Scientific
Tel
--
Fax
--
Email
info@redoxsci.com
Country
United States
ProdList
2380
Advantage
58
Heraeus Incorporated
Tel
--
Fax
--
Email
douglas.joy@heraeus.com
Country
United States
ProdList
40
Advantage
58
Leonid Chemicals Private Limited
Tel
--
Fax
--
Email
careers@leonidchemicals.com
Country
United States
ProdList
1700
Advantage
43
Fine Chem Trading LTD
Tel
--
Fax
--
Email
chemfinder@chemfinder.co.uk
Country
United States
ProdList
1609
Advantage
64
Rare Earth Products
Tel
--
Fax
--
Email
sales@rareearthproducts.com
Country
United States
ProdList
42
Advantage
58
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
Strem Chemicals, Inc.
Tel
--
Fax
--
Email
info@strem.com
Country
United States
ProdList
4910
Advantage
86
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Rare Earth Products Inc
Tel
--
Fax
--
Email
sales@rareearthproducts.com
Country
United States
ProdList
1095
Advantage
58
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Synthonix
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
1423
Advantage
68
Anvia Chemicals, LLC
Tel
--
Fax
--
Email
sales@anviachem.com
Country
United States
ProdList
3933
Advantage
0
Ring Specialty Chemicals Inc.
Tel
--
Fax
--
Email
info@ringchemicals.com
Country
United States
ProdList
888
Advantage
39
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
ChemService Inc.
Tel
--
Fax
--
Country
United States
ProdList
6379
Advantage
68
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
Pressure Chemical Co.
Tel
--
Fax
--
Email
service@presschem.com
Country
United States
ProdList
111
Advantage
76
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
Advanced Synthesis Technologies
Tel
--
Fax
--
Email
sales@advancedsynthesis.com
Country
United States
ProdList
4775
Advantage
61
Gelest, Inc.
Tel
--
Fax
--
Email
info@gelest.com
Country
United States
ProdList
3973
Advantage
84
Aagile Labs Division of Tyger Scientific
Tel
--
Fax
--
Email
tygersci@yahoo.com
Country
United States
ProdList
6568
Advantage
68
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
More
Less

View Lastest Price from Tetrakis(triphenylphosphine)palladium manufacturers

Shanghai Daken Advanced Materials Co.,Ltd
Product
Tetrakis(triphenylphosphine)palladium 14221-01-3
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG /month
Release date
2021-11-05
Shanghai UCHEM Inc.
Product
Tetrakis(triphenylphosphine)palladium(0) 14221-01-3
Price
US $111.00-422.00/g
Min. Order
5g
Purity
0.98
Supply Ability
25kg
Release date
2023-12-13
Hebei Weibang Biotechnology Co., Ltd
Product
Tetrakis(triphenylphosphine)palladium 14221-01-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-12-09

14221-01-3, Tetrakis(triphenylphosphine)palladiumRelated Search:

Cisplatin Bis(diphenylphosphinophenyl)ether palladium (II) dichloride Tetrakis(ethylmethylamino)vanadium(IV) TETRAKIS(DIETHYLAMINO)HAFNIUM TETRAKIS(DIETHYLAMINO)ZIRCONIUM TETRAKIS(ETHYLMETHYLAMINO)ZIRCONIUM TETRAKIS(DIMETHYLAMIDO)HAFNIUM(IV) Palladium chloride Bis(tricyclohexylphosphine)palladium(II) Dichloride Tetrakis(triphenylphosphine)platinum Palladium Bis(triphenylphosphine)palladium(II) chloride TETRAPHENYLOLETHANE GLYCIDYL ETHER Triphenylphosphine Tetraacetylethylenediamine Tetrakis(hydroxymethyl)phosphonium chloride Tetraisopropyl di(dioctylphosphate) titanate Tetrakis(hydroxymethyl)phosphonium sulfate

  • (beta-4)-palladiu
  • Tetrakis(triphenylphosphine)palladium(0), 99.8% (metals basis), Pd 9% min
  • Tetrakis(triphenylphosphine)palladium(0) Store refrigerated Protect from light
  • Tetrakis(triphenylphosphine) p
  • Tetrakis(triphenylphosphine)palladiu
  • Tetrakis(triphenylphosphine)Palladium(0), Pd(PPh3)4
  • Terakis(triphenylphosphine)palladi
  • Tetrakis(triphenylphosphine)palladiuM(0), 99.8%
  • Tetrakis(triphenylphosphine)palladiuM(0), 9% Pd, Product of UMicore
  • etrakis(triphenylphosphine)palladiuM
  • Tetrakis (triphenyl phosphene)palladiuM(o)
  • Tetrakis(triphenylphosphine)palladiuM(0) >=99.99% trace Metals basis
  • Tetrakis[triphenylphosphine]palladium(0), ChemDose? tablets
  • Tetrakis(triphenylphosphine)palladium(0) Vetec(TM) reagent grade, 98%
  • Tetrakis(triphenylphosphine)palladium, polymer-bound 200-400 mesh, extent of labeling: 0.5-0.9 mmol/g loading, 2 % cross-linked with divinylbenzene
  • Tetrakis[triphenylphosphine]palladium(0), ChemDose(TM) tablets Loading: 2mumol per tablet
  • Tetrakis(triphenylphosphine)palladiuM(0), 99.8% (Metals basis), Pd 9%
  • Tetrakis(tripheny1phosphine)palladium
  • Tetrakis(triphenylphosphine)palladium(II),98% Pd(PPh3)4
  • etrakis(triphenylphosphine)palladium(0)
  • Tetrakis(triphenylphosphine)palladium(0), 99.5% trace metals basis
  • Tetrakis(tripheny1phosphine)palladium (Pd(PPh3)4)
  • TETRAKIS(TRIPHENYLPHOSPHINE)PALLADIUM(0): 99.9%
  • adium(0)
  • phosphine)paL
  • Tetrakis(triphenyL
  • Pd(PPh3)4(tetrakis(triphenyl-phosphine)palladium(0))
  • Tetrakis-(triphenylphosphane)-palladium
  • Pd9.2%Tetrakis(triphenylphosphine palladium
  • Tetrakis(triphenylphosphine)palladium, tech
  • TETRAKIS(TRIPHENYLPHOSPHNE) PALLADIUM (0)
  • Tetra(triphenylphosphine) palladium
  • Palladium-tetrakis(triphenylphosphine) impregnated tablets, ChemDose(R), Tetrakis(triphenylphosphine)palladium(0) impregnated tablets
  • Tetrakis[triphenylphosphine]palladium(0), ChemDose(R) tablets
  • Tetrakis (iphenylphosphine) Pplladium
  • Tetrakis(triphenylphosphine)palladium,99% (99.9+%-Pd)
  • Tetrakis(Triphenylphosphine)Palladium(0) (Metals Basis), Pd 9% Min
  • Tetrakis(triphenylphosphine)palladium(0),99%
  • Palladiumhydroxideoncarbon5%Soldonadrybasis
  • Tetrakis(triphenylphosphine)palladium(0) [9.2% Pd]
  • Tetrakis(triphenylphosphine)palladium(0) ,0% [9.2%Pd,Light yellow green powder]
  • Tetrakis(triphenylphosphine)palladium(0),Palladium-tetrakis(triphenylphosphine)
  • Terakis(triphenylphosphine)palladium
  • Tetrakis(triphenylphosphine)palladium (O), 99% (99.9+%-Pd)
  • Tetrakis(triphenylphosphine)palladiuM(II)
  • Tetrakis(triphenylphosphine)palladiuM(0) ,0% [9.2%Pd]
  • Tetrakis(triphenylphosphine)palladiuM (0),98% Pd(PPh3)4
  • Tetrakis(triphenylphosphine)palladiuM(0), 99.9%, (trace Metal basis)
  • Tetrakis(triphenylphosphine)palladium(0)≥ 99.5% (≥ 9% Pd, Assay)
  • PS-DVB
  • TETRAKIS(TRIPHENYLPHOSPHIN)-PALLADIUM(O)
  • TETRAKIS-(TRIPHENYLPHOSPHANYL)-PALLADIUM
  • TETRAKIS(TRIPHENYLPHOSPHINE)PALLADIUM
  • TETRAKIS(TRIPHENYLPHOSPHINE)PALLADIUM(0)
  • TETRAKIS(TRIPHENYLPHOSPHINE)PALLADIUM(O)
  • TETRAKIS(TRIPHENYLPHOSPHINE)PALLADIUM POLYMER BOUND
  • PALLADIUM-TETRAKIS(TRIPHENYLPHOSPHINE)
  • PALLADIUM-TETRAKIS(TRIPHENYLPHOSPHINE) POLYMER-BOUND