ChemicalBook > CAS DataBase List > 2-Ethyl-3-methylpyrazine

2-Ethyl-3-methylpyrazine

Product Name
2-Ethyl-3-methylpyrazine
CAS No.
15707-23-0
Chemical Name
2-Ethyl-3-methylpyrazine
Synonyms
Pyrazine, 2-ethyl-3-methyl-;3-METHYL-2-ETHYLPYRAZINE;FEMA 3155;FEMA NUMBER 3155;filbert pyrazine;Ethyl-3-Methylpyraz;2-Ethyl-3-Methylpyra;3-ETHYL-2-METHYLPYRAZINE;2-METHYL-3-ETHYLPYRAZINE;2-ETHYL-3-METHYLPYRAZINE
CBNumber
CB6170305
Molecular Formula
C7H10N2
Formula Weight
122.17
MOL File
15707-23-0.mol
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2-Ethyl-3-methylpyrazine Property

Boiling point:
57 °C10 mm Hg(lit.)
Density 
0.987 g/mL at 25 °C
vapor pressure 
1.74hPa at 20℃
FEMA 
3155 | 2-ETHYL-3-METHYLPYRAZINE
refractive index 
n20/D 1.503(lit.)
Flash point:
138 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
sparingly soluble
pka
1.94±0.10(Predicted)
Specific Gravity
0.987
color 
Colorless to Light yellow
Odor
at 0.10 % in dipropylene glycol. nutty peanut musty corn raw earthy bread
Odor Type
nutty
biological source
synthetic
Water Solubility 
sparingly soluble
JECFA Number
768
BRN 
956775
LogP
1.42 at 25℃
CAS DataBase Reference
15707-23-0(CAS DataBase Reference)
NIST Chemistry Reference
Pyrazine, 2-ethyl-3-methyl-(15707-23-0)
EPA Substance Registry System
Pyrazine, 2-ethyl-3-methyl- (15707-23-0)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-24/25
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
RTECS 
UQ3335000
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
3
PackingGroup 
III
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W315508
Product name
2-Ethyl-3-methylpyrazine
Purity
≥98%, FCC, FG
Packaging
1 unit
Price
$49.38
Updated
2025/07/31
Sigma-Aldrich
Product number
W315508
Product name
2-Ethyl-3-methylpyrazine
Purity
≥98%, FCC, FG
Packaging
1 unit
Price
$49.38
Updated
2025/07/31
Sigma-Aldrich
Product number
W315508
Product name
2-Ethyl-3-methylpyrazine
Purity
≥98%, FCC, FG
Packaging
100g
Price
$186.55
Updated
2025/07/31
Sigma-Aldrich
Product number
W315508
Product name
2-Ethyl-3-methylpyrazine
Purity
≥98%, FCC, FG
Packaging
1kg
Price
$619
Updated
2025/07/31
Sigma-Aldrich
Product number
W315508
Product name
2-Ethyl-3-methylpyrazine
Purity
≥98%, FCC, FG
Packaging
5kg
Price
$2400
Updated
2025/07/31
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2-Ethyl-3-methylpyrazine Chemical Properties,Usage,Production

Chemical Properties

clear colorless to slightly yellow liquid

Chemical Properties

2-Ethyl-3-methylpyrazine has a strong, raw-potato, roasted, earthy odor.

Occurrence

Reported found in bakery products, roasted barley, coffee, peanuts, filberts, potato products, soy products, roasted and fried chicken, beef, pork, beer, rum, cocoa, coffee, tea, malt, shrimp and crayfish.

Uses

2-Ethyl-3-methylpyrazine is used in preparation of Chinese chestnut pyrolyzate and their application to e-cigarette.

Uses

Food additive.

Definition

ChEBI: 2-Ethyl-3-methylpyrazine, 9CI is a member of pyrazines.

Preparation

By condensation of ethylenediamine with 2,3-pentanedione.

Aroma threshold values

Detection: 2 ppm (130 ppb in water)

Taste threshold values

Taste characteristics at 10 ppm: nutty, peanut, musty corn-like with raw and oily nuances.

Hazard

Moderately toxic by ingestion.

Flammability and Explosibility

Not classified

Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating fumes.

Synthesis

600-14-6

107-15-3

15707-23-0

2,3-Pentanedione, ethylenediamine and anhydrous ethanol were mixed in a three-necked flask at -5 to 3°C in a mass ratio of 1:1.1:70 and the reaction was stirred for 7 hours. After completion of the reaction, the system was slowly warmed to room temperature and stirring was continued for 3 hours. Subsequently, the temperature was raised to 65-70°C and refluxed for 4 hours. After the reaction mixture was cooled to 30-40 °C, xylene and potassium hydroxide catalyst was added to a three-necked flask, where the mass ratio of 2,3-pentanedione, potassium hydroxide to xylene was 1:0.8:2.8. Heating was continued to 65-70 °C and refluxed for 5 h. The reaction mixture was then cooled to room temperature and stirred for 7 h. The reaction mixture was then cooled to room temperature and stirred for 4 h. After the reaction was completed, it was cooled to room temperature and subjected to filtration. The filtrate was distilled at atmospheric pressure and the resulting concentrate was extracted with saturated brine solution, the organic phases were combined and dried with anhydrous sodium sulfate. The dried organic phase was filtered and subjected to atmospheric pressure distillation to collect the 55-60 °C/1.33 kPa fraction to give 2-ethyl-3-methylpyrazine in more than 93.5% product yield.

References

[1] Patent: CN107556250, 2018, A. Location in patent: Paragraph 0024; 0029; 0035; 0041; 0049; 0053

2-Ethyl-3-methylpyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Ethyl-3-methylpyrazine Suppliers

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View Lastest Price from 2-Ethyl-3-methylpyrazine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-Ethyl-3-methylpyrazine 15707-23-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-06-26
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Ethyl-3-methylpyrazine 15707-23-0
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-05
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Ethyl-3-methylpyrazine 15707-23-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-28

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