2-ISOPROPOXYETHANOL Property

Melting point:

-60 °C

Boiling point:

42-44 °C13 mm Hg(lit.)

Density 

0.903 g/mL at 25 °C(lit.)

vapor pressure 

5.99 hPa (25 °C)

refractive index 

n20/D 1.41(lit.)

Flash point:

114 °F

storage temp. 

Store below +30°C.

solubility 

>100g/l soluble

pka

14.47±0.10(Predicted)

form 

Liquid

color 

Colorless to Almost colorless

explosive limit

1.6-13.0%(V)

Water Solubility 

It is soluble in water.

BRN 

1732184

Exposure limits

TLV-TWA skin 25 ppm (106 mg/m³) (ACGIH). .

Stability:

Stable. Incompatible with strong oxidizing agents. Combustible.

InChIKey

HCGFUIQPSOCUHI-UHFFFAOYSA-N

LogP

0.43 at 20℃

CAS DataBase Reference

109-59-1(CAS DataBase Reference)

EPA Substance Registry System

Isopropoxyethanol (109-59-1)

Safety

Hazard Codes 

Xn

Risk Statements 

20/21-36

Safety Statements 

24/25

RIDADR 

UN 2929 6.1/PG 2

WGK Germany 

1

RTECS 

KL5075000

Autoignition Temperature

240 °C

TSCA 

Yes

HS Code 

2909 44 00

HazardClass 

3

PackingGroup 

III

Hazardous Substances Data

109-59-1(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 5111 mg/kg LD50 dermal Rabbit 1445 mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2-ISOPROPOXYETHANOL Chemical Properties,Usage,Production

Chemical Properties

colourless liquid

Uses

2-Isopropoxyethanol was used to study the products of the gas-phase reactions of OH radical with n-butyl methyl ether and 2-isopropoxyethanol in the presence of NO. 2-Isopropoxyethanol was used to develop methodology for evaluating electromagnetic sensor performance in nonrelaxing and nonconducting (e.g., sandy soil) media

Uses

Ethylene glycol monoisopropyl ether (EGIE) is used as a solvent for resins, dyes, and cellulose esters, and in coatings..

Uses

Solvent in latex paints, lacquers, and other coatings, resins, coalescing aids, and coupling solvents

General Description

A clear liquid. Density 0.903 g / cm3. Flash point 114°F. An irritant.

Air & Water Reactions

Flammable. Oxidizes in air to form unstable peroxides that may explode spontaneously [Bretherick, 1979 p.151-154, 164]. Water soluble .

Reactivity Profile

2-ISOPROPOXYETHANOL acts both as an alcohol and ether. May react violently with strong oxidizing agents. May generate flammable and/or toxic gases with alkali metals, nitrides, and other strong reducing agents. May initiate the polymerization of isocyanates and epoxides.

Hazard

Combustible liquid with flash p 49C. Toxic by skin absorption.

Health Hazard

EGIE shows low toxicity from inhalation, ingestion, and skin absorption. The toxic symptomsaresimilartothoseproducedbythe butyl ether of the ethylene glycol. The effects noted in rats from exposure to 1000 ppm for 6 hours were hemoglobinuria, anemia, and lung congestion (Gage 1970). Other effectsobservedwereincreasesintheosmotic fragility of the red blood cells. Such effects were manifested at EGIE concentrations of >200 ppm. A 4-hour exposure to 4000 ppm was lethal to rats. In human exposure to this compound can result in anemia
LD50 value, oral (rats): 5660 mg/kg
No testicular toxicity was observed in rats from a single exposure to 3500 ppm of EGIE in air (Doe 1984)..

Health Hazard

May be harmful by inhalation, ingestion or skin absorption. May cause skin and eye irritation.

Fire Hazard

Special Hazards of Combustion Products: Emits toxic fumes when heated upon decomposition.

Waste Disposal

Chemical incineration is the most suitable method of destruction. Drain disposal may be done for small amounts of EGIE.