3-(4-Morpholinyl)aniline

Product Name: 3-(4-Morpholinyl)aniline
CAS No.: 159724-40-0
Chemical Name: 3-(4-Morpholinyl)aniline
Synonyms: AKOS BB-8950;3-Morpholinoaniline;3-morpholinobenzenamine;3-MORPHOLIN-4-YLANILINE;3-(4-Morpholinyl)aniline;3-Morpholin-4ylaniline 97%;4-(3-Aminophenyl)morpholine;3-Morpholin-4-yl-phenylamine;3-(Morpholin-4-yl)aniline 97+%;Benzenamine, 3-(4-morpholinyl)-
CBNumber: CB6175557
Molecular Formula: C10H14N2O
Formula Weight: 178.23
MOL File: 159724-40-0.mol

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3-(4-Morpholinyl)aniline Property

Melting point:: 118 °C
Boiling point:: 0°C
Density: 1.149±0.06 g/cm3(Predicted)
Flash point:: 0°C
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated)
form: Solid
pka: 5.27±0.10(Predicted)
color: Pale Brown to Brown

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38-22
Safety Statements: 22-36/37/39-26
RIDADR: UN2811
Hazard Note: Harmful
HazardClass: IRRITANT
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M725290
Product name: 3-Morpholin-4-ylaniline
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: OR1383
Product name: 3-(Morpholin-4-yl)aniline
Purity: 97+%
Packaging: 250mg
Price: $15
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H30-1-X3
Product name: 3-(Morpholin-4-yl)aniline
Purity: 97.0%
Packaging: 250mg
Price: $16
Updated: 2021/12/16

Matrix Scientific

Product number: 059187
Product name: 3-Morpholin-4-yl-aniline
Purity: 95+%
Packaging: 1g
Price: $21
Updated: 2021/12/16

Apolloscientific

Product number: OR1383
Product name: 3-(Morpholin-4-yl)aniline
Purity: 97+%
Packaging: 1g
Price: $22
Updated: 2021/12/16

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3-(4-Morpholinyl)aniline Chemical Properties,Usage,Production

Uses

3-Morpholin-4-ylaniline can be used to prevent and treat influenza.

Definition

ChEBI: 3-Morpholin-4-ylaniline is a member of morpholines.

Synthesis

116922-22-6

159724-40-0

To a solution of 4-(3-nitrophenyl)morpholine (43) (4.16 g, 20 mmol) in methanol (50 mL) cooled to 0 °C in an ice water bath was added 10% palladium/carbon catalyst (460 mg). The reaction mixture was stirred at room temperature and under hydrogen atmosphere (1 atm) for 16 hours. Upon completion of the reaction, the catalyst was removed by filtration through diatomaceous earth (Celite?). The filtrate was dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 3-(4-morpholinyl)aniline (3.39 g, 95.2%) as an orange solid. The product was analyzed by LC-MS showing m/z(ESP): 179 [M+H]? and retention time (R/T) of 1.69 min, which is sufficiently pure to be used in subsequent reactions without further purification.

References

[1] Journal of Medicinal Chemistry, 2005, vol. 48, # 26, p. 8261 - 8269
[2] Patent: US2006/199804, 2006, A1. Location in patent: Page/Page column 31
[3] Journal of Medicinal Chemistry, 2008, vol. 51, # 3, p. 407 - 416
[4] Patent: WO2007/339, 2007, A1. Location in patent: Page/Page column 52
[5] Patent: WO2003/90912, 2003, A1. Location in patent: Page/Page column 76

3-(4-Morpholinyl)aniline Preparation Products And Raw materials

Raw materials

Ethanol N,N-Dimethylformamide Ammonium formate Potassium carbonate Palladium Ethyl acetate Hydrogen Methanol Dimethyl sulfoxide 1-Fluoro-3-nitrobenzene Morpholine

Preparation Products

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3-(4-Morpholinyl)aniline Suppliers

Belgium 1 China 97 Germany 3 India 3 Ukraine 1 United Kingdom 7 United States 16 Global 128

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
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Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
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Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
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China DongFan Chemical Co.,LTD

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Shanghai Ennopharm Co., Ltd.

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Syntechem Co.,Ltd

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Hangzhou Yuhao Chemical Technology Co., Ltd

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Chengdu Forest Science and Technology Development Co., Ltd.

Tel: 18030648795
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ProdList: 2000
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Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

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View Lastest Price from 3-(4-Morpholinyl)aniline manufacturers

Career Henan Chemical Co

Product: 3-(4-Morpholinyl)aniline 159724-40-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97-99%
Supply Ability: 1000KGS
Release date: 2019-12-18

159724-40-0, 3-(4-Morpholinyl)anilineRelated Search:

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159724-40-0

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