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N,N-Dimethylacetoacetamide

Description Application
Product Name
N,N-Dimethylacetoacetamide
CAS No.
2044-64-6
Chemical Name
N,N-Dimethylacetoacetamide
Synonyms
DMAA;DIMETHYLACETOACETAMIDE;Acetoacetamide, N,N-dimethyl-;DMAA80;Fanda DMAA;Fanda DMAA 80%;DMAA 80% in H2O;AKOS BBS-00006508;TIMTEC-BB SBB007704;N,N-Dimethylacetoace
CBNumber
CB6181037
Molecular Formula
C6H11NO2
Formula Weight
129.16
MOL File
2044-64-6.mol
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N,N-Dimethylacetoacetamide Property

Melting point:
-55 °C
Boiling point:
105 °C(lit.)
Density 
1.067 g/mL at 25 °C
vapor pressure 
19.84hPa at 25℃
refractive index 
n20/D 1.447
Flash point:
252 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
H2O: soluble
pka
12.82±0.46(Predicted)
form 
clear liquid
color 
APHA: ≤350
Water Solubility 
hydrolysis SLOWLY
BRN 
1755038
LogP
0.91 at 25℃
CAS DataBase Reference
2044-64-6(CAS DataBase Reference)
NIST Chemistry Reference
N,N-Dimethylacetoacetamide(2044-64-6)
EPA Substance Registry System
Butanamide, N,N-dimethyl-3-oxo- (2044-64-6)
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Safety

Hazard Codes 
N
Risk Statements 
36/37/38-51/53
Safety Statements 
26-36-61
RIDADR 
UN 3082 9 / PGIII
WGK Germany 
-
RTECS 
AK4035000
HS Code 
2924.19.1150
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H320Causes eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
537373
Product name
N,N-Dimethylacetoacetamide solution
Purity
80% in H2O
Packaging
500ml
Price
$160
Updated
2024/03/01
Sigma-Aldrich
Product number
537373
Product name
N,N-Dimethylacetoacetamide solution
Purity
80% in H2O
Packaging
2l
Price
$186
Updated
2024/03/01
TCI Chemical
Product number
D0642
Product name
N,N-Dimethylacetoacetamide
Purity
>97.0%(GC)
Packaging
25mL
Price
$19
Updated
2024/03/01
TCI Chemical
Product number
D0642
Product name
N,N-Dimethylacetoacetamide
Purity
>97.0%(GC)
Packaging
500mL
Price
$83
Updated
2024/03/01
Sigma-Aldrich
Product number
690848
Product name
N,N-Dimethylacetoacetamide solution
Purity
Lonza quality, 79.0-83.0% (calculated)
Packaging
25kg
Price
$566
Updated
2022/05/15
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N,N-Dimethylacetoacetamide Chemical Properties,Usage,Production

Description

N,N-dimethylacetoacetamide is a clear, colorless to yellow liquid used as a general purpose, low color generating co-promoter for many unsaturated polyester (FRP) resin formulations. It is also used in the production of low VOC unsaturated polyester (FRP) systems for coatings and as an intermediate for the production of insecticides.

Application

N,N-Dimethylacetylacetamide is an organic intermediate that can be used to prepare thioamide compounds. As an important thiocarboxylic acid derivative, thioamide compounds have received extensive attention in pharmaceutical synthesis, chemical engineering and related fields. Thioamide and its derivatives have a wide range of applications in analysis, materials, and electrochemistry. They are not only used in the production of polymerization inhibitors, catalysts, stabilizers, pesticides, etc., but also in the production of pharmaceutical raw materials, vulcanizing agents, and chemicals. Coupling reagents, collectors, etc.

Chemical Properties

Clear, colorless to yellow liquid

Uses

N,N-Dimethylacetamide is used as intermediate for the production of insecticides, e.g. dicrotophos and as a promoter in unsaturated polyester resins. Product Data Sheet

Uses

N,N-Dimethyl-3-oxobutanamide is used as a reactant in the asymmetric hydrogenation of functionalized ketones in presence of chiral bis(diphenylphosphino)binaphthyl ruthenium complex.

General Description

The product is an 80% solution of N,N-dimethylacetoacetamide (DMAA) in water.

Flammability and Explosibility

Non flammable

Toxicology

N,N-Dimethylacetoacetamide (DMAAm) is a β-dicarbonyl compound that is utilized as a co-promoter in the production of unsaturated polyester resins used in coating materials and as an industrial intermediate in insecticide synthesis. Patents have also been issued for its use in hair colorants. However, DMAAm had limited toxicology and information available. DMAAm appears to have low toxicity in rodents. Smyth et al. reported an oral LD50 in male CarworthWistar rats of 22.6mL/kg (estimated to be approximately 19.8g/kg) and a dermal LD50 in male New Zealand rabbits of 14.1mL/kg (12.4g/kg) (single 8-h exposure). Oral gavage administration of DMAAm did not result in any mortality in rats (strain and gender not reported) at doses up to 3.2g/kg. DMAAm has been identified as a hydrolytic product and a degradation product of the insecticide dicrotophos ((dimethoxyphosphinyloxy)-N, N-dimethylcis-crotonamide) in soil, but was not found as a urinary metabolite of this insecticide in rats[1].

References

[1] Timothy Fennell. “Disposition and metabolism of N,N-dimethylacetoacetamide in male F344 and Wistar-Han rats and female B6C3F1 mice.” Xenobiotica 41 11 (2011): 1013–20.

N,N-Dimethylacetoacetamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N-Dimethylacetoacetamide Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
RYSS TECH LTD
Tel
400-188-0725 +86 21 34310725 13611771617
Fax
+86 21 34311076
Country
China
ProdList
2002
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
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View Lastest Price from N,N-Dimethylacetoacetamide manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
N,N-Dimethylacetoacetamide 2044-64-6
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-09
Hebei Longbang Technology Co., Ltd
Product
N,N-Dimethylacetoacetamide 2044-64-6
Price
US $6.00/kg
Min. Order
1kg
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-05-13
Hebei Weibang Biotechnology Co., Ltd
Product
N,N-Dimethylacetoacetamide 2044-64-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-25

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