1,3-Dibromopropane Property

Melting point:

-34 °C (lit.)

Boiling point:

167 °C (lit.)

Density 

1.989 g/mL at 25 °C (lit.)

vapor density 

7 (vs air)

vapor pressure 

2.6 hPa (20 °C)

refractive index 

n20/D 1.524(lit.)

Flash point:

54 °C

storage temp. 

Store below +30°C.

solubility 

1.68g/l

form 

Liquid

color 

Clear colorless to yellow

Water Solubility 

1.7 g/L (30 ºC)

Merck 

14,9713

BRN 

635662

Dielectric constant

4.3（20℃）

Stability:

Stable. Incompatible with strong oxidizing agents, strong bases. Flammable.

InChIKey

VEFLKXRACNJHOV-UHFFFAOYSA-N

CAS DataBase Reference

109-64-8(CAS DataBase Reference)

NIST Chemistry Reference

Propane, 1,3-dibromo-(109-64-8)

EPA Substance Registry System

Propane, 1,3-dibromo- (109-64-8)

Safety

Hazard Codes 

Xn,N,Xi

Risk Statements 

10-22-38-51/53-36/37/38

Safety Statements 

16-26-36-61-24/25

RIDADR 

UN 1993 3/PG 3

WGK Germany 

2

RTECS 

TX8575000

TSCA 

Yes

HazardClass 

3

PackingGroup 

III

HS Code 

29033036

Hazardous Substances Data

109-64-8(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 315 mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H315Causes skin irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

1,3-Dibromopropane Chemical Properties,Usage,Production

Chemical Properties

1,3-Dibromopropane is a colourless to slightly yellow liquid with sweet odor. soluble in ether, acetone and chloroform, insoluble in water. Decomposes when exposed to heat for a long time and is partially converted to 1,2-dibromopropane. Boiling with water produces propylene glycol. It is used substrate specificity of haloalkane dehalogenases.

Uses

1,3-Dibromopropane is used to prepare C3-bridged compounds through C-N coupling reactions. It is used in the preparation of 2,3,4,5-tetrahydro-7,7-diphenylimidazo- [2,1-b]-thiazine-6(7H)-one by reacting with potassium salt of 5,5-diphenyl-2-thiohydantoin.

General Description

1,3-Dibromopropane is a dihalogenated propane. It undergoes reduction catalyzed by electrogenerated solution-phase nickel(I) salen and nickel(I) salen confined in a polymer film on the surface of a carbon electrode to afford cyclopropane and propylene, respectively.

Hazard

Colorless liquid; sweet odor. Insoluble in water; soluble in organic solvents. Combustible.

Synthesis

1,3-Dibromopropane can be prepared via the free radical addition between allyl bromide and hydrogen bromide. It can derived from the reaction of propylene glycol with brominated hydrochloric acid.

Purification Methods

1,3-Dibromopropane [109-64-8] M 201.9, f -34.4o, b 63 -63.5o/26mm, 76 -77o/40mm, 9 0o/80mm, 165o/atm, d 4 1.977, n 1.522. Wash the dibromide with dilute aqueous Na2CO3, then water. Dry and fractionally distil it under reduced pressure. [Beilstein 1 IV 216.]