Quinestrol

Product Name: Quinestrol
CAS No.: 152-43-2
Chemical Name: Quinestrol
Synonyms: eston;eecpe;w3566;EE2CPE;qui-lea;estrovis;plestrovis;QUINESTROL;estrovister;estrovis4000
CBNumber: CB6189992
Molecular Formula: C25H32O2
Formula Weight: 364.52
MOL File: 152-43-2.mol

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Quinestrol Property

Melting point:: 107-108°
alpha: D25 +5° (c = 0.5 in dioxane)
Boiling point:: 435.69°C (rough estimate)
Density: 1.0693 (rough estimate)
refractive index: 1.4480 (estimate)
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly)
pka: 13.10±0.40(Predicted)
form: Solid
color: White to Off-White
Merck: 14,8055
CAS DataBase Reference: 152-43-2(CAS DataBase Reference)

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Safety

Hazard Codes: T
Risk Statements: 45-61-20/21/22-46
Safety Statements: 53-22-36/37/39-45
WGK Germany: 3
RTECS: RC8948000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H350May cause cancer

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E7887
Product name: 17α-Ethynylestradiol 3-cyclopentyl ether
Packaging: 100mg
Price: $60.5
Updated: 2024/03/01

Sigma-Aldrich

Product number: PH001408
Product name: 3-(CYCLOPENTYLOXY)-17-ETHYNYLESTRA-1(10),2,4-TRIEN-17-OL
Purity: AldrichCPR
Packaging: 1MG
Price: $81.6
Updated: 2023/06/20

Cayman Chemical

Product number: 10006320
Product name: Quinestrol
Purity: ≥98%
Packaging: 100mg
Price: $36
Updated: 2024/03/01

Cayman Chemical

Product number: 10006320
Product name: Quinestrol
Purity: ≥98%
Packaging: 250mg
Price: $84
Updated: 2024/03/01

Cayman Chemical

Product number: 10006320
Product name: Quinestrol
Purity: ≥98%
Packaging: 500mg
Price: $155
Updated: 2024/03/01

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Quinestrol Chemical Properties,Usage,Production

Description

Quinestrol is a synthetic estrogen that is effective in hormone replacement therapy. It is a 3-cyclopentyl ether of ethynyl estradiol. After gastrointestinal absorption, it is stored in adipose tissue, where it is slowly released and metabolized in the liver to its active form, ethinyl estradiol. Quinestrol has found limited use in suppressing lactation in postpartum women and, in combination with synthetic progestogens, as contraceptive therapy, although additional studies are needed for both applications.

Uses

antibacterial, antimycoplasmal, isoleucyl-tRNA synthetase inhibitor

Uses

Quinestrol is an estrogen-like compound.

Definition

ChEBI: Quinestrol is a 17-hydroxy steroid and a terminal acetylenic compound. It has a role as a xenoestrogen. It is functionally related to a 17beta-estradiol.

brand name

Estrovis (Parke-Davis).

References

[1]. baumgardner sb, condrea h, daane ta, et al. replacement estrogen therapy for menopausal vasomotor flushes. comparison of quinestrol and conjugated estrogens. obstet gynecol. 1978 apr;51(4):445-52.
[2]. skouby, s.o. criteria for the selection of an optimal estrogen replacement. gynecological endocrinology 15, 60-67 (2001).
[3]. li j, chen f, li c,et al. quinestrol induces spermatogenic apoptosis in vivo via increasing pro-apoptotic proteins in adult male mice. tissue cell. 2014 oct;46(5):318-25.
[4]. li j, chen f, chen y, et al. mitochondrial- and fas-l-mediated pathways involved in quinestrol induced spermatogenic apoptosis in adult rat testes. toxicol mech methods. 2014 dec;24(9):609-15.

Quinestrol Preparation Products And Raw materials

Raw materials

Tetrahydrofuran Bromocyclopentane

Preparation Products

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Quinestrol Suppliers

China 101 Europe 2 Germany 1 India 2 Japan 1 South Korea 1 Switzerland 2 United Kingdom 4 United States 20 Global 134

LGM Pharma

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TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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Aladdin Scientific

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View Lastest Price from Quinestrol manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Quinestrol 152-43-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000KG
Release date: 2024-07-16

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Quinestrol 152-43-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2024-04-25

Nantong Guangyuan Chemicl Co,Ltd

Product: Quinestrol 152-43-2
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2023-11-01

152-43-2, QuinestrolRelated Search:

PENTYL ETHER Difenoconazole Ethylbenzene Dimethyl ether 2-Butoxyethanol Ethynyl estradiol 5-METHYL-1-HEXYN-3-OL ISONONYLPHENOL-ETHOXYLATE (S)-1-OCTYN-3-OL 3-CYCLOHEXYL-1-PROPYNE 1-Ethoxy-4-(trans-4-propylcyclohexyl)benzene 3,6-DIMETHYL-1-HEPTYN-3-OL CYCLOPENTYLACETYLENE 17-alpha-methyloestradiol-17-beta Nilestriol 4-METHYL-1-PENTYN-3-OL 3-Methylether-estradiol Diethyl ether

17-alpha-ethinylestradiol3-cyclopentylether

3-(cyclopentyloxy)-(17-alpha)-19-norpregna-5(10)-trien-20-yn-17-ol

3-(cyclopentyloxy)-19-nor-17-alpha-pregna-1,3,5(10)-trien-20-yn-17-ol

5(10)-trien-20-yn-17-ol,3-(cyclopentyloxy)-19-nor-17-alpha-pregna-3

eecpe

eston

17ALPHA-ETHYLNYL-1,3,5[10]ESTRATRIENE-3,17BETA-DIOL 3-CYCLOPENTYL ETHER

17a-ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-cyclopentyl ether

17a-ethynylestradiol 3-cyclopentyl ether

(17ALPHA-3-(CYCLOPENTYLOXY)-19-NORPREGNA-1,3,5(10)TRIENE-20-YN-17-OL

17α-Ethynylestradiol 3-cyclopentyl ether

Quinestrol, 17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol 3-cyclopentyl ether

17a-Ethynylestradiol 3-cyclopentyl ether17a-ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-cyclopentyl ether

19-Nor-17a-pregna-1,3,5(10)-trien-20-yn-17-ol, 3-(cyclopentyloxy)-

3-(Cyclopentyloxy)-19-nor-17a-pregna-1,3,5(10)-trien-20-yn-17-ol<br />

3-Cyclopentyloxy-17a-ethynyl-1,3,5(10)-estratrien-17-ol

Ethynylestradiol-3-cyclopentyl ether

(17R)-3-(Cyclopentyloxy)-19-norpregna-1,3,5(10)-trien-20-yn-17-ol

(8R,9S,13S,14S,17R)-3-(cyclopentoxy)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol

(8R,9S,13S,14S,17R)-3-cyclopentyloxy-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol

17ALPHA-ETHYNYL-1,3,5(10)-ESTRATRIENE-3,17BETA-DIOL 3-CYCLOPENTYL ETHER

3-cyclopentyloxy-17-alpha-ethynyloestra-1,3,5(10)-trien-17-beta-ol

17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol 3-cyclopentyl ether

EE2CPE

Ethinylestradiol 3-cyclopentyl ether

8-cyclopentyloxy-1-ethynyl-12a-methyl-2,3,4,4a,4b,5,6,10b,11,12-decahydrochrysen-1-ol

estradiol-17-beta3-cyclopentylether

estrovis

estrovis4000

estrovister

plestrovis

qui-lea

w3566

QUINESTROL

17ALPHA-ETHYNYLESTRADIOL-3-CYCLOPENTYL ETHER

Quinestrol &gt

Quinestrol Quinestrol

19-Norpregna-1,3,5(10)-trien-20-yn-17-ol, 3-(cyclopentyloxy)-, (17α)-

QUINESTROL 152-43-2

Quinestrol (W-3566)

(8R,9S,13S,14S,17R)-3-(Cyclopentyloxy)-17-ethynyl-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ol

152-43-2

C25H32O2

BACTROBAN